Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation. (Q54307814)

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23 February 2020

title

Constitutive phosphorylation of the active Notch1 intracellular domain in chronic lymphocytic leukemia cells with NOTCH1 mutation (English)

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23 February 2020

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chronic lymphocytic leukemia

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1

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23 February 2020

Paolo Sportoletti

5

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23 February 2020

Stefano Baldoni

6

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23 February 2020

Beatrice Del Papa

7

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23 February 2020

Emanuela Rosati

10

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23 February 2020

author name string

R Sabatini

2

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F Falzetti

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23 February 2020

M Di Ianni

4

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I Screpanti

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P Marconi

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publication date

26 November 2014

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23 February 2020

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23 February 2020

volume

29

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issue

4

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page(s)

994-998

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https://scigraph.springernature.com/pub.10.1038/leu.2014.329

23 February 2020

exact match

0 references

cites work

A revised NOTCH1 mutation frequency still impacts survival while the allele burden predicts early progression in chronic lymphocytic leukemia.

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Functional impact of NOTCH1 mutations in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

The molecular basis of notch signaling regulation: a complex simplicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Hierarchical phosphorylation within the ankyrin repeat domain defines a phosphoregulatory loop that regulates Notch transcriptional activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Down-regulation of Notch-dependent transcription by Akt in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Glycogen synthase kinase 3-β phosphorylates novel S/T-P-S/T domains in Notch1 intracellular domain and induces its nuclear localization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Notch(ic)-ER chimeras display hormone-dependent transformation, nuclear accumulation, phosphorylation and CBF1 activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Inhibition of glycogen synthase kinase-3 activity leads to epigenetic silencing of nuclear factor kappaB target genes and induction of apoptosis in chronic lymphocytic leukemia B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Reconstitution of PTEN activity by CK2 inhibitors and interference with the PI3-K/Akt cascade counteract the antiapoptotic effect of human stromal cells in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Emerging role of kinase-targeted strategies in chronic lymphocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

NOTCH1 PEST domain mutation is an adverse prognostic factor in B-CLL

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25425197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25425197

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Muscarinic agonists induce phosphorylation-independent activation of the NHE-1 isoform of the Na+/H+ antiporter in salivary acinar cells

1 reference

https://api.crossref.org/works/10.1038%2FLEU.2014.329

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/LEU.2014.329

1 reference

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23 February 2020

1 reference