Primary biliary cirrhosis (Q56428273)

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Raoul Poupon

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Marshall Kaplan

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Nora V. Bergasa

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E. Jenny Heathcote

Primary biliary cirrhosis: an orchestrated immune response against epithelial cells

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language of work or name

English

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publication date

11 February 2009

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published in

Hepatology

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volume

50

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page(s)

291-308

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issue

1

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cites work

1 reference

Primary biliary cirrhosis in monozygotic and dizygotic twins: genetics, epigenetics, and environment

21 January 2018

1 reference

Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients

21 January 2018

1 reference

Induction of primary biliary cirrhosis in guinea pigs following chemical xenobiotic immunization

21 January 2018

1 reference

Epitope mapping and reactivity of autoantibodies to the E2 component of 2-oxoglutarate dehydrogenase complex in primary biliary cirrhosis using recombinant 2-oxoglutarate dehydrogenase complex.

21 January 2018

1 reference

Mucosal immunity and primary biliary cirrhosis: presence of antimitochondrial antibodies in urine

21 January 2018

1 reference

A sensitive bead assay for antimitochondrial antibodies: Chipping away at AMA-negative primary biliary cirrhosis

21 January 2018

1 reference

Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis

21 January 2018

1 reference

Identification and precursor frequency analysis of a common T cell epitope motif in mitochondrial autoantigens in primary biliary cirrhosis

21 January 2018

1 reference

Geotherapeutics of primary biliary cirrhosis: bright and sunny around the Mediterranean but still cloudy and foggy in the United Kingdom

21 January 2018

1 reference

Natural history of early primary biliary cirrhosis

21 January 2018

1 reference

Characterization of antimitochondrial antibodies in health adults

21 January 2018

1 reference

Survival and symptom progression in a geographically based cohort of patients with primary biliary cirrhosis: follow-up for up to 28 years

21 January 2018

1 reference

The effect of ursodeoxycholic acid therapy on liver fibrosis progression in primary biliary cirrhosis

21 January 2018

1 reference

Excellent long-term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid

21 January 2018

1 reference

Ursodiol for the long-term treatment of primary biliary cirrhosis. The UDCA-PBC Study Group.

21 January 2018

1 reference

Combined analysis of randomized controlled trials of ursodeoxycholic acid in primary biliary cirrhosis

21 January 2018

1 reference

Combined analysis of the effect of treatment with ursodeoxycholic acid on histologic progression in primary biliary cirrhosis

21 January 2018

1 reference

The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis

21 January 2018

1 reference

Primary biliary cirrhosis: incidence and predictive factors of cirrhosis development in ursodiol-treated patients

21 January 2018

1 reference

Prognosis in primary biliary cirrhosis: model for decision making

21 January 2018

1 reference

Extramural cross-validation of the Mayo primary biliary cirrhosis survival model establishes its generalizability

21 January 2018

1 reference

Biochemical markers of liver fibrosis and lymphocytic piecemeal necrosis in UDCA-treated patients with primary biliary cirrhosis

21 January 2018

1 reference

Anti-gp210 and anti-centromere antibodies are different risk factors for the progression of primary biliary cirrhosis

21 January 2018

1 reference

When is liver biopsy needed in the diagnosis of primary biliary cirrhosis?

21 January 2018

1 reference

Assessment of biliary fibrosis by transient elastography in patients with PBC and PSC.

21 January 2018

1 reference

The true impact of fatigue in primary biliary cirrhosis: a population study

21 January 2018

1 reference

Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort

21 January 2018

1 reference

Fatigue and primary biliary cirrhosis: association of globus pallidus magnetisation transfer ratio measurements with fatigue severity and blood manganese levels.

21 January 2018

1 reference

Quality of life in patients with primary biliary cirrhosis

21 January 2018

1 reference

Four year follow up of fatigue in a geographically defined primary biliary cirrhosis patient cohort

21 January 2018

1 reference

Primary biliary cirrhosis: report of a focus study group

21 January 2018

1 reference

Natural history of pruritus in primary biliary cirrhosis

21 January 2018

1 reference

Natural history of primary biliary cirrhosis.

21 January 2018

1 reference

The pruritus of cholestasis: from bile acids to opiate agonists

21 January 2018

1 reference

Long-term outcome after partial external biliary diversion for intractable pruritus in patients with intrahepatic cholestasis

21 January 2018

1 reference

Effect of distal splenorenal shunt on survival of patients with primary biliary cirrhosis

21 January 2018

1 reference

Management of osteoporosis, fat-soluble vitamin deficiencies, and hyperlipidemia in primary biliary cirrhosis

21 January 2018

1 reference

Bone disease in primary biliary cirrhosis: independent indicators and rate of progression.

