Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications. (Q54389429)

From Wikidata

Jump to navigation Jump to search

scientific article

Language	Label	Description	Also known as
English	Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.	scientific article

Statements

scholarly article

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications. (English)

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

1 reference

based on heuristic

inferred from title

author name string

Vivian Kosmidou

1

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Eftychia Oikonomou

2

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Margarita Vlassi

3

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Spyros Avlonitis

4

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Anastasia Katseli

5

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Iraklis Tsipras

6

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Despina Mourtzoukou

7

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Georgios Kontogeorgos

8

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Georgios Zografos

9

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Alexander Pintzas

10

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

publication date

15 January 2014

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

35

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

329-340

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

3

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

Clinicopathological analysis of colorectal cancers with PIK3CA mutations in Middle Eastern population

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Combined mutational analysis of KRAS, NRAS and BRAF genes in Indian patients with colorectal carcinoma.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Mutations in the RAS-MAPK, PI(3)K (phosphatidylinositol-3-OH kinase) signaling network correlate with poor survival in a population-based series of colon cancers.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

PIK3CA cancer mutations display gender and tissue specificity patterns.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Detection of KRAS mutations in colorectal carcinoma patients with an integrated PCR/sequencing and real-time PCR approach.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Computational analysis of KRAS mutations: implications for different effects on the KRAS p.G12D and p.G13D mutations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Mutations of the BRAF gene in human cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

EGFR and colon cancer: a clinical view.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

KRAS, BRAF, PIK3CA, and PTEN mutations: implications for targeted therapies in metastatic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Recurrent KRAS codon 146 mutations in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The prognostic role of KRAS, BRAF, PIK3CA and PTEN in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Targeting PI3K signalling in cancer: opportunities, challenges and limitations

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The BRAF V600E mutation is an independent prognostic factor for survival in stage II and stage III colon cancer patients

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

A genetic model for colorectal tumorigenesis

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Molecular circuits of solid tumors: prognostic and predictive tools for bedside use.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Phosphatidylinositol 3-kinase mutations identified in human cancer are oncogenic

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Molecular strategies targeting the host component of cancer to enhance tumor response to radiation therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The frequency of KRAS mutation detection in human colon carcinoma is influenced by the sensitivity of assay methodology: a comparison between direct sequencing and real-time PCR.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Tumour heterogeneity and drug resistance: personalising cancer medicine through functional genomics

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Aspirin use, tumor PIK3CA mutation, and colorectal-cancer survival

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

KRAS codon 61, 146 and BRAF mutations predict resistance to cetuximab plus irinotecan in KRAS codon 12 and 13 wild-type metastatic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The use of COLD-PCR and high-resolution melting analysis improves the limit of detection of KRAS and BRAF mutations in colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

KRAS p.G13D mutations are associated with sensitivity to anti-EGFR antibody treatment in colorectal cancer cell lines

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Increased detection sensitivity for KRAS mutations enhances the prediction of anti-EGFR monoclonal antibody resistance in metastatic colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Aspirin use and risk of colorectal cancer according to BRAF mutation status

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Sensitive sequencing method for KRAS mutation detection by Pyrosequencing

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

PIK3CA mutation is associated with poor prognosis among patients with curatively resected colon cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Many different tumor types have polyclonal tumor origin: evidence and implications.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Novel mutant-enriched sequencing identified high frequency of PIK3CA mutations in pharyngeal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Intra-tumoral heterogeneity of KRAS and BRAF mutation status in patients with advanced colorectal cancer (aCRC) and cost-effectiveness of multiple sample testing.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The phosphoinositide 3-kinase signalling pathway as a therapeutic target in squamous cell carcinoma of the head and neck.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

High frequency of mutations of the PIK3CA gene in human cancers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The epidermal growth factor receptor pathway: a model for targeted therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Absence of tyrosine kinase mutations in Japanese colorectal cancer patients.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

PIK3CA is implicated as an oncogene in ovarian cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Prognostic and predictive value of common mutations for treatment response and survival in patients with metastatic colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Intratumor heterogeneity: evolution through space and time

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Comparison of Sanger sequencing, pyrosequencing, and melting curve analysis for the detection of KRAS mutations: diagnostic and clinical implications

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

The prevalence of PIK3CA mutations in gastric and colon cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Frequency and spectrum of K-RAS codons 12 and 13 mutations in colorectal adenocarcinomas from Taiwan.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Pyrosequencing cut-off value identifying BRAFV600E mutation in fine needle aspiration samples of thyroid nodules.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Stem cells and their implications for colorectal cancer.

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Patterns of K-ras mutation in colorectal carcinomas from Iran and Italy (a Gruppo Oncologico dell'Italia Meridionale study): influence of microsatellite instability status and country of origin

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Clonality Assessment and Clonal Ordering of Individual Neoplastic Crypts Shows Polyclonality of Colorectal Adenomas

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

21 January 2018

Prevalence and heterogeneity of KRAS, BRAF, and PIK3CA mutations in primary colorectal adenocarcinomas and their corresponding metastases

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Mutation analysis of p53, K-ras, and BRAF genes in colorectal cancer progression

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

PIK3CA mutation is predictive of poor survival in patients with colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Patient with colorectal cancer with heterogeneous KRAS molecular status responding to cetuximab-based chemotherapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Patterns ofPIK3CA alterations in familial colorectal and endometrial carcinoma

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Heterogeneous distribution of K-ras mutations in primary colon carcinomas: implications for EGFR-directed therapy

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Oncogenic mutations of PIK3CA in human cancers

1 reference

https://api.crossref.org/works/10.1002%2FHUMU.22496

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/HUMU.22496

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

1 reference

Europe PubMed Central

29 May 2018

http://europepmc.org/abstract/MED/24352906

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q54389429&oldid=1795916106"