Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling (Q57269883)

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9 March 2020

title

Nuclear receptor NR4A1 promotes breast cancer invasion and metastasis by activating TGF-β signalling (English)

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9 March 2020

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Tim Johannes Adrianus Dekker

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9 March 2020

Lukas J.A.C. Hawinkels

6

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9 March 2020

Rodney B Luwor

9

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9 March 2020

Peter Devilee

13

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9 March 2020

17

Peter Ten Dijke

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9 March 2020

author name string

FangFang Zhou

1

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9 March 2020

Yvette Drabsch

2

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9 March 2020

Amaya Garcia de Vinuesa

4

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9 March 2020

Yihao Li

5

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9 March 2020

Kelly-Ann Sheppard

7

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9 March 2020

Marie-José Goumans

8

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9 March 2020

Hongjian Zhu

15

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9 March 2020

Long Zhang

16

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9 March 2020

Carlie J de Vries

10

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9 March 2020

Wilma E Mesker

11

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9 March 2020

Rob A E M Tollenaar

12

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9 March 2020

Chris X Lu

14

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9 March 2020

language of work or name

English

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publication date

3 March 2014

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9 March 2020

published in

Nature Communications

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9 March 2020

volume

5

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9 March 2020

issue

1

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page(s)

3388

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https://scigraph.springernature.com/pub.10.1038/ncomms4388

9 March 2020

exact match

0 references

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

The regulation of TGFbeta signal transduction

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS4388

Differentiation plasticity regulated by TGF-beta family proteins in development and disease

21 January 2018

1 reference

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TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

New regulatory mechanisms of TGF-beta receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Smurf1 interacts with transforming growth factor-beta type I receptor through Smad7 and induces receptor degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Arkadia amplifies TGF-beta superfamily signalling through degradation of Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

RNF12 controls embryonic stem cell fate and morphogenesis in zebrafish embryos by targeting Smad7 for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

The dynamic roles of TGF-β in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Nuclear hormone receptors in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCOMMS4388

Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Regulation of Nur77 expression by β-catenin and its mitogenic effect in colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

The mammalian gene collection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Arkadia enhances nodal-related signalling to induce mesendoderm

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Induction of the mammalian node requires Arkadia function in the extraembryonic lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Axin is a scaffold protein in TGF-beta signaling that promotes degradation of Smad7 by Arkadia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Transcriptional activation by Nur77, a growth factor-inducible member of the steroid hormone receptor superfamily

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

TGFbeta signalling: a complex web in cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

TGF-beta-induced epithelial to mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Epithelial-mesenchymal transitions in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

A multigenic program mediating breast cancer metastasis to bone

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Inhibition of pulmonary and skeletal metastasis by a transforming growth factor-beta type I receptor kinase inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Canonical Wnt suppressor, Axin2, promotes colon carcinoma oncogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Axin and GSK3- control Smad3 protein stability and modulate TGF- signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

21 January 2018

Inflammation and cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Strategies for the discovery and development of therapies for metastatic breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

TGF-β-induced epithelial-mesenchymal transition: a link between cancer and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Cancer-related inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

The roles of IFN gamma in protection against tumor development and cancer immunoediting

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Nur77 modulates hepatic lipid metabolism through suppression of SREBP1c activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Zebrafish Dpr2 inhibits mesoderm induction by promoting degradation of nodal receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

GSK3β inactivation induces apoptosis of leukemia cells by repressing the function of c-Myb

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

inferred from DOI database lookup

7 January 2021

based on heuristic

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388

inferred from DOI database lookup

7 January 2021

based on heuristic

Unimpaired thymic and peripheral T cell death in mice lacking the nuclear receptor NGFI-B (Nur77)

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS4388