CCN1 secreted by tonsil-derived mesenchymal stem cells promotes endothelial cell angiogenesis via integrin αv β3 and AMPK. (Q53531156)

15 May 2018

title

CCN1 secreted by tonsil-derived mesenchymal stem cells promotes endothelial cell angiogenesis via integrin αv β3 and AMPK. (English)

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15 May 2018

main subject

mesenchymal stem cell

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Sung-Chul Jung

6

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author name string

Yoon Shin Park

1

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15 May 2018

Soojin Hwang

2

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Yoon Mi Jin

3

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15 May 2018

Yeonsil Yu

4

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15 May 2018

Sung-Ae Jung

5

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15 May 2018

Kyung-Ha Ryu

7

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Han Su Kim

8

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15 May 2018

Inho Jo

9

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15 May 2018

publication date

1 January 2015

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15 May 2018

Journal of Cellular Physiology

published in

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15 May 2018

volume

230

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issue

1

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15 May 2018

page(s)

140-149

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15 May 2018

CYR61, a product of a growth factor-inducible immediate early gene, promotes angiogenesis and tumor growth

cites work

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Differentiation of human embryonic stem cells to a parathyroid-like phenotype

21 January 2018

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Regulation of angiogenesis and endothelial cell function by connective tissue growth factor (CTGF) and cysteine-rich 61 (CYR61).

21 January 2018

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The CCN family: a new stimulus package

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Efficient differentiation of human embryonic stem cells to definitive endoderm

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OstemiR: a novel panel of microRNA biomarkers in osteoblastic and osteocytic differentiation from mesencymal stem cells

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Secretome from mesenchymal stem cells induces angiogenesis via Cyr61

21 January 2018

1 reference

Stimulation of angiogenesis by Cyr61 gene: a new therapeutic candidate

21 January 2018

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Cyr61 mediates hepatocyte growth factor-dependent tumor cell growth, migration, and Akt activation

21 January 2018

1 reference

The angiogenic factor cysteine-rich 61 (CYR61, CCN1) supports vascular smooth muscle cell adhesion and stimulates chemotaxis through integrin alpha(6)beta(1) and cell surface heparan sulfate proteoglycans

21 January 2018

1 reference

The CCN family of proteins: structure-function relationships

21 January 2018

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Far-infrared radiation inhibits proliferation, migration, and angiogenesis of human umbilical vein endothelial cells by suppressing secretory clusterin levels.

21 January 2018

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TNFα-induced apoptosis enabled by CCN1/CYR61: pathways of reactive oxygen species generation and cytochrome c release.

21 January 2018

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Mesenchymal stem cells: cell biology and potential use in therapy.

21 January 2018

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Adhesion of human umbilical vein endothelial cells to the immediate-early gene product Cyr61 is mediated through integrin alphavbeta3.

21 January 2018

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CCN1/CYR61: the very model of a modern matricellular protein.

21 January 2018

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Pro-angiogenic activities of CYR61 (CCN1) mediated through integrins alphavbeta3 and alpha6beta1 in human umbilical vein endothelial cells.

21 January 2018

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Crucial role of activin a in tubulogenesis of endothelial cells induced by vascular endothelial growth factor

21 January 2018

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A novel CYR61-triggered 'CYR61-alphavbeta3 integrin loop' regulates breast cancer cell survival and chemosensitivity through activation of ERK1/ERK2 MAPK signaling pathway.

21 January 2018

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CYR61 (CCN1) is essential for placental development and vascular integrity

21 January 2018

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AMP-activated protein kinase (AMPK) signaling in endothelial cells is essential for angiogenesis in response to hypoxic stress.

21 January 2018

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Expression of cyr61, a growth factor-inducible immediate-early gene

21 January 2018

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Uric acid attenuates nitric oxide production by decreasing the interaction between endothelial nitric oxide synthase and calmodulin in human umbilical vein endothelial cells: a mechanism for uric acid-induced cardiovascular disease development

21 January 2018

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Sonic hedgehog induces angiogenesis via Rho kinase-dependent signaling in endothelial cells.

21 January 2018

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Tonsil-derived mesenchymal stromal cells: evaluation of biologic, immunologic and genetic factors for successful banking.

21 January 2018

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Differential expression of CCN-family members in primary human bone marrow-derived mesenchymal stem cells during osteogenic, chondrogenic and adipogenic differentiation

21 January 2018

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Role of Akt signaling in vascular homeostasis and angiogenesis

21 January 2018

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CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells

21 January 2018

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CYR61 regulates BMP-2-dependent osteoblast differentiation through the {alpha}v{beta}3 integrin/integrin-linked kinase/ERK pathway

21 January 2018

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The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts

21 January 2018

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Mesenchymal stem cells hold promise for regenerative medicine

21 January 2018

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Cyr61, product of a growth factor-inducible immediate-early gene, regulates chondrogenesis in mouse limb bud mesenchymal cells

21 January 2018

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Activation of protein kinase C zeta by peroxynitrite regulates LKB1-dependent AMP-activated protein kinase in cultured endothelial cells.

21 January 2018

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Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease

21 January 2018

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The matrix protein CCN1 (CYR61) promotes proliferation, migration and tube formation of endothelial progenitor cells

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JCP.24690

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15 May 2018

PubMed ID

24909560

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15 May 2018