Synthesis of carbocyclic nucleosides (Q56864673)

1

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Edouard Suhas

2

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Audrey Farese

3

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Roger Condom

4

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S. Richard Challand

5

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Robert A. Earl

6

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Roger Guedj

Nucleosides. 136. Synthesis and antiviral effects of several 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-alkyluracils. Some structure-activity relationships

7

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publication date

January 1994

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published in

Tetrahedron

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volume

50

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issue

36

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page(s)

10611-10670

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Chemotherapeutic approaches to the treatment of the acquired immune deficiency syndrome (AIDS).

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-ethyluracil. A highly selective antiherpes simplex agent

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Regeneration of the antiviral drug (E)-5-(2-bromovinyl)-2'-deoxyuridine in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Requirements and functions of vesicular stomatitis virus L and NS proteins in the transcription process in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Adenosine analogues as substrates and inhibitors of S-adenosylhomocysteine hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and enzymatic resolution of carbocyclic 2′-ara-fluoro-guanosine: a potent new anti-herpetic agent

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Fluorocarbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluorocarbocyclic 2'-deoxyguanosines

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and anti-HIV activity of carbocyclic 2',3'-didehydro-2',3'-dideoxy 2,6-disubstituted purine nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis of 3-deazaneplanocin A, a powerful inhibitor of S-adenosylhomocysteine hydrolase with potent and selective in vitro and in vivo antiviral activities

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis of two cyclopentenyl-3-deazapyrimidine carbocyclic nucleosides related to cytidine and uridine

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis of potential hypolipidemic agents. Reaction of substituted phenyl 2,3-epoxypropyl ethers with adenine, uracil, and thymine

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and antiviral evaluation of carbocyclic analogues of 2-amino-6-substituted-purine 3'-deoxyribofuranosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and biological evaluation of carbocyclic analogues of lyxofuranosides of 2-amino-6-substituted-purines and 2-amino-6-substituted-8-azapurines

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Stereospecific synthesis and antiviral properties of different enantiomerically pure carbocyclic 2'-deoxyribonucleoside analogues derived from common chiral pools: (+)-(1R,5S)- and (-)-(1S,5R)-2-oxabicyclo[3.3.0]oct-6-en-3-one

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

33. Purines, pyrimidines, and glyoxalines. Part VIII. New syntheses of uracils and thymines

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and antiviral activity of the enantiomeric forms of carba-5-iodo-2'-deoxyuridine and carba-(E)-5-(2-bromovinyl)-2'-deoxyuridine

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbocyclic nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis of chiral carbocyclic nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Approaches to antiviral chemotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

9-[β-DL-2α,3α-Dihydroxy-4β-(hydroxymethyl)- cyclopentyl]adenine, the Carbocyclic Analog of Adenosine1,2

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

S-adenosylhomocysteine hydrolase inhibitors as broad-spectrum antiviral agents

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Correlation between the antiviral activity of acyclic and carbocyclic adenosine analogues in murine L929 cells and their inhibitory effect on L929 cells S-adenosylhomocysteine hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Enantioselective synthesis of the carbocyclic nucleosides (-)-aristeromycin and (-)-neplanocin A by a chemicoenzymatic approach

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbocyclic arabinosyladenine, an adenosine deaminase resistant antiviral agent

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbocyclic analogue of 3-deazaadenosine: a novel antiviral agent using S-adenosylhomocysteine hydrolase as a pharmacological target

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Syntheses of 5'-substituted analogues of carbocyclic 3-deazaadenosine as potential antivirals

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Imino Diels-Alder cycloadditions: An application to the synthesis of (±)-aristeromycin

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Antiviral activities of glycyrrhizin and its modified compounds against human immunodeficiency virus type 1(HIV-1) and herpes simplex virus type 1(HSV-1) in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbocyclic analogs of 5-fluorouracil nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

The mechanism of inhibition of hepatitis B virus replication by the carbocyclic analog of 2′-deoxyguanosine

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Leishmania donovani: in vitro growth inhibition of promastigotes by a carbocyclic analog of 2'-deoxyguanosine