21 January 2018

1 reference

Longitudinal bone loss in postmenopausal women with primary biliary cirrhosis and well-preserved liver function.

21 January 2018

1 reference

Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice

21 January 2018

1 reference

Reduced serum lipoprotein(a) levels in patients with primary biliary cirrhosis.

21 January 2018

1 reference

Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis

21 January 2018

1 reference

Hypercholesterolemia and atherosclerosis in primary biliary cirrhosis: what is the risk?

21 January 2018

1 reference

Hypercholesterolaemia is not associated with early atherosclerotic lesions in primary biliary cirrhosis

21 January 2018

1 reference

Fat-soluble vitamin levels in patients with primary biliary cirrhosis

21 January 2018

1 reference

Vitamin E deficiency in primary biliary cirrhosis: gastrointestinal malabsorption, frequency and relationship to other lipid-soluble vitamins.

21 January 2018

1 reference

The autoepitope of the 74-kD mitochondrial autoantigen of primary biliary cirrhosis corresponds to the functional site of dihydrolipoamide acetyltransferase

21 January 2018

1 reference

Antimitochondrial antibody negative primary biliary cirrhosis: a distinct syndrome of autoimmune cholangitis

21 January 2018

1 reference

Detection of antimitochondrial autoantibodies in immunofluorescent AMA-negative patients with primary biliary cirrhosis using recombinant autoantigens

21 January 2018

1 reference

Antimitochondrial antibody negative primary biliary cirrhosis in Japan: utilization of clinical data when patients applied to receive public financial aid.

21 January 2018

1 reference

Review article: is there an optimal therapeutic regimen for antimitochondrial antibody-negative primary biliary cirrhosis (autoimmune cholangitis)?

21 January 2018

1 reference

Development of autoimmune hepatitis in primary biliary cirrhosis.

21 January 2018

1 reference

International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis

21 January 2018

1 reference

Characterization of the overlap syndrome of primary biliary cirrhosis (PBC) and autoimmune hepatitis: evidence for it being a hepatitic form of PBC in genetically susceptible individuals

21 January 2018

1 reference

Primary biliary cirrhosis with additional features of autoimmune hepatitis: response to therapy with ursodeoxycholic acid

21 January 2018

1 reference

Overlap of autoimmune hepatitis and primary biliary cirrhosis: long-term outcomes.

21 January 2018

1 reference

Long term outcome and response to therapy of primary biliary cirrhosis-autoimmune hepatitis overlap syndrome

21 January 2018

1 reference

Consecutive occurrence of primary biliary cirrhosis and autoimmune hepatitis: a case report and review of the literature

21 January 2018

1 reference

Diagnostic and therapeutic implications of bile duct injury in autoimmune hepatitis

21 January 2018

1 reference

Applicability of the IAIHG scoring system to the diagnosis of antimitochondrial/anti-M2 seropositive variant form of autoimmune hepatitis.

21 January 2018

1 reference

Long-term follow-up of antimitochondrial antibody-positive autoimmune hepatitis

21 January 2018

1 reference

Randomised controlled trials of ursodeoxycholic-acid therapy for primary biliary cirrhosis: a meta-analysis

21 January 2018

1 reference

Ursodeoxycholic acid for patients with primary biliary cirrhosis: an updated systematic review and meta-analysis of randomized clinical trials using Bayesian approach as sensitivity analyses

21 January 2018

1 reference

Transplantation trends in primary biliary cirrhosis.

21 January 2018

1 reference

Characterisation of patients with a complete biochemical response to ursodeoxycholic acid

21 January 2018

1 reference

Utilization of the Mayo risk score in patients with primary biliary cirrhosis receiving ursodeoxycholic acid

21 January 2018

1 reference

Treatment with ursodeoxycholic acid is associated with weight gain in patients with primary biliary cirrhosis

21 January 2018

1 reference

Double blind controlled trial of d-penicillamine in patients with primary biliary cirrhosis

21 January 2018

1 reference

Ten-year combination treatment with colchicine and ursodeoxycholic acid for primary biliary cirrhosis: a double-blind, placebo-controlled trial on symptomatic patients.

