TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation. (Q53540200)

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English	TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation.	scientific article

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scholarly article

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

TAp63-dependent induction of growth differentiation factor 15 (GDF15) plays a critical role in the regulation of keratinocyte differentiation. (English)

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

author name string

Ichikawa T

1

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

Koda T

3

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

Ozaki T

4

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

Nakagawara A

5

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15 May 2018

http://europepmc.org/abstract/MED/17637746

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publication date

16 July 2007

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

27

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15 May 2018

http://europepmc.org/abstract/MED/17637746

4

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

409-420

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Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

https://scigraph.springernature.com/pub.10.1038/sj.onc.1210658

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Macrophage inhibitory cytokine 1 mediates a p53-dependent protective arrest in S phase in response to starvation for DNA precursors

1 reference

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GDF15, a cardioprotective TGF-beta superfamily protein

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Resveratrol enhances the expression of non-steroidal anti-inflammatory drug-activated gene (NAG-1) by increasing the expression of p53.

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Role of macrophage inhibitory cytokine-1 in tumorigenesis and diagnosis of cancer

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MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily

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Expression of a novel member of the TGF-beta superfamily, growth/differentiation factor-15/macrophage-inhibiting cytokine-1 (GDF-15/MIC-1) in adult rat tissues

1 reference

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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

1 reference

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p53 isoforms can regulate p53 transcriptional activity.

1 reference

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Differential roles of p63 isoforms in epidermal development: selective genetic complementation in p63 null mice

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p63 is upstream of IKK alpha in epidermal development

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p63 and p73 transactivate differentiation gene promoters in human keratinocytes

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PLAB, a novel placental bone morphogenetic protein

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p53 family genes: structural comparison, expression and mutation

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

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Unique domain functions of p63 isotypes that differentially regulate distinct aspects of epidermal homeostasis

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Conflicting roles for p63 in skin development and carcinogenesis

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TAp63alpha induces AP-2gamma as an early event in epidermal morphogenesis.

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p63 is the molecular switch for initiation of an epithelial stratification program

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Prostate derived factor in human prostate cancer cells: gene induction by vitamin D via a p53-dependent mechanism and inhibition of prostate cancer cell growth

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S100A2 gene is a direct transcriptional target of p53 homologues during keratinocyte differentiation.

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p53 mutations in human immortalized epithelial cell lines

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Placental transforming growth factor-beta is a downstream mediator of the growth arrest and apoptotic response of tumor cells to DNA damage and p53 overexpression

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p63 is a p53 homologue required for limb and epidermal morphogenesis

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Calcitriol-induced prostate-derived factor: autocrine control of prostate cancer cell growth.

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Differential recognition of response elements determines target gene specificity for p53 and p63

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A p53-type response element in the GDF15 promoter confers high specificity for p53 activation

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Cloning and characterization of a novel member of the transforming growth factor-beta/bone morphogenetic protein family

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PTGF-beta, a type beta transforming growth factor (TGF-beta) superfamily member, is a p53 target gene that inhibits tumor cell growth via TGF-beta signaling pathway

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Proprotein convertases regulate activity of prostate epithelial cell differentiation markers and are modulated in human prostate cancer cells

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p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

1 reference

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P63 and P73: P53 mimics, menaces and more

1 reference

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p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

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Cyclooxygenase inhibitors regulate the expression of a TGF-beta superfamily member that has proapoptotic and antitumorigenic activities.

1 reference

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7 January 2021

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10.1038/SJ.ONC.1210658

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

1 reference

Europe PubMed Central

15 May 2018

http://europepmc.org/abstract/MED/17637746

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