Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes. (Q54067844)

24 May 2018

title

Role of NF-kappaB in the apoptotic-resistant phenotype of keratinocytes. (English)

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24 May 2018

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6

Nickoloff BJ

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24 May 2018

author name string

Qin JZ

1

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24 May 2018

Chaturvedi V

2

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24 May 2018

Denning MF

3

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24 May 2018

Choubey D

4

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24 May 2018

Diaz MO

5

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language of work or name

English

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publication date

1 December 1999

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24 May 2018

Journal of Biological Chemistry

published in

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volume

274

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issue

53

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24 May 2018

page(s)

37957-37964

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24 May 2018

Alterations in NF-kappaB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-kappaB.

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The IkappaB kinase complex (IKK) contains two kinase subunits, IKKalpha and IKKbeta, necessary for IkappaB phosphorylation and NF-kappaB activation

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IkappaBalpha deficiency results in a sustained NF-kappaB response and severe widespread dermatitis in mice

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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Apoptosis in the pathogenesis and treatment of disease

21 January 2018

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Human keratin-1.bcl-2 transgenic mice aberrantly express keratin 6, exhibit reduced sensitivity to keratinocyte cell death induction, and are susceptible to skin tumor formation.

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.274.53.37957

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24 May 2018

PubMed ID

10608863

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24 May 2018