Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-beta 1 expression. (Q53498796)

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scientific article published in May 1991

Language	Label	Description	Also known as
English	Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-beta 1 expression.	scientific article published in May 1991

Statements

scholarly article

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

Liver tumor promotion: effect of phenobarbital on EGF and protein kinase C signal transduction and transforming growth factor-beta 1 expression. (English)

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

Tumor promotion

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based on heuristic

inferred from title

author name string

R L Jirtle

1

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

S A Meyer

2

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

publication date

1 May 1991

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

Digestive Diseases and Sciences

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

36

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Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

5

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Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

659-668

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Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

https://scigraph.springernature.com/pub.10.1007/bf01297035

0 references

Promotion mechanism of phenobarbital and partial hepatectomy in DENA hepatocarcinogenesis cell kinetics effect

1 reference

https://api.crossref.org/works/10.1007%2FBF01297035

21 January 2018

Protein kinase C phosphorylates topoisomerase II: topoisomerase activation and its possible role in phorbol ester-induced differentiation of HL-60 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Long-term survival of functional hepatocytes from adult rat in the presence of phenobarbital in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Modulation of asialoglycoprotein receptor levels in rat liver by phenobarbital treatment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Modulation of epidermal growth factor receptors in rat hepatocytes by two liver tumor-promoting regimens, a choline-deficient and a phenobarbital diet

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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The effect of L-asparaginase on mitotic activity during N-2-fluorenylacetamide hepatocarcinogenesis: subpopulations of nodular cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Independent mechanisms for tumor promoters phenobarbital and 12-O-tetradecanoylphorbol-13-acetate in reduction of epidermal growth factor binding by rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Influence of the duration and the delay of administration of phenobarbital on its modulating effect on rat hepatocarcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Transcription factor AP-2 mediates induction by two different signal-transduction pathways: protein kinase C and cAMP.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Phenobarbital reduces EGF receptors and the ability of physiological concentrations of calcium to suppress hepatocyte proliferation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Quantitative histochemical and autoradiographic studies of hepatocarcinogenesis in rats fed 2-acetylaminofluorene followed by phenobarbital

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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The stimulation by the tumour promoters 12-O-tetradecanoylphorbol-13-acetate and phenobarbital of the growth of primary neonatal rat hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Facilitated expression of adaptive responses to phenobarbital in putative pre-stages of liver cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Phenobarbital-dependent proliferation of putative initiated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Phenobarbital decreases hepatocyte EGF receptor expression independent of protein kinase C activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Expression of endogenous retrovirus-like sequences and cellular oncogenes during phenobarbital treatment and regeneration in rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Heterologous regulation of the epidermal growth factor receptor by palytoxin, a non-12-O-tetradecanoylphorbol-13-acetate-type tumor promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Transforming growth factor beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Biological effects of epidermal growth factor, with emphasis on the gastrointestinal tract and liver: an update

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Expression of transforming growth factor-beta 1 in specific cells and tissues of adult and neonatal mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Inhibition of DNA synthesis in primary cultures of hepatocytes by orotic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Comparison of 5-bromo-2-deoxyuridine and [3H]thymidine for studies of hepatocellular proliferation in rodents.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Sequential alterations in growth control and cell dynamics of rat hepatocytes in early precancerous steps in hepatocarcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Effects of ethinyl estradiol and tamoxifen on liver DNA turnover and new synthesis and appearance of gamma glutamyl transpeptidase-positive foci in female rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Hormone- and tumor promoter-induced activation or membrane association of protein kinase C in intact cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

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Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Alterations induced by phenobarbital, a liver tumor promoter, in hepatocyte receptors for insulin and glucagon and glycogen metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of tumor-promoting agents 12-O-tetradecanoylphorbol-13-acetate and phenobarbital on DNA synthesis of rat hepatocytes in primary culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell kinetics of hepatocytes during the preneoplastic period of diethylnitrosamine-induced liver carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenobarbital and some other liver tumor promoters stimulate DNA synthesis in cultured rat hepatocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Comparative enhancing effects of phenobarbital, amobarbital, diphenylhydantoin, and dichlorodiphenyltrichloroethane on 2-acetylaminofluorene-induced hepatic tumorigenesis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Differential effects of transforming growth factor-beta on proliferation of normal and malignant rat liver epithelial cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

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Transforming growth factor beta mRNA increases during liver regeneration: a possible paracrine mechanism of growth regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

New classes of tumor promoters: teleocidin, aplysiatoxin, and palytoxin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type beta transforming growth factor reversibly inhibits the early proliferative response to partial hepatectomy in the rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor-beta 1: histochemical localization with antibodies to different epitopes

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhanced proliferation of putative preneoplastic cells in rat liver following treatment with the tumor promoters phenobarbital, hexachlorocyclohexane, steroid compounds, and nafenopin

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hepatic processing of transforming growth factor beta in the rat. Uptake, metabolism, and biliary excretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of the clonability of adult parenchymal hepatocytes with the liver tumor promoter phenobarbital.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transforming growth factor beta inhibits DNA synthesis in hepatocytes isolated from normal and regenerating rat liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two independent growth factor-generated signals regulate c-fos and c-myc mRNA levels in Swiss 3T3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduction and enhancement by phenobarbital of hepatocarcinogenesis induced in the rat by 2-acetylaminofluorene.

1 reference

https://pubmed.ncbi.nlm.nih.gov/2022168

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/BF01297035

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

1 reference

Europe PubMed Central

14 May 2018

http://europepmc.org/abstract/MED/2022168

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