A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target. (Q55463442)

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English	A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target.	scientific article

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21 January 2020

A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target (English)

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21 January 2020

Alexander Schulte

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21 January 2020

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Zora Modrusan

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21 January 2020

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Hauke S Günther

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21 January 2020

Heidi S Phillips

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21 January 2020

Dirk Kemming

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21 January 2020

Tobias Martens

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21 January 2020

Samir Kharbanda

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21 January 2020

Robert H Soriano

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21 January 2020

Svenja Zapf

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21 January 2020

Manfred Westphal

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21 January 2020

Katrin Lamszus

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21 January 2020

publication date

3 February 2011

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21 January 2020

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21 January 2020

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21 January 2020

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21 January 2020

590-602

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21 January 2020

Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons

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21 January 2018

NCBI GEO: mining tens of millions of expression profiles--database and tools update

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21 January 2018

CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

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Daoy medulloblastoma cells that express CD133 are radioresistant relative to CD133- cells, and the CD133+ sector is enlarged by hypoxia

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Glioblastoma subclasses can be defined by activity among signal transduction pathways and associated genomic alterations

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Insight into the complex regulation of CD133 in glioma

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A hierarchy of self-renewing tumor-initiating cell types in glioblastoma.

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Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells

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The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids.

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Mouse serum factor(s) down-modulate the CD4 and CXCR4 molecules on human T cells conferring resistance to HIV infection in NOG mice.

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Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration

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CXCR4 mediates the proliferation of glioblastoma progenitor cells

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CXCR4 expression mediates glioma cell invasiveness

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Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4

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21 January 2018

Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival.

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Signalling pathways involved in the chemotactic activity of CXCL12 in cultured rat cerebellar neurons and CHP100 neuroepithelioma cells.

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21 January 2018

Gene expression profiling of gliomas strongly predicts survival

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

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21 January 2018

CD133 is a marker of bioenergetic stress in human glioma

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21 January 2018

Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria

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21 January 2018

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

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Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection.

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Targeting brain cancer: advances in the molecular pathology of malignant glioma and medulloblastoma

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Directed migration of neural stem cells to sites of CNS injury by the stromal cell-derived factor 1alpha/CXC chemokine receptor 4 pathway

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21 January 2018

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

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21 January 2018

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

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Inhibition of glioblastoma growth in a highly invasive nude mouse model can be achieved by targeting epidermal growth factor receptor but not vascular endothelial growth factor receptor-2.

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CXCR4 signaling in the regulation of stem cell migration and development

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Collagens, integrins and the mesenchymal drift in glioblastomas: A comparison of biopsy specimens, spheroid and early monolayer cultures

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

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Influence of oxygen tension on CD133 phenotype in human glioma cell cultures.

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A small-molecule antagonist of CXCR4 inhibits intracranial growth of primary brain tumors.

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Cancer stem cells as mediators of treatment resistance in brain tumors: status and controversies

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Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype.

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CXCL12 in malignant glial tumors: a possible role in angiogenesis and cross-talk between endothelial and tumoral cells.

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Sequential processing of the transmembrane chemokines CX3CL1 and CXCL16 by alpha- and gamma-secretases

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CXCR-4, a chemokine receptor, is overexpressed in and required for proliferation of glioblastoma tumor cells.

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Identification of human brain tumour initiating cells

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Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1alpha.

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CXCR4 expression is elevated in glioblastoma multiforme and correlates with an increase in intensity and extent of peritumoral T2-weighted magnetic resonance imaging signal abnormalities

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Localization of CXCR4 in the forebrain of the adult rat.

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Karyotype analyses of 20 human glioma cell lines

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LRRC4 inhibits human glioblastoma cells proliferation, invasion, and proMMP-2 activation by reducing SDF-1 alpha/CXCR4-mediated ERK1/2 and Akt signaling pathways

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Hypoxia- and vascular endothelial growth factor-induced stromal cell-derived factor-1alpha/CXCR4 expression in glioblastomas: one plausible explanation of Scherer's structures.

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Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion

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A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia.

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7 January 2021

based on heuristic

inferred from DOI database lookup

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