A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response. (Q54487776)

30 May 2018

title

A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response. (English)

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30 May 2018

author

Thomas Reinert

6

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30 May 2018

Lars Dyrskjøt

13

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30 May 2018

author name string

T Schepeler

1

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30 May 2018

P Lamy

2

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30 May 2018

V Hvidberg

3

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30 May 2018

J R Laurberg

4

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30 May 2018

N Fristrup

5

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J Bartkova

7

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30 May 2018

L Tropia

8

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30 May 2018

J Bartek

9

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30 May 2018

T D Halazonetis

10

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30 May 2018

C-C Pan

11

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30 May 2018

M Borre

12

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T F Orntoft

14

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30 May 2018

language of work or name

English

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publication date

27 August 2012

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30 May 2018

published in

Oncogene

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30 May 2018

volume

32

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30 May 2018

issue

31

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30 May 2018

page(s)

3577-3586

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30 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2012.381

exact match

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cites work

Global cancer statistics

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Urothelial tumorigenesis: a tale of divergent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Combined gene expression and genomic profiling define two intrinsic molecular subtypes of urothelial carcinoma and gene signatures for molecular grading and outcome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Bladder cancer stage and outcome by array-based comparative genomic hybridization

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Consistent genomic alterations in carcinoma in situ of the urinary bladder confirm the presence of two major pathways in bladder cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Chromosomal imbalance in the progression of high-risk non-muscle invasive bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Genomic instability--an evolving hallmark of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

An oncogene-induced DNA damage model for cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

The DNA-damage response in human biology and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

The DNA Damage Response: Making It Safe to Play with Knives

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

The many facets of the Tim-Tipin protein families' roles in chromosome biology.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Amplification and overexpression of the ID4 gene at 6p22.3 in bladder cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

GLO1-A novel amplified gene in human cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Alteration of the LRP1B gene region is associated with high grade of urothelial cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Studies of genomic copy number changes in human cancers reveal signatures of DNA replication stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Molecular profiling of common fragile sites in human fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

The consequences of uniparental disomy and copy number neutral loss-of-heterozygosity during human development and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Signatures of mutation and selection in the cancer genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Oligoclonality in bladder cancer: the implication for molecular therapies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

DNA damage response and inflammatory signaling limit the MLL-ENL-induced leukemogenesis in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Cell-cycle checkpoints and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

TP53 mutations in human cancers: origins, consequences, and clinical use

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Predicting recurrence and progression in individual patients with stage Ta T1 bladder cancer using EORTC risk tables: a combined analysis of 2596 patients from seven EORTC trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Aneuploidy acts both oncogenically and as a tumor suppressor

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

The DNA damage response and cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Uniparental disomy in cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Hyperactivation of Ha-ras oncogene, but not Ink4a/Arf deficiency, triggers bladder tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Clonality of multifocal urothelial carcinomas: 10 years of molecular genetic studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Timeless links replication termination to mitotic kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Mammalian TIMELESS is required for ATM-dependent CHK2 activation and G2/M checkpoint control

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Coupling of human circadian and cell cycles by the timeless protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

BRCA1, PARP, and 53BP1: conditional synthetic lethality and synthetic viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

FGFR3, HRAS, KRAS, NRAS and PIK3CA mutations in bladder cancer and their potential as biomarkers for surveillance and therapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Clusterin expression can be modulated by changes in TCF1-mediated Wnt signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Integrative genomics viewer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Comprehensive Genome Methylation Analysis in Bladder Cancer: Identification and Validation of Novel Methylated Genes and Application of These as Urinary Tumor Markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

Genetic and epigenetic associations of circadian gene TIMELESS and breast cancer risk

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2012.381

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.381

1 reference

30 May 2018

PubMed ID

22926521

1 reference

30 May 2018