NYH/187/162 (Q54931215)

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cell line

NYH/187

Language	Label	Description	Also known as
English	NYH/187/162	cell line	NYH/187

Statements

1 reference

Cellosaurus release 44

27 January 2023

cancer cell line

1 reference

Cellosaurus release 44

27 January 2023

parent cell line

1 reference

Cellosaurus release 44

27 January 2023

described by source

Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform

1 reference

Cellosaurus release 44

27 January 2023

Human small cell lung cancer NYH cells resistant to the bisdioxopiperazine ICRF-187 exhibit a functional dominant Tyr165Ser mutation in the Walker A ATP binding site of topoisomerase II alpha.

1 reference

Cellosaurus release 44

27 January 2023

established from medical condition

lung small cell carcinoma

1 reference

Cellosaurus release 44

27 January 2023

derived from organism type

1 reference

Cellosaurus release 44

27 January 2023

Identifiers

1 reference

Cellosaurus release 44

27 January 2023

Sitelinks

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