Tumor-infiltrating CD39+γδTregs are novel immunosuppressive T cells in human colorectal cancer. (Q53399267)

13 May 2018

title

Tumor-infiltrating CD39+γδTregs are novel immunosuppressive T cells in human colorectal cancer. (English)

1 reference

13 May 2018

1 reference

Jian Huang

14

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author name string

Guoming Hu

1

1 reference

13 May 2018

Pin Wu

2

1 reference

13 May 2018

Pu Cheng

3

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13 May 2018

Zhigang Zhang

4

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13 May 2018

Zhen Wang

5

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13 May 2018

Xiuyan Yu

6

1 reference

13 May 2018

Xuan Shao

7

1 reference

13 May 2018

Dang Wu

8

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13 May 2018

Jun Ye

9

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13 May 2018

Tao Zhang

10

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13 May 2018

Xiaochen Wang

11

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13 May 2018

Fuming Qiu

12

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13 May 2018

Jun Yan

13

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13 May 2018

publication date

6 January 2017

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13 May 2018

published in

OncoImmunology

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13 May 2018

volume

6

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13 May 2018

issue

2

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13 May 2018

page(s)

e1277305

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13 May 2018

NADH oxidase-dependent CD39 expression by CD8(+) T cells modulates interferon gamma responses via generation of adenosine

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Highly prevalent colorectal cancer-infiltrating LAP⁺ Foxp3⁻ T cells exhibit more potent immunosuppressive activity than Foxp3⁺ regulatory T cells

22 May 2018

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22 May 2018

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22 May 2018

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CD39 is highly involved in mediating the suppression activity of tumor-infiltrating CD8+ T regulatory lymphocytes

22 May 2018

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CD39/ENTPD1 expression by CD4+Foxp3+ regulatory T cells promotes hepatic metastatic tumor growth in mice

22 May 2018

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22 May 2018

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Immunologic and prognostic factors associated with overall survival employing a poxviral-based PSA vaccine in metastatic castrate-resistant prostate cancer

22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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22 May 2018

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A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells.

22 May 2018

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22 May 2018

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Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression

22 May 2018

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22 May 2018

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22 May 2018

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Tumor evasion of the immune system by converting CD4+CD25- T cells into CD4+CD25+ T regulatory cells: role of tumor-derived TGF-beta

22 May 2018

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Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells

22 May 2018

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Enhancement of vaccine-mediated antitumor immunity in cancer patients after depletion of regulatory T cells

22 May 2018

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CD4+CD25+ regulatory T cells inhibit natural killer cell functions in a transforming growth factor-beta-dependent manner

22 May 2018

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Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation

22 May 2018

1 reference

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TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

A commensal bacterial product elicits and modulates migratory capacity of CD39(+) CD4 T regulatory subsets in the suppression of neuroinflammation.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

CD39: a new surface marker of mouse regulatory γδ T cells

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

Adenosine regulates CD8 T-cell priming by inhibition of membrane-proximal T-cell receptor signalling

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

Regulatory T cells in colorectal cancer patients suppress anti-tumor immune activity in a COX-2 dependent manner

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5353931

Tumor-Infiltrating FOXP3+ T Regulatory Cells Show Strong Prognostic Significance in Colorectal Cancer

13 August 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F2162402X.2016.1277305

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1080%2F2162402X.2016.1277305

TGF-β promotes immune suppression by inhibiting Treg cell apoptosis

21 January 2018

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12 December 2020

High frequency of tumor-infiltrating FOXP3(+) regulatory T cells predicts improved survival in mismatch repair-proficient colorectal cancer patients

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12 December 2020

The parallel lives of angiogenesis and immunosuppression: cancer and other tales

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12 December 2020

The extracellular fluid of solid carcinomas contains immunosuppressive concentrations of adenosine

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12 December 2020

A unique subset of CD4+CD25highFoxp3+ T cells secreting interleukin-10 and transforming growth factor-beta1 mediates suppression in the tumor microenvironment

1 reference

12 December 2020

10.1080/2162402X.2016.1277305

Identifiers

DOI

1 reference

13 May 2018

PMCID

5353931

1 reference

13 May 2018

PubMed ID

28344891

1 reference

13 May 2018