Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis. (Q55054144)

16 June 2018

title

Excessive activity of apolipoprotein B mRNA editing enzyme catalytic polypeptide 2 (APOBEC2) contributes to liver and lung tumorigenesis. (English)

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16 June 2018

author

Yoshihide Ueda

4

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Tsutomu Chiba

8

object named as

Tsutomu Chiba

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author name string

Shunsuke Okuyama

1

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Hiroyuki Marusawa

2

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Tomonori Matsumoto

3

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Yuko Matsumoto

5

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Yoko Endo

6

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Atsushi Takai

7

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language of work or name

English

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publication date

30 May 2011

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International Journal of Cancer

published in

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volume

130

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page(s)

1294-1301

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issue

6

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Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business

cites work

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Advantages and disadvantages of cytidine deamination

21 January 2018

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Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases.

21 January 2018

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Adaptive evolution and antiviral activity of the conserved mammalian cytidine deaminase APOBEC3H.

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Reward versus risk: DNA cytidine deaminases triggering immunity and disease

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Apolipoprotein B-48 is the product of a messenger RNA with an organ-specific in-frame stop codon.

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A novel form of tissue-specific RNA processing produces apolipoprotein-B48 in intestine

21 January 2018

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Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

21 January 2018

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The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA

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DNA deamination mediates innate immunity to retroviral infection

21 January 2018

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The enzymatic activity of CEM15/Apobec-3G is essential for the regulation of the infectivity of HIV-1 virion but not a sole determinant of its antiviral activity.

21 January 2018

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APOBEC family proteins: novel antiviral innate immunity

21 January 2018

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G to A hypermutation of hepatitis B virus.

21 January 2018

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Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo

21 January 2018

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Dual effect of APOBEC3G on Hepatitis B virus

21 January 2018

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Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

21 January 2018

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Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

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APOBEC-2, a cardiac- and skeletal muscle-specific member of the cytidine deaminase supergene family

21 January 2018

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Mice deficient in APOBEC2 and APOBEC3.

21 January 2018

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Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals

21 January 2018

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A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme

21 January 2018

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Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression

21 January 2018

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Constitutive expression of AID leads to tumorigenesis

21 January 2018

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Expression of APOBEC2 is transcriptionally regulated by NF-kappaB in human hepatocytes.

21 January 2018

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Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

21 January 2018

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Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.

21 January 2018

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Notch signalling via RBP-J promotes myeloid differentiation.

21 January 2018

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Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling

21 January 2018

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De novo protein synthesis is required for the activation-induced cytidine deaminase function in class-switch recombination

21 January 2018

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Identification of the activation-induced cytidine deaminase gene from zebrafish: an evolutionary analysis

21 January 2018

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Cloning and expression of the AID gene in the channel catfish

21 January 2018

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The APOBEC-2 crystal structure and functional implications for the deaminase AID

21 January 2018

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The transcripts of SFRP1,CEP63 and EIF4G2 genes are frequently downregulated in transitional cell carcinomas of the bladder

21 January 2018

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Tenets of PTEN tumor suppression

21 January 2018

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Anti-viral protein APOBEC3G is induced by interferon-alpha stimulation in human hepatocytes.

21 January 2018

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Interferon-inducible expression of APOBEC3 editing enzymes in human hepatocytes and inhibition of hepatitis B virus replication

21 January 2018

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High expression of APOBEC3G in patients infected with hepatitis C virus

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Hepatocellular carcinoma

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Deficiency in APOBEC2 leads to a shift in muscle fiber type, diminished body mass, and myopathy

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/IJC.26114

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16 June 2018

PubMed ID

21469143

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16 June 2018