Does a central MHC gene in linkage disequilibrium with HLA-DRB1*0401 affect susceptibility to type 1 diabetes? (Q53859446)

21 May 2018

title

Does a central MHC gene in linkage disequilibrium with HLA-DRB1*0401 affect susceptibility to type 1 diabetes? (English)

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21 May 2018

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linkage disequilibrium

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Windsor L

1

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21 May 2018

Puschendorf M

2

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Allcock R

3

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Scott A

4

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Sayer D

5

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21 May 2018

Kucharzak R

6

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Gut I

7

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McCann V

8

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Davis E

9

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Witt C

10

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Christiansen F

11

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Price P

12

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publication date

1 June 2005

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21 May 2018

published in

Genes and Immunity

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21 May 2018

volume

6

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21 May 2018

issue

4

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page(s)

298-304

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https://scigraph.springernature.com/pub.10.1038/sj.gene.6364210

exact match

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cites work

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HLA-encoded genetic predisposition in IDDM: DR4 subtypes may be associated with different degrees of protection

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HLA class II alleles and susceptibility and resistance to insulin dependent diabetes mellitus in Mexican-American families

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Localization of central MHC genes influencing type I diabetes

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Haplotypic single nucleotide polymorphisms in the central MHC gene IKBL, a potential regulator of NF-kappaB function.

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High-Density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging

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Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis

21 January 2018

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Structural studies of allelic diversity of the MHC class I homolog MIC-B, a stress-inducible ligand for the activating immunoreceptor NKG2D

21 January 2018

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The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production

21 January 2018

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Premature telomeric loss in rheumatoid arthritis is genetically determined and involves both myeloid and lymphoid cell lineages.

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T-cell senescence: a culprit of immune abnormalities in chronic inflammation and persistent infection

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HLA-DRB1 DNA sequencing based typing: an approach suitable for high throughput typing including unrelated bone marrow registry donors

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A novel procedure for efficient genotyping of single nucleotide polymorphisms

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Contribution of DRB1*04 Variants to Predisposition to or Protection from Insulin Dependent Diabetes Mellitus is Independent of DQ

21 January 2018

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7 January 2021

The distribution of DR4 haplotypes in Sardinia suggests a primary association of type I diabetes with DRB1 and DQB1 loci

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7 January 2021

Conditional linkage disequilibrium analysis of a complex disease superlocus, IDDM1 in the HLA region, reveals the presence of independent modifying gene effects influencing the type 1 diabetes risk encoded by the major HLA-DQB1, -DRB1 disease loci

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7 January 2021

HLA antigens and age at diagnosis of insulin-dependent diabetes mellitus

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7 January 2021

Can MHC class II genes mediate resistance to type 1 diabetes?

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Identification of two different HLA B49 DR4 extended haplotypes in the Sardinian population

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7 January 2021

Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B

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Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA

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Association between the transmembrane region polymorphism of MHC class I chain related Gene-A and type 1 diabetes mellitus in Sweden

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7 January 2021

Comment to: Gambelunghe G., Ghaderi, Cosentino A et al. (2000) association of MHC class I chain-related A (MIC-A) gene polymorphism with type I diabetes. Diabetologia 43: 507-514

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7 January 2021

Identifiers

DOI

10.1038/SJ.GENE.6364210

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21 May 2018

PubMed ID

15858601

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21 May 2018