21 January 2018

1 reference

Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis

21 January 2018

1 reference

Incomplete response to ursodeoxycholic acid in primary biliary cirrhosis: is a double dosage worthwhile?

21 January 2018

1 reference

Silymarin in the treatment of patients with primary biliary cirrhosis with a suboptimal response to ursodeoxycholic acid.

21 January 2018

1 reference

A randomized controlled trial of colchicine plus ursodiol versus methotrexate plus ursodiol in primary biliary cirrhosis: ten-year results

21 January 2018

1 reference

Fenofibrate treatment in patients with primary biliary cirrhosis

21 January 2018

1 reference

A randomized, controlled crossover trial of ondansetron in patients with primary biliary cirrhosis and fatigue

21 January 2018

1 reference

Fluoxetine for the treatment of fatigue in primary biliary cirrhosis: a randomized, double-blind controlled trial.

21 January 2018

1 reference

Fatigue in primary biliary cirrhosis is associated with excessive daytime somnolence.

21 January 2018

1 reference

Modafinil for excessive sleepiness associated with shift-work sleep disorder

21 January 2018

1 reference

The efficacy and safety of bile Acid binding agents, opioid antagonists, or rifampin in the treatment of cholestasis-associated pruritus

21 January 2018

1 reference

Extracorporeal albumin dialysis: a procedure for prolonged relief of intractable pruritus in patients with primary biliary cirrhosis

21 January 2018

1 reference

Effect of rifampicin treatment on hepatic drug metabolism and serum bile acids in patients with primary biliary cirrhosis.

21 January 2018

1 reference

Comparison of rifampicin with phenobarbitone for treatment of pruritus in biliary cirrhosis.

21 January 2018

1 reference

Treatment of pruritus of primary biliary cirrhosis with rifampin

21 January 2018

1 reference

Assessing the quality of reports of randomized clinical trials: is blinding necessary?

21 January 2018

1 reference

Hepatitis and liver dysfunction with rifampicin therapy for pruritus in primary biliary cirrhosis.

21 January 2018

1 reference

Rifampin-induced selective serotonin reuptake inhibitor withdrawal syndrome in a patient treated with sertraline

21 January 2018

1 reference

The incidence of pruritus after epidural morphine.

21 January 2018

1 reference

The pruritus of cholestasis: potential pathogenic and therapeutic implications of opioids

21 January 2018

1 reference

Opioid peptides and primary biliary cirrhosis

21 January 2018

1 reference

Effect of oral naltrexone on pruritus in cholestatic patients

21 January 2018

1 reference

Pruritus and fatigue associated with liver disease: is there a role for ondansetron?

21 January 2018

1 reference

Paroxetine in the treatment of severe non-dermatological pruritus: a randomized, controlled trial

21 January 2018

1 reference

Itch in primary biliary cirrhosis: a patients' perspective

21 January 2018

1 reference

Antihistamines in dermatology

21 January 2018

1 reference

Topical ciclosporin in the treatment of ocular surface disorders

21 January 2018

1 reference

Conventional therapy of Sjogren's syndrome

21 January 2018

1 reference

Increased prevalence of antimitochondrial antibodies in first-degree relatives of patients with primary biliary cirrhosis

21 January 2018

1 reference

Hepatocellular carcinoma in primary biliary cirrhosis and its impact on outcomes

21 January 2018

1 reference

Incidence of cancer in primary biliary cirrhosis: the Mayo experience

21 January 2018

1 reference

Management of hepatocellular carcinoma

21 January 2018

1 reference

Prevalence and predictors of esophageal varices in patients with primary biliary cirrhosis

21 January 2018

1 reference

Which patients with primary biliary cirrhosis or primary sclerosing cholangitis should undergo endoscopic screening for oesophageal varices detection?

21 January 2018

1 reference

Portal hypertension in primary biliary cirrhosis

21 January 2018

1 reference

Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosis

21 January 2018

1 reference

Alendronate improves bone mineral density in primary biliary cirrhosis: a randomized placebo-controlled trial

21 January 2018

1 reference

Simvastatin in primary biliary cirrhosis: effects on serum lipids and distinct disease markers

21 January 2018

1 reference

Primary biliary cirrhosis, hyperlipidemia, and atherosclerotic risk: a systematic review

21 January 2018

1 reference

Statins and hepatotoxicity: focus on patients with fatty liver

21 January 2018

1 reference

Long-term fibrate treatment for PBC.

