Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine I (Q57396192)

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English	Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine I	article

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scholarly article

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28 February 2020

Dual angiotensin receptor and neprilysin inhibition as an alternative to angiotensin-converting enzyme inhibition in patients with chronic systolic heart failure: rationale for and design of the Prospective comparison of ARNI with ACEI to Determine Impact on Global Mortality and morbidity in Heart Failure trial (PARADIGM-HF) (English)

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28 February 2020

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systolic heart failure

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1

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28 February 2020

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28 February 2020

Marcelo Sanmartin

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28 February 2020

ESICM H1N1 Registry Contributors

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Jean Rouleau

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28 February 2020

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Milton Packer

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28 February 2020

Akshay S Desai

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28 February 2020

Jim Gong

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28 February 2020

Martin P Lefkowitz

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28 February 2020

Adel R Rizkala

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28 February 2020

Victor C Shi

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28 February 2020

Scott D Solomon

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28 February 2020

Karl Swedberg

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28 February 2020

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5 April 2013

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28 February 2020

European Journal of Heart Failure

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28 February 2020

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28 February 2020

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28 February 2020

1062-1073

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Europe PubMed Central

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28 February 2020

Neutral endopeptidase inhibition and the natriuretic peptide system: an evolving strategy in cardiovascular therapeutics

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2 November 2018

The angiotensin receptor neprilysin inhibitor LCZ696 in heart failure with preserved ejection fraction: a phase 2 double-blind randomised controlled trial.

1 reference

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Mendelian randomization study of B-type natriuretic peptide and type 2 diabetes: evidence of causal association from population studies

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2 November 2018

CONSENSUS to EMPHASIS: the overwhelming evidence which makes blockade of the renin-angiotensin-aldosterone system the cornerstone of therapy for systolic heart failure.

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2 November 2018

Concomitant angiotensin AT1 receptor antagonism and neprilysin inhibition produces omapatrilat-like antihypertensive effects without promoting tracheal plasma extravasation in the rat.

1 reference

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2 November 2018

Eplerenone in patients with systolic heart failure and mild symptoms

1 reference

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2 November 2018

Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study

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2 November 2018

Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study

1 reference

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2 November 2018

Pharmacokinetics and pharmacodynamics of LCZ696, a novel dual-acting angiotensin receptor-neprilysin inhibitor (ARNi).

1 reference

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2 November 2018

Predictors of fatal and non-fatal outcomes in the Controlled Rosuvastatin Multinational Trial in Heart Failure (CORONA): incremental value of apolipoprotein A-1, high-sensitivity C-reactive peptide and N-terminal pro B-type natriuretic peptide

1 reference

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2 November 2018

State of the art: using natriuretic peptide levels in clinical practice

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2 November 2018

Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin-mediated angioedema

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2 November 2018

Effect on survival and hospitalization of initiating treatment for chronic heart failure with bisoprolol followed by enalapril, as compared with the opposite sequence: results of the randomized Cardiac Insufficiency Bisoprolol Study (CIBIS) III.

1 reference

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2 November 2018

Tolerability of carvedilol and ACE-Inhibition in mild heart failure. Results of CARMEN (Carvedilol ACE-Inhibitor Remodelling Mild CHF EvaluatioN).

1 reference

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2 November 2018

Omapatrilat and enalapril in patients with hypertension: the Omapatrilat Cardiovascular Treatment vs. Enalapril (OCTAVE) trial

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2 November 2018

Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both

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2 November 2018

Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial

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2 November 2018

Hemodynamic and renal effects of low-dose brain natriuretic peptide infusion in humans: a randomized, placebo-controlled crossover study

1 reference

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2 November 2018

Pharmacokinetics of multiple doses of valsartan in patients with heart failure

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2 November 2018

Comparison of omapatrilat and enalapril in patients with chronic heart failure: the Omapatrilat Versus Enalapril Randomized Trial of Utility in Reducing Events (OVERTURE).

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2 November 2018

A randomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure

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2 November 2018

Systematic review of the impact of beta blockers on mortality and hospital admissions in heart failure

1 reference

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2 November 2018

Comparison of vasopeptidase inhibitor, omapatrilat, and lisinopril on exercise tolerance and morbidity in patients with heart failure: IMPRESS randomised trial

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2 November 2018

Importance of neuroendocrine activation in chronic heart failure. Impact on treatment strategies

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2 November 2018

Development and evaluation of the Kansas City Cardiomyopathy Questionnaire: a new health status measure for heart failure.

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2 November 2018

EuroQol--a new facility for the measurement of health-related quality of life

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2 November 2018

Beta-blockade in the management of chronic heart failure. Another step in the conceptual evolution of a neurohormonal model of the disease

1 reference

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2 November 2018

Enalapril in the treatment of mild-to-moderate heart failure in general medical practice: a prospective and multicentre study concerning 17,546 patients.

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2 November 2018

A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats

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2 November 2018

Significance of atrial natriuretic factor in chronic heart failure

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2 November 2018

Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS).

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2 November 2018

Effect of human atrial natriuretic peptide on blood glucose concentrations and hormone stimulation during insulin-induced hypoglycaemia in healthy man.

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2 November 2018

Role of endogenous atrial natriuretic factor in acute congestive heart failure

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2 November 2018

A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure

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2 November 2018

Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure

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2 November 2018

Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions

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2 November 2018

Neurohormonal inhibition and hemodynamic unloading during prolonged inhibition of ANF degradation in patients with severe chronic heart failure

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2 November 2018

The neurohormonal hypothesis: a theory to explain the mechanism of disease progression in heart failure

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2 November 2018

The clinical, cardiac, renal, arterial and neurohormonal effects of omapatrilat, a vasopeptidase inhibitor, in patients with chronic heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Outcome of patients with congestive heart failure treated with standard versus high doses of enalapril: a multicenter study. High Enalapril Dose Study Group

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

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inferred from PubMed ID database lookup

Enkephalinase inhibition increases plasma atrial natriuretic peptide levels, glomerular filtration rate, and urinary sodium excretion in rats with reduced renal mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

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Effects of UK 69 578: a novel atriopeptidase inhibitor

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12 December 2020

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inferred from PubMed ID database lookup

Clearance receptor-mediated control of atrial natriuretic factor in experimental congestive heart failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cardiorenal and neurohumoral effects of endogenous atrial natriuretic peptide in dogs with severe congestive heart failure using a specific antagonist for guanylate cyclase-coupled receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical outcome with enalapril in symptomatic chronic heart failure; a dose comparison

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Candoxatril improves exercise capacity in patients with chronic heart failure receiving angiotensin converting enzyme inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/23563576

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/EURJHF/HFT052

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28 February 2020

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Europe PubMed Central

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28 February 2020

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Europe PubMed Central

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28 February 2020

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