Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype. (Q53368680)

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English	Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype.	scientific article

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22 February 2020

Collagen-Derived N-Acetylated Proline-Glycine-Proline in Intervertebral Discs Modulates CXCR1/2 Expression and Activation in Cartilage Endplate Stem Cells to Induce Migration and Differentiation Toward a Pro-Inflammatory Phenotype (English)

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Yang Zhang

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Minghui Yang

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Bo Huang

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Yue Zhou

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1 December 2015

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3558-3568

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10 November 2021

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Differentiation of mesenchymal stem cells towards a nucleus pulposus-like phenotype in vitro: implications for cell-based transplantation therapy

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Characteristics of stem cells derived from the degenerated human intervertebral disc cartilage endplate

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The effects of microenvironment in mesenchymal stem cell-based regeneration of intervertebral disc

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Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.

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Role of cytokines in intervertebral disc degeneration: pain and disc content

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A novel proteolytic cascade generates an extracellular matrix-derived chemoattractant in chronic neutrophilic inflammation

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A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.

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N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD

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Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease.

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The molecular basis of intervertebral disc degeneration

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Magnetic resonance classification of lumbar intervertebral disc degeneration.

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Imaging of degenerative disk disease

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Zonal responsiveness of the human intervertebral disc to bone morphogenetic protein-2.

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Macrophage migration inhibitory factor inhibits the migration of cartilage end plate-derived stem cells by reacting with CD74

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21 January 2018

Identification of N-acetyl Proline-Glycine-Proline (acPGP) in human serum of adults and newborns by liquid chromatography-tandem mass spectrometry

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21 January 2018

Enhancement of intervertebral disc cell senescence by WNT/β-catenin signaling-induced matrix metalloproteinase expression

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21 January 2018

The role of interleukin-1 in the pathogenesis of human intervertebral disc degeneration

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21 January 2018

Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1beta and TNFalpha expression profile.

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Chemokine profile of herniated intervertebral discs infiltrated with monocytes and macrophages

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Expression and relationship of proinflammatory chemokine RANTES/CCL5 and cytokine IL-1β in painful human intervertebral discs

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21 January 2018

Interleukin-17 synergizes with IFNγ or TNFα to promote inflammatory mediator release and intercellular adhesion molecule-1 (ICAM-1) expression in human intervertebral disc cells

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In vivo growth factor treatment of degenerated intervertebral discs

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Potential role of high-mobility group box 1 in cystic fibrosis airway disease.

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Tumor necrosis factor α- and interleukin-1β-dependent induction of CCL3 expression by nucleus pulposus cells promotes macrophage migration through CCR1.

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21 January 2018

Neutrophils contain prolyl endopeptidase and generate the chemotactic peptide, PGP, from collagen

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21 January 2018

Murine nucleus pulposus-derived cells secrete interleukins-1-beta, -6, and -10 and granulocyte-macrophage colony-stimulating factor in cell culture

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21 January 2018

Substance P stimulates production of inflammatory cytokines in human disc cells.

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21 January 2018

Fas ligand plays an important role for the production of pro-inflammatory cytokines in intervertebral disc nucleus pulposus cells

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21 January 2018

Mechanics of the F-actin cytoskeleton

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21 January 2018

Notochordal cells stimulate migration of cartilage end plate chondrocytes of the intervertebral disc in in vitro cell migration assays

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21 January 2018

Expressions of membrane-type I matrix metalloproteinase, Ki-67 protein, and type II collagen by chondrocytes migrating from cartilage endplate into nucleus pulposus in rat intervertebral discs: a cartilage endplate-fracture model using an interverte

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Identifiers

10.1002/STEM.2200

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Europe PubMed Central

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22 February 2020

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22 February 2020

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