21 January 2018

1 reference

Recurrence of primary biliary cirrhosis after liver transplantation: Histologic estimate of incidence and natural history

21 January 2018

1 reference

Long-term survival and impact of ursodeoxycholic acid treatment for recurrent primary biliary cirrhosis after liver transplantation

21 January 2018

1 reference

Immunosuppression affects the rate of recurrent primary biliary cirrhosis after liver transplantation

21 January 2018

1 reference

Fracture risk of women with primary biliary cirrhosis: no increase compared with general population controls

21 January 2018

1 reference

Osteoporosis in Primary Biliary Cirrhosis: A Randomized Trial of the Efficacy and Feasibility of Estrogen/Progestin

21 January 2018

1 reference

Effect of liver cirrhosis on the systemic availability of naltrexone in humans

21 January 2018

1 reference

American Gastroenterological Association policy statement on the use of medical practice guidelines by managed care organizations and insurance carriers

21 January 2018

1 reference

7 January 2021

Primary biliary cirrhosis

1 reference

7 January 2021

Major histocompatibility complex class-II alleles in primary biliary cirrhosis

1 reference

7 January 2021

Increased prevalence of primary biliary cirrhosis near Superfund toxic waste sites

1 reference

7 January 2021

Familial primary biliary cirrhosis reassessed: a geographically-based population study

1 reference

7 January 2021

Primary biliary cirrhosis: survival of a large cohort of symptomatic and asymptomatic patients followed for 24 years

1 reference

7 January 2021

Primary biliary cirrhosis: clinical features and outcome, with special reference to asymptomatic disease

1 reference

7 January 2021

Azathioprine and prognosis in primary biliary cirrhosis.

1 reference

7 January 2021

The prognostic importance of clinical and histologic features in asymptomatic and symptomatic primary biliary cirrhosis

1 reference

7 January 2021

Time course of histological progression in primary biliary cirrhosis

1 reference

7 January 2021

Prospective evaluation of esophageal varices in primary biliary cirrhosis: development, natural history, and influence on survival

1 reference

7 January 2021

Long-term ursodeoxycholic acid delays histological progression in primary biliary cirrhosis

1 reference

7 January 2021

Effects of ursodeoxycholic acid on survival in patients with primary biliary cirrhosis

1 reference

7 January 2021

A multicenter, controlled trial of ursodiol for the treatment of primary biliary cirrhosis. UDCA-PBC Study Group

1 reference

7 January 2021

Ten-year survival in ursodeoxycholic acid-treated patients with primary biliary cirrhosis. The UDCA-PBC Study Group

1 reference

7 January 2021

A placebo-controlled trial of primary biliary cirrhosis treatment with colchicine and ursodeoxycholic acid

1 reference

7 January 2021

Clinical and biochemical expression of the histopathological lesions of primary biliary cirrhosis. UDCA-PBC Group

1 reference

7 January 2021

Histopathological study of primary biliary cirrhosis and the effect of ursodeoxycholic acid treatment on histology progression

1 reference

7 January 2021

Depression in patients with primary biliary cirrhosis and primary sclerosing cholangitis

1 reference

7 January 2021

Increased incidence of hypothyroidism in primary biliary cirrhosis

1 reference

7 January 2021

Vitamin D-receptor genotypes as independent genetic predictors of decreased bone mineral density in primary biliary cirrhosis

1 reference

7 January 2021

Severity of cholestasis and advanced histological stage but not menopausal status are the major risk factors for osteoporosis in primary biliary cirrhosis

1 reference

7 January 2021

Bone loss and reduced osteoblast function in primary biliary cirrhosis

1 reference

7 January 2021

Fat-Soluble Vitamin Nutriture in primary Biliary Cirrhosis

1 reference

7 January 2021

Pathogenesis of steatorrhea in primary biliary cirrhosis

1 reference

7 January 2021

Vitamin E deficiency and its clinical significance in adults with primary biliary cirrhosis and other forms of chronic liver disease

1 reference

7 January 2021

Comparison of the clinical features and clinical course of antimitochondrial antibody-positive and -negative primary biliary cirrhosis

1 reference

7 January 2021

Primary biliary cirrhosis-autoimmune hepatitis overlap syndrome: clinical features and response to therapy

1 reference

7 January 2021

Overlap syndrome of primary biliary cirrhosis and autoimmune hepatitis: a retrospective study of 115 cases of autoimmune liver disease

1 reference

7 January 2021

Autoimmune cholangiopathy: the result of consecutive primary biliary cirrhosis and autoimmune hepatitis?

