Monitoring of WT1 expression in PB and CD34(+) donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with reduced-intensity conditioning. (Q54398542)

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English	Monitoring of WT1 expression in PB and CD34(+) donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with reduced-intensity conditioning.	scientific article

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scholarly article

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/21135860

Monitoring of WT1 expression in PB and CD34(+) donor chimerism of BM predicts early relapse in AML and MDS patients after hematopoietic cell transplantation with reduced-intensity conditioning. (English)

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/21135860

Ralph Burkhardt

3

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http://europepmc.org/abstract/MED/21135860

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object named as

J Thiery

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author name string

T Lange

1

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29 May 2018

http://europepmc.org/abstract/MED/21135860

M Hubmann

2

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29 May 2018

http://europepmc.org/abstract/MED/21135860

G-N Franke

4

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29 May 2018

http://europepmc.org/abstract/MED/21135860

M Cross

5

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http://europepmc.org/abstract/MED/21135860

M Scholz

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http://europepmc.org/abstract/MED/21135860

S Leiblein

7

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http://europepmc.org/abstract/MED/21135860

H K Al-Ali

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http://europepmc.org/abstract/MED/21135860

J Edelmann

9

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http://europepmc.org/abstract/MED/21135860

D Niederwieser

11

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http://europepmc.org/abstract/MED/21135860

publication date

7 December 2010

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http://europepmc.org/abstract/MED/21135860

3

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http://europepmc.org/abstract/MED/21135860

498-505

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http://europepmc.org/abstract/MED/21135860

https://scigraph.springernature.com/pub.10.1038/leu.2010.283

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Can reduced-intensity allogeneic transplantation cure older adults with AML?

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Reduced intensity conditioning (RIC) haematopoietic cell transplants in elderly patients with AML.

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Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free survival in patients with high-risk acute myeloid leukemia and myelodysplasia

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Fluorescence in situ hybridization: uses and limitations

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Diagnostic chimerism analysis after allogeneic stem cell transplantation: new methods and markers.

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WT1 as a universal marker for minimal residual disease detection and quantification in myeloid leukemias and in myelodysplastic syndrome.

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Wilms' tumour gene 1 (WT1) in human neoplasia.

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WT1 gene expression: an excellent tool for monitoring minimal residual disease in 70% of acute myeloid leukaemia patients - results from a single-centre study

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Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: a European LeukemiaNet study.

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Prognostic impact of RT-PCR-based quantification of WT1 gene expression during MRD monitoring of acute myeloid leukemia

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High WT1 expression after induction therapy predicts high risk of relapse and death in pediatric acute myeloid leukemia.

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Early prediction of treatment outcome in acute myeloid leukemia by measurement of WT1 transcript levels in peripheral blood samples collected after chemotherapy

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WT1 gene transcript assay for relapse in acute leukemia after transplantation

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Quantitative assessment of WT1 gene expression after allogeneic stem cell transplantation is a useful tool for monitoring minimal residual disease in acute myeloid leukemia.

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Low-dose total body irradiation (TBI) and fludarabine followed by hematopoietic cell transplantation (HCT) from HLA-matched or mismatched unrelated donors and postgrafting immunosuppression with cyclosporine and mycophenolate mofetil (MMF) can induc

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Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority

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Residual Disease in Chronic Myeloid Leukemia after Induction of Molecular Remission

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R: A Language for Data Analysis and Graphics

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Monitoring of donor chimerism in sorted CD34+ peripheral blood cells allows the sensitive detection of imminent relapse after allogeneic stem cell transplantation

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Use of dual-color interphase FISH for the detection of inv(16) in acute myeloid leukemia at diagnosis, relapse and during follow-up: a study of 23 patients

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Prognostic impact of WT1 mutations in cytogenetically normal acute myeloid leukemia: a study of the German-Austrian AML Study Group

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Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia.

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Nonmyeloablative allogeneic hematopoietic cell transplantation in patients with acute myeloid leukemia

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Relapse or progression after hematopoietic cell transplantation using nonmyeloablative conditioning: effect of interventions on outcome

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Compassionate use of sorafenib in FLT3-ITD-positive acute myeloid leukemia: sustained regression before and after allogeneic stem cell transplantation

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Wilms' tumor 1 mutation accumulated during therapy in acute myeloid leukemia: biological and clinical implications

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Long-term remissions in patients with myelodysplastic syndrome and secondary acute myelogenous leukemia undergoing allogeneic transplantation following a reduced intensity conditioning regimen of 550 cGy total body irradiation and cyclophosphamide

1 reference

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Elevated levels of WT1 transcripts in bone marrow harvests are associated with a high relapse risk in patients autografted for acute myeloid leukaemia

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7 January 2021

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The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia

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Evaluation of complete disease remission in acute myeloid leukemia: a prospective study based on cytomorphology, interphase fluorescence in situ hybridization, and immunophenotyping during follow-up in patients with acute myeloid leukemia

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Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative allogeneic hematopoietic cell transplantation

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Identifiers

10.1038/LEU.2010.283

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/21135860

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/21135860

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