A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition (Q57282418)

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27 April 2020

title

A conditionally immortalized Gli1-positive kidney mesenchymal cell line models myofibroblast transition (English)

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2

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Benjamin D Humphreys

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author name string

Eoghainín Ó hAinmhire

1

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Yoshiharu Muto

3

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Erinn L Donnelly

4

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Flavia G Machado

5

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Lucy X Fan

6

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27 April 2020

Monica Chang-Panesso

7

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language of work or name

English

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publication date

10 October 2018

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American Journal of Physiology - Renal Physiology

27 April 2020

published in

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volume

316

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issue

1

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page(s)

F63-F75

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describes a project that uses

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ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

cites work

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12 December 2020

Direct derivation of conditionally immortal cell lines from an H-2Kb-tsA58 transgenic mouse

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Relationship between renal function and histological changes found in renal-biopsy specimens from patients with persistent glomerular nephritis

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Persistent Infection of a Rat Kidney Cell Line with Rauscher Murine Leukemia Virus

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An increase in the cell component of the cortical interstitium antedates interstitial fibrosis in type 1 diabetic patients

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Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney

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Fate tracing reveals the pericyte and not epithelial origin of myofibroblasts in kidney fibrosis

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A protocol for isolation and culture of mesenchymal stem cells from mouse compact bone

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tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling

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Hedgehog-Gli pathway activation during kidney fibrosis

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Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

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The Terminator mouse is a diphtheria toxin-receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages

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Understanding the origin, activation and regulation of matrix-producing myofibroblasts for treatment of fibrotic disease.

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Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury

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Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

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Insulin-like growth factors and kidney disease

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Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis.

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Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.

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Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

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Pharmacological GLI2 inhibition prevents myofibroblast cell-cycle progression and reduces kidney fibrosis

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12 December 2020

A draft network of ligand-receptor-mediated multicellular signalling in human

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12 December 2020

Pharmacological Inhibition of Focal Adhesion Kinase Attenuates Cardiac Fibrosis in Mice Cardiac Fibroblast and Post-Myocardial-Infarction Models.

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Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells

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The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis.

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12 December 2020

Adventitial MSC-like Cells Are Progenitors of Vascular Smooth Muscle Cells and Drive Vascular Calcification in Chronic Kidney Disease

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12 December 2020

Gli1+ Pericyte Loss Induces Capillary Rarefaction and Proximal Tubular Injury

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12 December 2020

Signaling Crosstalk between Tubular Epithelial Cells and Interstitial Fibroblasts after Kidney Injury

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12 December 2020

Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis

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Mechanisms of Renal Fibrosis.

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

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Anti-Transforming Growth Factor β IgG Elicits a Dual Effect on Calcium Oxalate Crystallization and Progressive Nephrocalcinosis-Related Chronic Kidney Disease.

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12 December 2020

Parabiosis and single-cell RNA sequencing reveal a limited contribution of monocytes to myofibroblasts in kidney fibrosis.

1 reference

12 December 2020

10.1152/AJPRENAL.00460.2018

Identifiers

DOI

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