1 reference

7 January 2021

Development of autoimmune hepatitis in patients with typical primary biliary cirrhosis

1 reference

7 January 2021

Comparison of three doses of ursodeoxycholic acid in the treatment of primary biliary cirrhosis: a randomized trial

1 reference

7 January 2021

Bioavailability of four ursodeoxycholic acid preparations

1 reference

7 January 2021

Effect of ursodeoxycholic acid on serum lipids of patients with primary biliary cirrhosis

1 reference

7 January 2021

Randomized trial of chlorambucil for primary biliary cirrhosis.

1 reference

7 January 2021

Trial of penicillamine in advanced primary biliary cirrhosis

1 reference

7 January 2021

A controlled trial of cyclosporine in the treatment of primary biliary cirrhosis

1 reference

7 January 2021

Cyclosporin A treatment in primary biliary cirrhosis: results of a long-term placebo controlled trial

1 reference

7 January 2021

A controlled trial of prednisolone treatment in primary biliary cirrhosis. Three-year results

1 reference

7 January 2021

Low-dose methotrexate is ineffective in primary biliary cirrhosis: long-term results of a placebo-controlled trial

1 reference

7 January 2021

A prospective trial of colchicine for primary biliary cirrhosis

1 reference

7 January 2021

Oral budesonide in the treatment of patients with primary biliary cirrhosis with a suboptimal response to ursodeoxycholic acid

1 reference

7 January 2021

Relief from profound fatigue associated with chronic liver disease by long-term ondansetron therapy

1 reference

7 January 2021

Modafinil for the treatment of fatigue in primary biliary cirrhosis

1 reference

7 January 2021

An open study of modafinil for the treatment of daytime somnolence and fatigue in primary biliary cirrhosis

1 reference

7 January 2021

The treatment of pruritus and hypercholesteremia of primary biliary cirrhosis with cholestyramine

1 reference

7 January 2021

Treatment of severe refractory pruritus with fractionated plasma separation and adsorption (Prometheus)

1 reference

7 January 2021

Plasma separation and anion adsorption transiently relieve intractable pruritus in primary biliary cirrhosis

1 reference

7 January 2021

Rifampin is safe for treatment of pruritus due to chronic cholestasis: a meta-analysis of prospective randomized-controlled trials

1 reference

7 January 2021

Effects of naloxone infusions in patients with the pruritus of cholestasis. A double-blind, randomized, controlled trial

1 reference

7 January 2021

Oral naltrexone treatment for cholestatic pruritus: A double-blind, placebo-controlled study

1 reference

7 January 2021

Oral nalmefene therapy reduces scratching activity due to the pruritus of cholestasis: a controlled study

1 reference

7 January 2021

Efficacy and safety of oral naltrexone treatment for pruritus of cholestasis, a crossover, double blind, placebo-controlled study

1 reference

7 January 2021

Open-label trial of oral nalmefene therapy for the pruritus of cholestasis

1 reference

7 January 2021

Naltrexone in the treatment of alcohol dependence

1 reference

7 January 2021

Naltrexone and hepatotoxicity

1 reference

7 January 2021

Pain as a complication of use of opiate antagonists for symptom control in cholestasis

1 reference

7 January 2021

Ondansetron for pruritus due to cholestasis

1 reference

7 January 2021

Improvement of cholestatic pruritus by ondansetron

1 reference

7 January 2021

Sertraline as a first-line treatment for cholestatic pruritus

1 reference

7 January 2021

Liver transplantation for intractable pruritus is contraindicated before an adequate trial of opiate antagonist therapy

1 reference

7 January 2021

Primary biliary cirrhosis. Sole presentation with rampant dental caries

1 reference

7 January 2021

Primary biliary cirrhosis, sicca complex, and dysphagia

1 reference

7 January 2021

Clinical predictors for hepatocellular carcinoma in patients with primary biliary cirrhosis

1 reference

7 January 2021

Liver transplantation in precirrhotic biliary tract disease: Portal hypertension is frequently associated with nodular regenerative hyperplasia and obliterative portal venopathy

1 reference

7 January 2021

Etidronate for osteoporosis in primary biliary cirrhosis: a randomized trial

1 reference

7 January 2021

Lipoprotein pattern and plasma lipoprotein lipase activities in patients with primary biliary cirrhosis. Relationship with increase of HDL2 fraction in Lp-X-positive and Lp-X-negative subjects

1 reference

7 January 2021