2-Deoxy-D-ribose-5-phosphate aldolase (DERA): applications and modifications (Q57033544)

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26 April 2020

title

2-Deoxy-D-ribose-5-phosphate aldolase (DERA): applications and modifications (English)

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26 April 2020

author name string

Meera Haridas

series ordinal

1

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26 April 2020

Eman M M Abdelraheem

series ordinal

2

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26 April 2020

Ulf Hanefeld

series ordinal

3

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26 April 2020

language of work or name

English

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publication date

3 October 2018

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Applied Microbiology and Biotechnology

26 April 2020

published in

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volume

102

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26 April 2020

issue

23

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26 April 2020

page(s)

9959-9971

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Creative Commons Attribution 4.0 International

26 April 2020

copyright license

start time

3 October 2018

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Deoxyribose-5-P aldolase: subunit structure and composition of active site lysine region.

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12 December 2020

2-Deoxyribose-5-phosphate aldolase of Salmonella typhimurium: Purification and properties

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Deoxyribose 5-phosphate aldolase. II. Purification and properties of the rat liver enzyme

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12 December 2020

The primary structure of Escherichia coli K12 2-deoxyribose 5-phosphate aldolase. Nucleotide sequence of the deoC gene and the amino acid sequence of the enzyme.

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Rapid evolution of a protein in vitro by DNA shuffling

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Observation of covalent intermediates in an enzyme mechanism at atomic resolution

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Recent Advances in the Chemoenzymatic Synthesis of Carbohydrates and Carbohydrate Mimetics

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12 December 2020

Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase

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12 December 2020

The first crystal structure of archaeal aldolase. Unique tetrameric structure of 2-deoxy-d-ribose-5-phosphate aldolase from the hyperthermophilic archaea Aeropyrum pernix

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12 December 2020

The Direct Catalytic Asymmetric Cross-Aldol Reaction of Aldehydes

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12 December 2020

Microbial production of 2-deoxyribose 5-phosphate from acetaldehyde and triosephosphate for the synthesis of 2'-deoxyribonucleosides

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Construction of deoxyriboaldolase-overexpressing Escherichia coli and its application to 2-deoxyribose 5-phosphate synthesis from glucose and acetaldehyde for 2'-deoxyribonucleoside production

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Enzymatic synthesis and breakdown of desoxyribose phosphate.

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THE MECHANISM OF ACTION OF ALDOLASES. VI. CRYSTALLIZATION OF DEOXYRIBOSE 5-PHOSPHATE ALDOLASE AND THE NUMBER OF ACTIVE SITES.

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THE MECHANISM OF ACTION OF ALDOLASES. VII. FORMATION OF A 2-METHYL-2-DEOXYPENTOSE CATALYZED BY DEOXYRIBOSE 5-PHOSPHATE ALDOLASE

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Deoxyribose aldolase from Lactobacillus plantarum

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12 December 2020

Development of an efficient, scalable, aldolase-catalyzed process for enantioselective synthesis of statin intermediates

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Presence of a novel phosphopentomutase and a 2-deoxyribose 5-phosphate aldolase reveals a metabolic link between pentoses and central carbon metabolism in the hyperthermophilic archaeon Thermococcus kodakaraensis.

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12 December 2020

Structure of aldolase from Thermus thermophilus HB8 showing the contribution of oligomeric state to thermostability

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12 December 2020

Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution

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12 December 2020

Chemoenzymatic synthesis of building blocks for statin side chains

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12 December 2020

Whole organism biocatalysis

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12 December 2020

Organic reactions in aqueous media with a focus on carbon-carbon bond formations: a decade update

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Enantioselective C-C bond synthesis catalysed by enzymes

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Biochemical retrosynthesis of 2'-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase

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Microbial aldolases as C-C bonding enzymes--unknown treasures and new developments

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Directed evolution of an industrial biocatalyst: 2-deoxy-D-ribose 5-phosphate aldolase.

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12 December 2020

Sequential Aldol Condensation Catalyzed by Hyperthermophilic 2-Deoxy-D-Ribose-5-Phosphate Aldolase

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12 December 2020

Catalytic asymmetric aldol reactions in aqueous media

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12 December 2020

Understanding enzyme immobilisation

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12 December 2020

Cloning, expression, and characterization of a new deoxyribose 5-phosphate aldolase from Yersinia sp. EA015.

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12 December 2020

Asymmetric self- and cross-aldol reactions of glycolaldehyde catalyzed by D-fructose-6-phosphate aldolase.

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12 December 2020

Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones

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12 December 2020

Expression and characterization of a novel deoxyribose 5-phosphate aldolase from Paenibacillus sp. EA001.

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12 December 2020

Selection of a new whole cell biocatalyst for the synthesis of 2-deoxyribose 5-phosphate

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12 December 2020

Cloning and characterisation of a new 2-deoxy-d-ribose-5-phosphate aldolase from Rhodococcus erythropolis

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12 December 2020

Amino acid-mediated aldolase immobilisation for enhanced catalysis and thermostability

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12 December 2020

Characterization and application of a newly synthesized 2-deoxyribose-5-phosphate aldolase

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12 December 2020

Aldol reactions mediated by a tetrahedral boronate

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12 December 2020

A highly productive, whole-cell DERA chemoenzymatic process for production of key lactonized side-chain intermediates in statin synthesis

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12 December 2020

DERA is the human deoxyribose phosphate aldolase and is involved in stress response

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12 December 2020

Biosynthesis of 2-deoxysugars using whole-cell catalyst expressing 2-deoxy-D-ribose 5-phosphate aldolase.

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12 December 2020

Trading off stability against activity in extremophilic aldolases.

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12 December 2020

First characterization of extremely halophilic 2-deoxy-D-ribose-5-phosphate aldolase.

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12 December 2020

Redesigning Aldolase Stereoselectivity by Homologous Grafting.

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12 December 2020

Novel Aldo-Keto Reductases for the Biocatalytic Conversion of 3-Hydroxybutanal to 1,3-Butanediol: Structural and Biochemical Studies

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12 December 2020

Immobilization of 2-Deoxy-d-ribose-5-phosphate Aldolase in Polymeric Thin Films via the Langmuir-Schaefer Technique.

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12 December 2020

Probing the acetaldehyde-sensitivity of 2-deoxy-ribose-5-phosphate aldolase (DERA) leads to resistant variants.

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12 December 2020

Biocatalysis for synthesis of pharmaceuticals

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12 December 2020

Biocatalytically Active Thin Films via Self-Assembly of 2-Deoxy-d-ribose-5-phosphate Aldolase-Poly(N-isopropylacrylamide) Conjugates

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12 December 2020

Nucleophile Promiscuity of Natural and Engineered Aldolases.

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12 December 2020

Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products

1 reference

12 December 2020

Conformational Sampling of the Intrinsically Disordered C-Terminal Tail of DERA Is Important for Enzyme Catalysis

1 reference

12 December 2020

Mechanism-based inhibition of an aldolase at high concentrations of its natural substrate acetaldehyde: structural insights and protective strategies

1 reference

12 December 2020

10.1007/S00253-018-9392-8

Identifiers

DOI

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