Bortezomib- and thalidomide-induced peripheral neuropathy in multiple myeloma: clinical and molecular analyses of a phase 3 study (Q56971945)

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13 March 2020

title

Bortezomib- and thalidomide-induced peripheral neuropathy in multiple myeloma: clinical and molecular analyses of a phase 3 study (English)

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13 March 2020

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peripheral neuropathy

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7

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13 March 2020

Marina Martello

8

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Luca Baldini

10

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Iacopo Peccatori

11

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Alessandro Gozzetti

17

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Guido Cavaletti

18

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Michele Cavo

20

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19

Antonio Palumbo

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13 March 2020

author name string

Paola Tacchetti

1

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Carolina Terragna

2

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13 March 2020

Monica Galli

3

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Elena Zamagni

4

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Maria Teresa Petrucci

5

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Annalisa Pezzi

6

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Patrizia Tosi

9

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Miriana Ruggieri

12

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Lucia Pantani

13

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Antonio Lazzaro

14

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Francesca Elice

15

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Serena Rocchi

16

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language of work or name

English

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publication date

17 September 2014

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American Journal of Hematology

13 March 2020

published in

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volume

89

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issue

12

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page(s)

1085-1091

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Neurological aspects of multiple myeloma and related disorders

13 March 2020

cites work

1 reference

Neuropathy in multiple myeloma treated with thalidomide: a prospective study

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1 reference

Characteristics of bortezomib- and thalidomide-induced peripheral neuropathy

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Single-agent bortezomib in previously untreated multiple myeloma: efficacy, characterization of peripheral neuropathy, and molecular correlations with response and neuropathy

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Peripheral neuropathy during bortezomib treatment of multiple myeloma: a review of recent studies

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Management of treatment-emergent peripheral neuropathy in multiple myeloma.

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Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial

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Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial

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Thalidomide in induction treatment increases the very good partial response rate before and after high-dose therapy in previously untreated multiple myeloma

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Short-term thalidomide incorporated into double autologous stem-cell transplantation improves outcomes in comparison with double autotransplantation for multiple myeloma

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Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial.

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Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial.

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Risk factors for, and reversibility of, peripheral neuropathy associated with bortezomib-melphalan-prednisone in newly diagnosed patients with multiple myeloma: subanalysis of the phase 3 VISTA study.

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Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial.

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Thalidomide-induced neuropathy: a ganglionopathy?

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Bortezomib-induced peripheral neuropathy is related to altered levels of brain-derived neurotrophic factor in the peripheral blood of patients with multiple myeloma.

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Bortezomib-induced peripheral neurotoxicity: a neurophysiological and pathological study in the rat.

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Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/bortezomib) cytotoxicity in myeloma cell lines

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Bortezomib induces the formation of nuclear poly(A) RNA granules enriched in Sam68 and PABPN1 in sensory ganglia neurons.

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Immune-mediated neuropathies in myeloma patients treated with bortezomib

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Proteasome inhibitors increase tubulin polymerization and stabilization in tissue culture cells: a possible mechanism contributing to peripheral neuropathy and cellular toxicity following proteasome inhibition.

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Bortezomib alters microtubule polymerization and axonal transport in rat dorsal root ganglion neurons

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Mechanisms of peripheral neuropathy associated with bortezomib and vincristine in patients with newly diagnosed multiple myeloma: a prospective analysis of data from the HOVON-65/GMMG-HD4 trial

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Genetic variation associated with bortezomib-induced peripheral neuropathy

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Genetic factors underlying the risk of thalidomide-related neuropathy in patients with multiple myeloma.

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Genetic factors underlying the risk of bortezomib induced peripheral neuropathy in multiple myeloma patients

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Bortezomib-thalidomide-dexamethasone is superior to thalidomide-dexamethasone as consolidation therapy after autologous hematopoietic stem cell transplantation in patients with newly diagnosed multiple myeloma

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Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised p

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Neurological monitoring reduces the incidence of bortezomib-induced peripheral neuropathy in multiple myeloma patients

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Identifiers

DOI

10.1002/AJH.23835

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25159313%20AND%20SRC:MED&resulttype=core&format=json

13 March 2020

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