The ROCK inhibitor Y-27632 negatively affects the expansion/survival of both fresh and cryopreserved cord blood-derived CD34+ hematopoietic progenitor cells: Y-27632 negatively affects the expansion/survival of CD34+HSPCs. (Q54690725)

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scientific article published in June 2010

Language	Label	Description	Also known as
English	The ROCK inhibitor Y-27632 negatively affects the expansion/survival of both fresh and cryopreserved cord blood-derived CD34+ hematopoietic progenitor cells: Y-27632 negatively affects the expansion/survival of CD34+HSPCs.	scientific article published in June 2010

Statements

scholarly article

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

The ROCK inhibitor Y-27632 negatively affects the expansion/survival of both fresh and cryopreserved cord blood-derived CD34+ hematopoietic progenitor cells: Y-27632 negatively affects the expansion/survival of CD34+HSPCs. (English)

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

cryopreservation

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3

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

author name string

Clara Bueno

1

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

Rosa Montes

2

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

publication date

1 June 2010

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

Stem Cell Reviews and Reports

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

6

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Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

215-223

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Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

2

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

https://scigraph.springernature.com/pub.10.1007/s12015-010-9118-5

0 references

ROCK inhibitor improves survival of cryopreserved serum/feeder-free single human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retroviral transduction of hematopoietic cells differentiated from human embryonic stem cell-derived CD45(neg)PFV hemogenic precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NG2 antigen is expressed in CD34+ HPCs and plasmacytoid dendritic cell precursors: is NG2 expression in leukemia dependent on the target cell where leukemogenesis is triggered?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved postthaw viability and in vitro functionality of peripheral blood hematopoietic progenitor cells after cryopreservation with a theoretically optimized freezing curve

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-bone marrow transplantation of human CD34(+) cells into NOD/LtSz-scid IL-2rgamma(null) mice permits multilineage engraftment without previous irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human embryonic stem cells: potential tool for achieving immunotolerance?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cord blood transplantation: state of the art.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The composition of leukapheresis products impacts on the hematopoietic recovery after autologous transplantation independently of the mobilization regimen

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mobilization of peripheral blood progenitor cells with a combination of cyclophosphamide, r-metHuSCF and filgrastim in patients with breast cancer previously treated with chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cryopreservation of hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the Rho/ROCK pathway reduces apoptosis during transplantation of embryonic stem cell-derived neural precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic stability of human embryonic stem cells: A first-step toward the development of potential hESC-based systems for modeling childhood leukemia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hematopoietic development from human embryonic stem cell lines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality embryos

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A ROCK inhibitor permits survival of dissociated human embryonic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sequential analysis of CD34+ and CD34- cell subsets in peripheral blood and leukapheresis products from breast cancer patients mobilized with SCF plus G-CSF and cyclophosphamide

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of Rho-associated kinase (ROCK) inhibitor Y-27632 on the post-thaw viability of cryopreserved human bone marrow-derived mesenchymal stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term follow-up of leukaemia patients after related cryopreserved allogeneic bone marrow transplantation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of viability during freeze-thaw of intact and adherent human embryonic stem cells with conventional slow-cooling protocols is predominantly due to apoptosis rather than cellular necrosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-bone marrow transplantation facilitates pauci-clonal human hematopoietic repopulation of NOD/SCID/beta2m(-/-) mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Novel cryopreservation method for dissociated human embryonic stem cells in the presence of a ROCK inhibitor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The ROCK inhibitor Y-27632 enhances the survival rate of human embryonic stem cells following cryopreservation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human embryonic stem cells: caught between a ROCK inhibitor and a hard place.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved post-thaw recovery of peripheral blood stem/progenitor cells using a novel intracellular-like cryopreservation solution

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of ROCK inhibitor Y-27632 on normal and variant human embryonic stem cells (hESCs) in vitro: its benefits in hESC expansion

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ROCK inhibition enhances the recovery and growth of cryopreserved human embryonic stem cells and human induced pluripotent stem cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of the different CD34+ and CD34- cell subsets infused on clinical outcome after non-myeloablative allogeneic peripheral blood transplantation from human leucocyte antigen-identical sibling donors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Small GTP-binding proteins and the regulation of the actin cytoskeleton

1 reference

https://pubmed.ncbi.nlm.nih.gov/20180051

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12015-010-9118-5

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

1 reference

Europe PubMed Central

2 June 2018

http://europepmc.org/abstract/MED/20180051

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