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and antiviral activity of carbocyclic analogs of 2'-deoxyribofuranosides of 2-amino-6-substituted-purines and of 2-amino-6-substituted-8-azapurines

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbocyclic analogues of 5-substituted uracil nucleosides: synthesis and antiviral activity

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and antiviral activity of carbocyclic analogues of xylofuranosides of 2-amino-6-substituted-purines and 2-amino-6-substituted-8-azapurines

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbocyclic analogues of xylofuranosylpurine nucleosides. Synthesis and antitumor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Nucleotides. V. Purine ribonucleoside 2',3'-cyclic carbonates. Preparation and use for the synthesis of 5'-monosubstituted nucleosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Potent and selective activity of a new carbocyclic nucleoside analog (carbovir: NSC 614846) against human immunodeficiency virus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Resolution of racemic carbovir and selective inhibition of human immunodeficiency virus by the (-) enantiomer

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Studies on neplanocin A, new antitumor antibiotic. I. Producing organism, isolation and characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Cyclopentenyluridine and cyclopentenylcytidine analogs as inhibitors of uridine-cytidine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Fluoro carbocyclic nucleosides: synthesis and antiviral activity of 2'- and 6'-fluoro carbocyclic pyrimidine nucleosides including carbocyclic 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-methyluracil and carbocyclic 1-(2-deoxy-2-fluoro-beta-D-ara

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Nucleosides. 129. Synthesis of antiviral nucleosides: 5-alkenyl-1-(2-deoxy-2-fluoro-.beta.-D-arabinofuranosyl)uracils

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Application of Dialkylaminosulfur Trifluorides in the Synthesis of Fluoroorganic Compounds

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Stereospecific 1,2-migrations in carbohydrates. Stereocontrolled synthesis of .alpha.- and .beta.-2-deoxyglycosides

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Oxidation of neplanocin A to the corresponding 3'-keto derivative by S-adenosylhomocysteine hydrolase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Cyclopentenylcytosine. A carbocyclic nucleoside with antitumor and antiviral properties

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Broad-spectrum antiviral and cytocidal activity of cyclopentenylcytosine, a carbocyclic nucleoside targeted at CTP synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Synthesis and antiviral properties of (+/-)-5'-noraristeromycin and related purine carbocyclic nucleosides. A new lead for anti-human cytomegalovirus agent design

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Resolution of 9-(c-4,t-5-bishydroxymethylcyclopent-2-en-r-1-yl)-9H-adenine and selective inhibition of human immunodeficiency virus by the (-) enantiomer

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Synthesis and anti-HIV activity of 9-[c-4,t-5-bis(hydroxymethyl)cyclopent-2-en-r-1-yl]-9H-adenine

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Resolution of aristeromycin enantiomers

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

The enzymatic synthesis of antiviral agents

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Nucleoside Analogues as Chemotherapeutic Agents: A Review

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Antiviral chemotherapy and chemoprophylaxis

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Current progress on nucleoside antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Metabolism and action of purine nucleoside analogs

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Antiviral agents: characteristic activity spectrum depending on the molecular target with which they interact.

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

HIV inhibitors targeted at the reverse transcriptase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Carbovir: the (—) enantiomer is a potent and selective antiviral agent against human immunodeficiency virus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Activities of (-)-carbovir and 3'-azido-3'-deoxythymidine against human immunodeficiency virus in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

7 January 2021

Metabolism of the carbocyclic nucleoside analogue carbovir, an inhibitor of human immunodeficiency virus, in human lymphoid cells

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Perturbation of biochemical transmethylations by 3-deazaadenosine in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Evaluation of synergy between carbovir and 3'-azido-2',3'-deoxythymidine for inhibition of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Adenosine analogs inhibit the guanine-7-methylation of mRNA cap structures

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Effects of adenosine analogues on ATP concentrations in human erythrocytes. Further evidence for a route independent of adenosine kinase

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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Inhibition of HIV-associated reverse transcriptase by sugar-modified derivatives of thymidine 5'-triphosphate in comparison to cellular DNA polymerases alpha and beta

1 reference

https://api.crossref.org/works/10.1016%2FS0040-4020%2801%2989258-9

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