Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic. (Q53297957)

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scientific article published in November 2008

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English	Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.	scientific article published in November 2008

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scholarly article

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/18987201

Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic. (English)

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Europe PubMed Central

13 May 2018

http://europepmc.org/abstract/MED/18987201

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Alzheimer's disease

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Sebastian Jimenez

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16 May 2020

David Baglietto-Vargas

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Manuel Torres Canalejo

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Javier Vitorica

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Ines Moreno-Gonzalez

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Antonia Gutierrez

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Antonia Gutierrez

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ORCID Public Data File 2021

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Cristina Caballero

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Raquel Sanchez-Varo

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1 November 2008

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http://europepmc.org/abstract/MED/18987201

Journal of Neuroscience

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16 May 2020

28

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11650-11661

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16 May 2020

The efficiency of systematic sampling in stereology--reconsidered.

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https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

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Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signalin

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https://pubmed.ncbi.nlm.nih.gov/18987201

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Anti-inflammatory therapy for Alzheimer's disease.

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Vaccination with soluble Abeta oligomers generates toxicity-neutralizing antibodies.

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Glial activation in Alzheimer's disease: the role of Abeta and its associated proteins

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Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases.

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Neutralization of TRAIL death pathway protects human neuronal cell line from beta-amyloid toxicity

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Intracranially Administered Anti-Αβ Antibodies Reduce β-Amyloid Deposition by Mechanisms Both Independent of and Associated with Microglial Activation

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Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

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Time sequence of maturation of dystrophic neurites associated with Abeta deposits in APP/PS1 transgenic mice

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Rofecoxib: no effect on Alzheimer's disease in a 1-year, randomized, blinded, controlled study

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Microglial activation facilitates Abeta plaque removal following intracranial anti-Abeta antibody administration

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Tumor necrosis factor death receptor signaling cascade is required for amyloid-beta protein-induced neuron death.

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Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease

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Inflammation occurs early during the Abeta deposition process in TgCRND8 mice

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Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

1 reference

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12 December 2020

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Time-dependent reduction in Abeta levels after intracranial LPS administration in APP transgenic mice.

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Minocycline inhibits apoptotic cell death via attenuation of TNF-alpha expression following iNOS/NO induction by lipopolysaccharide in neuron/glia co-cultures

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Synaptic targeting by Alzheimer's-related amyloid beta oligomers.

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Activation of microglia by aggregated beta-amyloid or lipopolysaccharide impairs MHC-II expression and renders them cytotoxic whereas IFN-gamma and IL-4 render them protective.

1 reference

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12 December 2020

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Vesicle-mediated transport and release of CCL21 in endangered neurons: a possible explanation for microglia activation remote from a primary lesion.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

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Microglial phagocytosis induced by fibrillar beta-amyloid and IgGs are differentially regulated by proinflammatory cytokines.

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Early neuropathology of somatostatin/NPY GABAergic cells in the hippocampus of a PS1xAPP transgenic model of Alzheimer's disease

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Invasion of hematopoietic cells into the brain of amyloid precursor protein transgenic mice.

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Human amyloid beta-induced neuroinflammation is an early event in neurodegeneration

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1 reference

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1 reference

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1 reference

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Monoclonal antibodies that target pathological assemblies of Abeta.

1 reference

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12 December 2020

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inferred from PubMed ID database lookup

Solution state characterization of amyloid beta-derived diffusible ligands

1 reference

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IL-17 family cytokines and the expanding diversity of effector T cell lineages

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory processes in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inter-individual variability in the expression of the mutated form of hPS1M146L determined the production of Abeta peptides in the PS1xAPP transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 attenuates the neuroinflammation induced by amyloid-beta in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

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1 reference

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Toll-like receptor 2 acts as a natural innate immune receptor to clear amyloid beta 1-42 and delay the cognitive decline in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

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Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular and pharmacological characterization of native cortical gamma-aminobutyric acidA receptors containing both alpha1 and alpha3 subunits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glial-neuronal interactions in Alzheimer's disease: the potential role of a 'cytokine cycle' in disease progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18987201

12 December 2020

based on heuristic

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Identifiers

10.1523/JNEUROSCI.3024-08.2008

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671312&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671312&resulttype=core&format=json

16 May 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6671312&resulttype=core&format=json

16 May 2020

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