Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture (Q57371780)

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8 December 2019

title

Cholesterol-dependent generation of a seeding amyloid beta-protein in cell culture (English)

1 reference

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8 December 2019

author name string

T Mizuno

1

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8 December 2019

M Nakata

2

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8 December 2019

H Naiki

3

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8 December 2019

M Michikawa

4

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8 December 2019

R Wang

5

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8 December 2019

C Haass

6

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8 December 2019

K Yanagisawa

7

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8 December 2019

language of work or name

English

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publication date

1 May 1999

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Journal of Biological Chemistry

8 December 2019

published in

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8 December 2019

volume

274

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8 December 2019

issue

21

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8 December 2019

page(s)

15110-15114

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The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

8 December 2019

cites work

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Cholesterol-dependent generation of a unique amyloid beta-protein from apically missorted amyloid precursor protein in MDCK cells

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Structural neurology: are seeds at the root of neuronal degeneration?

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Models of amyloid seeding in Alzheimer's disease and scrapie: mechanistic truths and physiological consequences of the time-dependent solubility of amyloid proteins

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Polarized sorting of beta-amyloid precursor protein and its proteolytic products in MDCK cells is regulated by two independent signals

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Intracellular lipid heterogeneity caused by topology of synthesis and specificity in transport. Example: sphingolipids.

21 January 2018

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Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

21 January 2018

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COOH-terminal sequence of the cellular prion protein directs subcellular trafficking and controls conversion into the scrapie isoform

21 January 2018

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Cholesterol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform

21 January 2018

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Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform.

21 January 2018

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Polarized secretion of beta-amyloid precursor protein and amyloid beta-peptide in MDCK cells

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Concentration-dependent inhibitory effects of apolipoprotein E on Alzheimer's beta-amyloid fibril formation in vitro.

21 January 2018

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Acceleration of amyloid fibril formation by specific binding of Abeta-(1-40) peptide to ganglioside-containing membrane vesicles

21 January 2018

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The profile of soluble amyloid beta protein in cultured cell media. Detection and quantification of amyloid beta protein and variants by immunoprecipitation-mass spectrometry

21 January 2018

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Aggregation of secreted amyloid beta-protein into sodium dodecyl sulfate-stable oligomers in cell culture

21 January 2018

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Functional rafts in cell membranes

21 January 2018

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Axonal amyloid precursor protein expressed by neurons in vitro is present in a membrane fraction with caveolae-like properties.

21 January 2018

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Caveolae, plasma membrane microdomains for alpha-secretase-mediated processing of the amyloid precursor protein

21 January 2018

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Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

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A detergent-insoluble membrane compartment contains A beta in vivo.

21 January 2018

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GM1 ganglioside-bound amyloid beta-protein (A beta): a possible form of preamyloid in Alzheimer's disease.

21 January 2018

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Membrane disruption by Alzheimer beta-amyloid peptides mediated through specific binding to either phospholipids or gangliosides. Implications for neurotoxicity.

21 January 2018

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The interaction between Alzheimer amyloid beta(1-40) peptide and ganglioside GM1-containing membranes

21 January 2018

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21 January 2018

Conformational disease

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Prion diseases and the BSE crisis

21 January 2018

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Basolateral secretion of amyloid precursor protein in Madin-Darby canine kidney cells is disturbed by alterations of intracellular pH and by introducing a mutation associated with familial Alzheimer's disease

21 January 2018

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Ultrastructural localization of gangliosides; GM1 is concentrated in caveolae

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.21.15110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10329717%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference