ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway. (Q54313198)

27 May 2018

title

ERβ decreases breast cancer cell survival by regulating the IRE1/XBP-1 pathway. (English)

1 reference

27 May 2018

author

Robert Clarke

4

1 reference

27 May 2018

author name string

G Rajapaksa

1

1 reference

27 May 2018

F Nikolos

2

1 reference

27 May 2018

I Bado

3

1 reference

27 May 2018

J-Å Gustafsson

5

1 reference

27 May 2018

C Thomas

6

1 reference

27 May 2018

language of work or name

English

0 references

publication date

27 October 2014

1 reference

27 May 2018

published in

Oncogene

1 reference

27 May 2018

volume

34

1 reference

27 May 2018

issue

31

1 reference

27 May 2018

page(s)

4130-4141

1 reference

27 May 2018

https://scigraph.springernature.com/pub.10.1038/onc.2014.343

exact match

0 references

cites work

Comprehensive molecular portraits of human breast tumours

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

21 January 2018

Cancer statistics, 2014

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

The different roles of ER subtypes in cancer biology and therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Targeting XBP-1 as a novel anti-cancer strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

The role of the unfolded protein response in tumour development: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

The unfolded protein response: a stress signaling pathway critical for health and disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Endoplasmic reticulum stress: cell life and death decisions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

GRP78/BiP inhibits endoplasmic reticulum BIK and protects human breast cancer cells against estrogen starvation-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Glucose-regulated protein 78 controls cross-talk between apoptosis and autophagy to determine antiestrogen responsiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

GRP78 as potential predictor for breast cancer response to adjuvant taxane therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Human X-box binding protein-1 confers both estrogen independence and antiestrogen resistance in breast cancer cell lines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Expression and splicing of the unfolded protein response gene XBP-1 are significantly associated with clinical outcome of endocrine-treated breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Ligand-independent activation of estrogen receptor alpha by XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

ERbeta1 represses basal breast cancer epithelial to mesenchymal transition by destabilizing EGFR

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Clinical importance of estrogen receptor-beta evaluation in breast cancer patients treated with adjuvant tamoxifen therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Differential dependency network analysis to identify condition-specific topological changes in biological networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

PES1 promotes breast cancer by differentially regulating ERα and ERβ.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Bortezomib for the treatment of mantle cell lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Staurosporine is a potent inhibitor of p34cdc2 and p34cdc2-like kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Estrogen receptor beta decreases survival of p53-defective cancer cells after DNA damage by impairing G₂/M checkpoint signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Tyrosine-phosphorylated caveolin-1 (Tyr-14) increases sensitivity to paclitaxel by inhibiting BCL2 and BCLxL proteins via c-Jun N-terminal kinase (JNK).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Synoviolin promotes IRE1 ubiquitination and degradation in synovial fibroblasts from mice with collagen-induced arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Heat shock protein 90 modulates the unfolded protein response by stabilizing IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Nuclear and cytoplasmic expression of ERbeta1, ERbeta2, and ERbeta5 identifies distinct prognostic outcome for breast cancer patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Tumor repressive functions of estrogen receptor beta in SW480 colon cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

ERβ regulates NSCLC phenotypes by controlling oncogenic RAS signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Bortezomib (VELCADE) in metastatic breast cancer: pharmacodynamics, biological effects, and prediction of clinical benefits

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

A proteasome inhibitor, bortezomib, inhibits breast cancer growth and reduces osteolysis by downregulating metastatic genes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated by estrogen receptor-beta/NFkappaB crosstalk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

ERdj5 sensitizes neuroblastoma cells to endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

A time-dependent phase shift in the mammalian unfolded protein response

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2014.343

Endoplasmic reticulum stress, the unfolded protein response, autophagy, and the integrated regulation of breast cancer cell fate.

31 March 2020

1 reference

12 December 2020

Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer

1 reference

12 December 2020

Estrogen regulation of X-box binding protein-1 and its role in estrogen induced growth of breast and endometrial cancer cells

1 reference

12 December 2020

Responses to retinoic acid of tamoxifen-sensitive and -resistant sublines of human breast cancer cell line MCF-7

1 reference

12 December 2020

Relation of in vitro properties to tumorigenicity for a series of sublines of the human breast cancer cell line MCF-7

1 reference

12 December 2020

Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780).

1 reference

12 December 2020

Identifiers

DOI

10.1038/ONC.2014.343

1 reference

27 May 2018

PubMed ID

25347741

1 reference

27 May 2018