Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH (Q56832411)

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English	Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH	article

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Polymorphic flecainide disposition under conditions of uncontrolled urine flow and pH (English)

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author name string

A S Gross

1

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G Mikus

2

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C Fischer

3

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M Eichelbaum

4

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publication date

1991

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European Journal of Clinical Pharmacology

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40

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2

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155-62

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Resolution of flecainide acetate, N-(2-piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzam ide acetate, and antiarrhythmic properties of the enantiomers

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

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Pharmacokinetics of flecainide in patients with cirrhosis of the liver

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https://pubmed.ncbi.nlm.nih.gov/1906003

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based on heuristic

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The action of flecainide acetate and its enantiomers on mammalian non-myelinated nerve fibres

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https://pubmed.ncbi.nlm.nih.gov/1906003

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based on heuristic

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Pharmacodynamics and side effects of flecainide acetate

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https://pubmed.ncbi.nlm.nih.gov/1906003

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The influence of enzyme induction on polymorphic sparteine oxidation

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

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https://pubmed.ncbi.nlm.nih.gov/1906003

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Oral flecainide pharmacokinetics in patients with impaired renal function

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https://pubmed.ncbi.nlm.nih.gov/1906003

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Stereoselective disposition of flecainide in relation to the sparteine/debrisoquine metaboliser phenotype

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https://pubmed.ncbi.nlm.nih.gov/1906003

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Influence of volume shifts on drug binding during equilibrium dialysis: correction and attenuation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

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Pharmacokinetics of flecainide acetate in patients with severe renal impairment

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophysiological effects of flecainide enantiomers in canine Purkinje fibres

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

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Absence of hepatic cytochrome P450bufI causes genetically deficient debrisoquine oxidation in man

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

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Metabolism of flecainide

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

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Pharmacokinetics of flecainide in patients with mild and moderate renal failure compared with patients with normal renal function

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https://pubmed.ncbi.nlm.nih.gov/1906003

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Flecainide Half-Life Prolongation in 2 Patients with Congestive Heart Failure and Complex Ventricular

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https://pubmed.ncbi.nlm.nih.gov/1906003

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Identification of drug interactions by meta-analysis of premarketing trials: the effect of smoking on the pharmacokinetics and dosage requirements for flecainide acetate

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Determinants of stereospecific binding of type I antiarrhythmic drugs to cardiac sodium channels

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Flecainide enantiomers: disposition in human subjects and electrophysiologic actions in vitro

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https://pubmed.ncbi.nlm.nih.gov/1906003

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Biotransformation and elimination of 14C-flecainide acetate in humans

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https://pubmed.ncbi.nlm.nih.gov/1906003

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The influence of urinary pH on flecainide excretion and its serum pharmacokinetics

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

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Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protein measurement with the Folin phenol reagent

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flecainide pharmacokinetics in healthy volunteers: the influence of urinary pH.

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of the sparteine/debrisoquin phenotype on the disposition of flecainide

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonlinear least-squares regression programs for microcomputers

1 reference

https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

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[Elevated plasma flecainide concentrations in heart failure]

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https://pubmed.ncbi.nlm.nih.gov/1906003

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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