In vivo genotoxicity evaluation of dimethylarsinic acid in MutaMouse. (Q53394243)

13 May 2018

title

In vivo genotoxicity evaluation of dimethylarsinic acid in MutaMouse. (English)

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13 May 2018

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Yasuhiro Noda

1

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13 May 2018

Takayoshi Suzuki

2

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13 May 2018

Arihiro Kohara

3

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13 May 2018

Akira Hasegawa

4

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13 May 2018

Toshihisa Yotsuyanagi

5

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13 May 2018

Makoto Hayashi

6

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13 May 2018

Toshio Sofuni

7

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13 May 2018

Kenzo Yamanaka

8

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13 May 2018

Shoji Okada

9

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13 May 2018

language of work or name

English

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publication date

1 January 2002

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13 May 2018

published in

Mutation Research

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13 May 2018

volume

513

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13 May 2018

issue

1-2

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13 May 2018

page(s)

205-212

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13 May 2018

Metabolism of 74As-labeled trivalent and pentavalent inorganic arsenic in mice

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Tissue distribution and retention of 74As-dimethylarsinic acid in mice and rats

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Effects of low dietary intake of methionine, choline or proteins on the biotransformation of arsenite in the rabbit

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DNA strand breaks in mammalian tissues induced by methylarsenics

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Dimethylated arsenics induce DNA strand breaks in lung via the production of active oxygen in mice

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7 January 2021

Preferential increase of heterochromatin in venular endothelium of lung in mice after administration of dimethylarsinic acid, a major metabolite of inorganic arsenics

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7 January 2021

Gene damage induced in human alveolar type II (L-132) cells by exposure to dimethylarsinic acid

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7 January 2021

Crosslink formation between DNA and nuclear proteins by in vivo and in vitro exposure of cells to dimethylarsinic acid

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7 January 2021

Involvement of preferential formation of apurinic/apyrimidinic sites in dimethylarsenic-induced DNA strand breaks and DNA-protein crosslinks in cultured alveolar epithelial cells

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Induction of DNA damage by dimethylarsine, a metabolite of inorganic arsenics, is for the major part likely due to its peroxyl radical

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Exposure to dimethylarsinic acid, a main metabolite of inorganic arsenics, strongly promotes tumorigenesis initiated by 4-nitroquinoline 1-oxide in the lungs of mice.

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Organ variation in the mutagenicity of ethylnitrosourea in Muta mouse: results of the collaborative study on the transgenic mutation assay by JEMS/MMS. The Collaborative Study Group for the Transgenic Mouse Mutation Assay Mammalian Mutagenesis Study

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The micronucleus assay with mouse peripheral blood reticulocytes using acridine orange-coated slides

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Is the genotoxic effect of arsenic mediated by oxygen free radicals?

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7 January 2021

Dimethylarsenic acid induces tetraploids in Chinese hamster cells

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Genetic toxicology of a paradoxical human carcinogen, arsenic: a review

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7 January 2021

10.1016/S1383-5718(01)00313-8

Identifiers

DOI

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13 May 2018

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13 May 2018