Stealth® liposomes: from theory to product (Q56141225)

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Peter M. Frederik

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Joseph J. Vallner

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Danilo D. Lasic

Advanced Drug Delivery Reviews

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language of work or name

English

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publication date

March 1997

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published in

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volume

24

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page(s)

165-177

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issue

2-3

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cites work

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Surface properties of acidic phospholipids: interaction of monolayers and hydrated liquid crystals with uni- and bi-valent metal ions.

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The phospholipid component of small unilamellar liposomes controls the rate of clearance of entrapped solutes from the circulation

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Sterically stabilized liposomes: a hypothesis on the molecular origin of the extended circulation times

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Gelation of liposome interior. A novel method for drug encapsulation

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Transmembrane ammonium sulfate gradients in liposomes produce efficient and stable entrapment of amphipathic weak bases

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Transmembrane gradient driven phase transitions within vesicles: lessons for drug delivery

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Fluorinated phosphatidylcholine-based liposomes: H+/Na+ permeability, active doxorubicin encapsulation and stability, in human serum

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Poly(ethylene glycol) on the liposome surface: on the mechanism of polymer-coated liposome longevity

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Characterization of the brush regime for grafted polymer layers at the solid-liquid interface

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Modulation of interaction forces between bilayers exposing short-chained ethylene oxide headgroups

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New amphipatic polymer-lipid conjugates forming long-circulating reticuloendothelial system-evading liposomes.

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Amphiphilic vinyl polymers effectively prolong liposome circulation time in vivo

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Interbilayer transfer of phospholipid-anchored macromolecules via monomer diffusion

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Insertion of poly(ethylene glycol) derivatized phospholipid into pre-formed liposomes results in prolonged in vivo circulation time

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Specific targeting with poly(ethylene glycol)-modified liposomes: coupling of homing devices to the ends of the polymeric chains combines effective target binding with long circulation times

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Attachment of antibodies to sterically stabilized liposomes: evaluation, comparison and optimization of coupling procedures

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Range and magnitude of the steric pressure between bilayers containing phospholipids with covalently attached poly(ethylene glycol).

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Surface Potential of Lipid Monolayers with Grafted Polyethylene Glycols

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Interaction of poly(ethylene-glycols) with air-water interfaces and lipid monolayers: investigations on surface pressure and surface potential

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Sterically stabilized liposomes. Reduction in electrophoretic mobility but not electrostatic surface potential

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Sterically stabilized liposomes: physical and biological properties

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Determination of the thickness of the fixed aqueous layer around polyethyleneglycol-coated liposomes

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Interfacial thickness of liposomes containing poly(ethylene glycol)-cholesterol from electrophoresis

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Pharmacokinetics and antitumor activity of epirubicin encapsulated in long-circulating liposomes incorporating a polyethylene glycol-derivatized phospholipid

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Targetability of novel immunoliposomes modified with amphipathic poly(ethylene glycol)s conjugated at their distal terminals to monoclonal antibodies

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