Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications. (Q53215699)

12 May 2018

title

Apolipoprotein E, A beta-amyloid, and the molecular pathology of Alzheimer's disease. Therapeutic implications. (English)

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12 May 2018

author

Gunnar K. Gouras

2

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12 May 2018

Paul Greengard

6

object named as

Greengard P

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12 May 2018

Kaplitt M

1

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Makimura H

3

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Jovanovic J

4

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Sweeney D

5

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Relkin NR

7

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Gandy S

8

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language of work or name

English

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publication date

1 December 1996

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12 May 2018

Annals of the New York Academy of Sciences

published in

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12 May 2018

volume

802

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12 May 2018

page(s)

42-49

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12 May 2018

Severe hypercholesterolemia and atherosclerosis in apolipoprotein E-deficient mice created by homologous recombination in ES cells

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Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease

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Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

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Peptides homologous to the amyloid protein of Alzheimer's disease containing a glutamine for glutamic acid substitution have accelerated amyloid fibril formation.

21 January 2018

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Evidence that beta-amyloid protein in Alzheimer's disease is not derived by normal processing

21 January 2018

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Cleavage of amyloid beta peptide during constitutive processing of its precursor

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Amyloid beta-peptide is produced by cultured cells during normal metabolism

21 January 2018

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Isolation and quantification of soluble Alzheimer's beta-peptide from biological fluids

21 January 2018

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Production of the Alzheimer amyloid beta protein by normal proteolytic processing

21 January 2018

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21 January 2018

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Expression of apolipoprotein E during nerve degeneration and regeneration

21 January 2018

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Hypothesis: microtubule instability and paired helical filament formation in the Alzheimer disease brain are related to apolipoprotein E genotype

21 January 2018

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Genetic associations with human longevity at the APOE and ACE loci.

21 January 2018

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Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

21 January 2018

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21 January 2018

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Protection against Alzheimer's disease with apoE epsilon 2.

21 January 2018

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Frequency of the apolipoprotein E epsilon 2 allele is diminished in sporadic Alzheimer disease.

21 January 2018

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Solvation Effects on the Conformational Behaviour of Gellan and Calcium Ion Binding to Gellan Double Helices

21 January 2018

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Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments

21 January 2018

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Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3

21 January 2018

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1749-6632.1996.TB32597.X

Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1749-6632.1996.TB32597.X

Isolation and characterization of apolipoprotein E

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1749-6632.1996.TB32597.X

Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1749-6632.1996.TB32597.X

Apolipoprotein E associated with astrocytic glia of the central nervous system and with nonmyelinating glia of the peripheral nervous system

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1749-6632.1996.TB32597.X

Apolipoprotein E, epsilon 4 allele as a major risk factor for sporadic early and late-onset forms of Alzheimer's disease: analysis of the 19q13.2 chromosomal region.

1 reference

12 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1111/J.1749-6632.1996.TB32597.X

Identifiers

DOI

10.1111/J.1749-6632.1996.TB32597.X

1 reference

12 May 2018

PubMed ID

8993483

1 reference

12 May 2018