Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial (Q57313084)

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scientific article published in April 2008

Language	Label	Description	Also known as
English	Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial	scientific article published in April 2008

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scholarly article

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3 January 2020

Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial (English)

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3 January 2020

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randomized experiment

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P Alan Barber

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Geoffrey A. Donnan

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Geoffrey A Donnan

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Graeme J. Hankey

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Graeme Hankey

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Graham Byrnes

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Christopher Levi

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Christopher Levi

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Stephen M Davis

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Mark W Parsons

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Kenneth S Butcher

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Andre Peeters

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Christopher Bladin

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Deidre A De Silva

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Jonathan B Chalk

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John N Fink

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Thomas E Kimber

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David Schultz

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Peter J Hand

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Judith Frayne

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Keith Muir

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Richard Gerraty

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Brian M Tress

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Patricia M Desmond

21

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Geoffrey A Donnan

2

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3 January 2020

Christopher Levi

4

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3 January 2020

P Alan Barber

7

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3 January 2020

Graham Byrnes

10

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3 January 2020

Graeme Hankey

17

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3 January 2020

EPITHET investigators

22

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3 January 2020

publication date

28 February 2008

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3 January 2020

Lancet Neurology

1 reference

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3 January 2020

7

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3 January 2020

299-309

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3 January 2020

4

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3 January 2020

randomized experiment

0 references

Tissue plasminogen activator for acute ischemic stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Thrombolysis with alteplase for acute ischaemic stroke in the Safe Implementation of Thrombolysis in Stroke-Monitoring Study (SITS-MOST): an observational study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of outcome with early stroke treatment: pooled analysis of ATLANTIS, ECASS, and NINDS rt-PA stroke trials.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Pathophysiological topography of acute ischemia by combined diffusion-weighted and perfusion MRI.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Effect of Intravenous Thrombolysis on MRI Parameters and Functional Outcome in Acute Stroke <6 Hours

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Evolution of cerebral infarct volume assessed by diffusion-weighted magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Diffusion- and perfusion-weighted MRI response to thrombolysis in stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Acute human stroke studied by whole brain echo planar diffusion-weighted magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Perfusion thresholds in acute stroke thrombolysis.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Selection of thrombolytic therapy beyond 3 h using magnetic resonance imaging

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Refining the Perfusion–Diffusion Mismatch Hypothesis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Guidelines for the Early Management of Adults With Ischemic Stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

High resolution measurement of cerebral blood flow using intravascular tracer bolus passages. Part I: Mathematical approach and statistical analysis

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The use of PWI and DWI measures in the design of "proof-of-concept" stroke trials.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

The Desmoteplase in Acute Ischemic Stroke Trial (DIAS)

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

New imaging strategies for patient selection for thrombolytic and neuroprotective therapies

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Proof-of-principle phase II MRI studies in stroke: sample size estimates from dichotomous and continuous data.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Dose Escalation of Desmoteplase for Acute Ischemic Stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Type and extent of hemispheric brain infarctions and clinical outcome in early and delayed middle cerebral artery recanalization

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Monitoring intravenous recombinant tissue plasminogen activator thrombolysis for acute ischemic stroke with diffusion and perfusion MRI

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Time Course of Tissue Plasminogen Activator–Induced Recanalization in Acute Cardioembolic Stroke

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Two tales: hemorrhagic transformation but not parenchymal hemorrhage after thrombolysis is related to severity and duration of ischemia: MRI study of acute stroke patients treated with intravenous tissue plasminogen activator within 6 hours.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Outcome and symptomatic bleeding complications of intravenous thrombolysis within 6 hours in MRI-selected stroke patients: comparison of a German multicenter study with the pooled data of ATLANTIS, ECASS, and NINDS tPA trials

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

MRI-based and CT-based thrombolytic therapy in acute stroke within and beyond established time windows: an analysis of 1210 patients.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

MRI versus CT-based thrombolysis treatment within and beyond the 3 h time window after stroke onset: a cohort study.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Comparison of 10 different magnetic resonance perfusion imaging processing methods in acute ischemic stroke: effect on lesion size, proportion of patients with diffusion/perfusion mismatch, clinical scores, and radiologic outcomes.

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Magnetic resonance perfusion diffusion mismatch and thrombolysis in acute ischaemic stroke: a systematic review of the evidence to date

1 reference

https://api.crossref.org/works/10.1016%2FS1474-4422%2808%2970044-9

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1474-4422(08)70044-9

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18296121%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18296121%20AND%20SRC:MED&resulttype=core&format=json

3 January 2020

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