First-in-human study of the toxicity, pharmacokinetics, and pharmacodynamics of CG200745, a pan-HDAC inhibitor, in patients with refractory solid malignancies. (Q53212463)

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scientific article published on 17 June 2015

Language	Label	Description	Also known as
English	First-in-human study of the toxicity, pharmacokinetics, and pharmacodynamics of CG200745, a pan-HDAC inhibitor, in patients with refractory solid malignancies.	scientific article published on 17 June 2015

Statements

scholarly article

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/26076682

First-in-human study of the toxicity, pharmacokinetics, and pharmacodynamics of CG200745, a pan-HDAC inhibitor, in patients with refractory solid malignancies. (English)

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/26076682

pharmacodynamics

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

6

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26076682%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Kyu-pyo Kim

1

1 reference

Europe PubMed Central

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13 June 2020

Seong Joon Park

2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26076682%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Jeong-Eun Kim

3

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26076682%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Yong Sang Hong

4

1 reference

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13 June 2020

Jae-Lyun Lee

5

1 reference

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13 June 2020

Hyunju Cha

7

1 reference

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13 June 2020

Sool-Ki Kwon

8

1 reference

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13 June 2020

Seonggu Ro

9

1 reference

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13 June 2020

JoongMyung Cho

10

1 reference

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13 June 2020

Tae Won Kim

11

1 reference

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13 June 2020

publication date

17 June 2015

1 reference

Europe PubMed Central

12 May 2018

http://europepmc.org/abstract/MED/26076682

Investigational New Drugs

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Europe PubMed Central

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13 June 2020

33

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13 June 2020

5

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13 June 2020

1048-1057

1 reference

Europe PubMed Central

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13 June 2020

https://scigraph.springernature.com/pub.10.1007/s10637-015-0262-2

0 references

Anticancer activities of histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

Clinical Toxicities of Histone Deacetylase Inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

Thrombocytopenia induced by the histone deacetylase inhibitor abexinostat involves p53-dependent and -independent mechanisms.

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

Assays for pharmacodynamic analysis of histone deacetylase inhibitors

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

Histone deacetylase inhibitors and colorectal cancer: what is new?

1 reference

https://api.crossref.org/works/10.1007%2FS10637-015-0262-2

21 January 2018

American Society of Clinical Oncology policy statement update: the critical role of phase I trials in cancer research and treatment

1 reference

https://pubmed.ncbi.nlm.nih.gov/26076682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of the HDAC inhibitor CG2 in combination with irinotecan, 5-fluorouracil, or oxaliplatin on HCT116 colon cancer cells and xenografts.

1 reference

https://pubmed.ncbi.nlm.nih.gov/26076682

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S10637-015-0262-2

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26076682%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26076682%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

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