Alpha-1-antitrypsin deficiency: from genoma to liver disease. PiZ mouse as model for the development of liver pathology in human. (Q54222676)

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title

Alpha-1-antitrypsin deficiency: from genoma to liver disease. PiZ mouse as model for the development of liver pathology in human (English)

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alpha-1-antitrypsin deficiency

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main subject

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1

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Filippo Maria Santorelli

5

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author name string

Francesco Callea

2

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Marta Stefanelli

3

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Riccardo Mariani

4

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Paola Francalanci

6

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publication date

11 March 2014

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volume

35

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issue

1

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page(s)

198-206

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Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

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cites work

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Z α-1 antitrypsin deficiency and the endoplasmic reticulum stress response

21 January 2018

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Alpha 1-antitrypsin deficiency, emphysema, and liver disease. Genetic basis and strategies for therapy

21 January 2018

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Pathogenesis of chronic liver injury and hepatocellular carcinoma in alpha-1-antitrypsin deficiency

21 January 2018

1 reference

Tissue specific expression of the human alpha-1-antitrypsin gene in transgenic mice

21 January 2018

1 reference

Accumulation of PiZ alpha 1-antitrypsin causes liver damage in transgenic mice

21 January 2018

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Analyses of hepatocellular proliferation in a mouse model of alpha-1-antitrypsin deficiency

21 January 2018

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Quantitative isolation of alphalAT mutant Z protein polymers from human and mouse livers and the effect of heat

21 January 2018

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Alpha-1-antitrypsin mutant Z protein content in individual hepatocytes correlates with cell death in a mouse model.

21 January 2018

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Alpha-1-antitrypsin deficiency: importance of proteasomal and autophagic degradative pathways in disposal of liver disease-associated protein aggregates

21 January 2018

1 reference

Proliferative and nonproliferative lesions of the rat and mouse hepatobiliary system

21 January 2018

1 reference

Plasminogen activator inhibitor-1 deficient mice are protected from angiotensin II-induced fibrosis

21 January 2018

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Differentiation of mouse embryonic stem cells into hepatocytes induced by a combination of cytokines and sodium butyrate

21 January 2018

1 reference

Is heterozygous alpha-1-antitrypsin deficiency type PIZ a risk factor for primary liver carcinoma?

21 January 2018

1 reference

Self-induced correction of the genetic defect in tyrosinemia type I

21 January 2018

1 reference

Alpha-1-antitrypsin deficiency: a new paradigm for hepatocellular carcinoma in genetic liver disease

21 January 2018

1 reference

Characteristics of hepatocellular carcinoma in a murine model of alpha-1-antitrypsin deficiency

21 January 2018

1 reference

Stem and progenitor cells for liver repopulation: can we standardise the process from bench to bedside?

21 January 2018

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Molecular basis, clinical consequences and diagnosis of alpha-1 antitrypsin deficiency

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/LIV.12504

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