Pharmacokinetics of the M1-agonist talsaclidine in mouse, rat, rabbit and monkey, and extrapolation to man. (Q53238361)

12 May 2018

title

Pharmacokinetics of the M1-agonist talsaclidine in mouse, rat, rabbit and monkey, and extrapolation to man. (English)

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12 May 2018

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Leusch A

1

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12 May 2018

Tröger W

series ordinal

2

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12 May 2018

Greischel A

series ordinal

3

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12 May 2018

Roth W

series ordinal

4

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12 May 2018

language of work or name

English

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publication date

1 August 2000

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12 May 2018

published in

Xenobiotica

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12 May 2018

volume

30

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issue

8

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12 May 2018

page(s)

797-813

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12 May 2018

Discriminative stimulus properties of the muscarinic receptor agonists Lu 26-046 and O-Me-THPO in rats: evidence for involvement of different muscarinic receptor subtypes

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Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.

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Correlation of plasma clearance of 54 extensively metabolized drugs between humans and rats: mean allometric coefficient of 0.66.

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Invited review: Cholinesterase inhibitors for Alzheimer's disease therapy: from tacrine to future applications

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Link between drug absorption solubility and permeability measurements in Caco-2 cells

21 January 2018

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Donepezil improves cognition and global function in Alzheimer disease: a 15-week, double-blind, placebo-controlled study. Donepezil Study Group.

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A bridging study of LU 25-109 in patients with probable Alzheimer's disease

21 January 2018

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Specificity of transporters for 'organic anions' and 'organic cations' in the kidney

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Tacrine in Alzheimer's disease

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Physiological parameters in laboratory animals and humans

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10.1080/00498250050119853

21 January 2018

Identifiers

DOI

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12 May 2018

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12 May 2018