Transplastomic expression of a modified human papillomavirus L1 protein leading to the assembly of capsomeres in tobacco: a step towards cost-effective second-generation vaccines. (Q54080674)

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English	Transplastomic expression of a modified human papillomavirus L1 protein leading to the assembly of capsomeres in tobacco: a step towards cost-effective second-generation vaccines.	scientific article

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5 February 2020

Transplastomic expression of a modified human papillomavirus L1 protein leading to the assembly of capsomeres in tobacco: a step towards cost-effective second-generation vaccines (English)

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5 February 2020

Mohammad Tahir Waheed

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5 February 2020

Syed Waqas Hassan

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5 February 2020

Hans-Peter Kaul

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5 February 2020

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Nadja Thönes

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5 February 2020

Martin Müller

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5 February 2020

N Mona Razavi

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5 February 2020

Elke Lössl

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5 February 2020

Andreas G Lössl

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5 February 2020

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19 June 2010

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5 February 2020

Transgenic Research

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5 February 2020

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5 February 2020

2

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5 February 2020

271-282

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5 February 2020

https://scigraph.springernature.com/pub.10.1007/s11248-010-9415-4

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Structures of bovine and human papillomaviruses. Analysis by cryoelectron microscopy and three-dimensional image reconstruction

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Production of human papillomavirus type 16 virus-like particles in transgenic plants

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Plastid biotechnology: prospects for herbicide and insect resistance, metabolic engineering and molecular farming

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Cytoplasmic male sterility: a window to the world of plant mitochondrial-nuclear interactions

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Chloroplast-derived vaccine antigens and biopharmaceuticals: expression, folding, assembly and functionality

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Structure of small virus-like particles assembled from the L1 protein of human papillomavirus 16

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21 January 2018

Papillomavirus capsid protein expression in Escherichia coli: purification and assembly of HPV11 and HPV16 L1.

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21 January 2018

Medical molecular farming: production of antibodies, biopharmaceuticals and edible vaccines in plants

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21 January 2018

Plant-made vaccine antigens and biopharmaceuticals

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21 January 2018

Human papillomavirus L1 protein expressed in tobacco chloroplasts self-assembles into virus-like particles that are highly immunogenic

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21 January 2018

Induction of type-specific neutralizing antibodies by capsomeres of human papillomavirus type 33.

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21 January 2018

Nutrient requirements of suspension cultures of soybean root cells

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The two RNA polymerases encoded by the nuclear and the plastid compartments transcribe distinct groups of genes in tobacco plastids

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21 January 2018

Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial

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21 January 2018

Mutational analysis of human papillomavirus type 16 major capsid protein L1: the cysteines affecting the intermolecular bonding and structure of L1-capsids

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21 January 2018

A controlled trial of a human papillomavirus type 16 vaccine

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21 January 2018

Somaclonal variation - a novel source of variability from cell cultures for plant improvement

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21 January 2018

Translational fusion of chloroplast-expressed human papillomavirus type 16 L1 capsid protein enhances antigen accumulation in transplastomic tobacco.

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21 January 2018

Expression of human papillomavirus type 16 L1 protein in transgenic tobacco plants.

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21 January 2018

Inducible trans-activation of plastid transgenes: expression of the R. eutropha phb operon in transplastomic tobacco.

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21 January 2018

Molecular farming for new drugs and vaccines. Current perspectives on the production of pharmaceuticals in transgenic plants

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21 January 2018

Optimization of human papillomavirus type 16 (HPV-16) L1 expression in plants: comparison of the suitability of different HPV-16 L1 gene variants and different cell-compartment localization.

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21 January 2018

Engineering the plastid genome of higher plants

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21 January 2018

A long way: history of the prophylactic papillomavirus vaccine

1 reference

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21 January 2018

A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures

1 reference

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21 January 2018

Rapid isolation of high molecular weight plant DNA

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21 January 2018

Exhaustion of the chloroplast protein synthesis capacity by massive expression of a highly stable protein antibiotic.

1 reference

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21 January 2018

Human papillomavirus type 16 L1 capsomeres induce L1-specific cytotoxic T lymphocytes and tumor regression in C57BL/6 mice

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21 January 2018

The molecular biology of cytoplasmically inherited male sterility and prospects for its engineering

1 reference

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21 January 2018

Determining the transgene containment level provided by chloroplast transformation

1 reference

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21 January 2018

Engineering cytoplasmic male sterility via the chloroplast genome by expression of {beta}-ketothiolase.

1 reference

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21 January 2018

Organization of the major and minor capsid proteins in human papillomavirus type 33 virus-like particles

1 reference

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21 January 2018

Refining HPV 16 L1 purification from E. coli: reducing endotoxin contaminations and their impact on immunogenicity

1 reference

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21 January 2018

Analysis of modified human papillomavirus type 16 L1 capsomeres: the ability to assemble into larger particles correlates with higher immunogenicity

1 reference

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21 January 2018

Human papillomavirus type distribution in invasive cervical cancer and high-grade cervical lesions: a meta-analysis update.

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21 January 2018

Immunobiology of human papillomavirus infection and vaccination - implications for second generation vaccines.

1 reference

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21 January 2018

Use of T7 RNA polymerase to direct expression of cloned genes

1 reference

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21 January 2018

High-frequency plastid transformation in tobacco by selection for a chimeric aadA gene

1 reference

https://api.crossref.org/works/10.1007%2FS11248-010-9415-4

21 January 2018

Stable transformation of plastids in higher plants

1 reference

https://api.crossref.org/works/10.1007%2FS11248-010-9415-4

21 January 2018

A direct comparison of human papillomavirus type 16 L1 particles reveals a lower immunogenicity of capsomeres than viruslike particles with respect to the induced antibody response

1 reference

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21 January 2018

High sustained efficacy of a prophylactic quadrivalent human papillomavirus types 6/11/16/18 L1 virus-like particle vaccine through 5 years of follow-up

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21 January 2018

Plastid-expressed 5-enolpyruvylshikimate-3-phosphate synthase genes provide high level glyphosate tolerance in tobacco

1 reference

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21 January 2018

Immunization with a pentameric L1 fusion protein protects against papillomavirus infection

1 reference

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21 January 2018

Human papillomavirus type 11 recombinant L1 capsomeres induce virus-neutralizing antibodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

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Intranasal immunization with human papillomavirus type 16 capsomeres in the presence of non-toxic cholera toxin-based adjuvants elicits increased vaginal immunoglobulin levels

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Technical Advance: Stable chloroplast transformation in potato: use of green fluorescent protein as a plastid marker

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the human papillomavirus type 11 L1 capsid protein in Escherichia coli: characterization of protein domains involved in DNA binding and capsid assembly

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative disassembly and reassembly of human papillomavirus type 11 viruslike particles in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The complete nucleotide sequence of the tobacco chloroplast genome: its gene organization and expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plant-based production of biopharmaceuticals

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of Human papillomavirus type 16 major capsid protein in transgenic Nicotiana tabacum cv. Xanthi

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chapter 2: The burden of HPV-related cancers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral immunization with different assembly forms of the HPV 16 major capsid protein L1 induces neutralizing antibodies and cytotoxic T-lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Papillomavirus assembly requires trimerization of the major capsid protein by disulfides between two highly conserved cysteines

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

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inferred from PubMed ID database lookup

Polyester synthesis in transplastomic tobacco (Nicotiana tabacum L.): significant contents of polyhydroxybutyrate are associated with growth reduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20563641

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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