Evolving trends in mAb production processes. (Q52724995)

6 May 2018

title

Evolving trends in mAb production processes. (English)

1 reference

6 May 2018

author name string

Abhinav A Shukla

1

1 reference

6 May 2018

Leslie S Wolfe

2

1 reference

6 May 2018

Sigma S Mostafa

3

1 reference

6 May 2018

Carnley Norman

4

1 reference

6 May 2018

publication date

1 March 2017

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6 May 2018

Bioengineering & Translational Medicine

published in

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6 May 2018

volume

2

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6 May 2018

issue

1

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6 May 2018

page(s)

58-69

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6 May 2018

From gene to harvest: insights into upstream process development for the GMP production of a monoclonal antibody in transgenic tobacco plants

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The therapeutic monoclonal antibody market

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22 May 2018

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Microbials for the production of monoclonal antibodies and antibody fragments.

22 May 2018

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Purification of monoclonal antibodies by hydrophobic interaction chromatography under no-salt conditions

22 May 2018

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Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems

22 May 2018

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Single-use disposable technologies for biopharmaceutical manufacturing

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Dual targeting strategies with bispecific antibodies

22 May 2018

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Aglycosylated antibodies and antibody fragments produced in a scalable in vitro transcription-translation system

22 May 2018

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Advances in the production and downstream processing of antibodies

22 May 2018

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Aggregates in monoclonal antibody manufacturing processes

22 May 2018

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Metrics for antibody therapeutics development

22 May 2018

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Strategies for high-level recombinant protein expression in transgenic microalgae: a review

22 May 2018

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Cell culture processes for monoclonal antibody production

22 May 2018

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Recent advances in large-scale production of monoclonal antibodies and related proteins

22 May 2018

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Industrialization of mAb production technology: the bioprocessing industry at a crossroads

22 May 2018

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Follow-on protein products: scientific issues, developments and challenges

22 May 2018

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Production of recombinant proteins by microbes and higher organisms

22 May 2018

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Chromatography-free recovery of biopharmaceuticals through aqueous two-phase processing.

22 May 2018

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A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?

22 May 2018

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Production of recombinant proteins in transgenic plants: Practical considerations

22 May 2018

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Bioseparation in antibody manufacturing: the good, the bad and the ugly

22 May 2018

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Very large scale monoclonal antibody purification: the case for conventional unit operations

22 May 2018

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FcRn: the neonatal Fc receptor comes of age.

22 May 2018

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The use of chitosan as a flocculant in mammalian cell culture dramatically improves clarification throughput without adversely impacting monoclonal antibody recovery

22 May 2018

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Alternatives to chromatographic separations

22 May 2018

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Downstream processing of monoclonal antibodies--application of platform approaches

22 May 2018

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22 May 2018

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Basic concepts in Q membrane chromatography for large-scale antibody production

22 May 2018

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Anticalins as an alternative to antibody technology

22 May 2018

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Production technologies for monoclonal antibodies and their fragments

22 May 2018

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Plant-based production of biopharmaceuticals

22 May 2018

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22 May 2018

Engineered antibodies

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An efficient route to human bispecific IgG.

22 May 2018

1 reference

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Trends in Upstream and Downstream Process Development for Antibody Manufacturing

22 May 2018

1 reference

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End-to-end integrated fully continuous production of recombinant monoclonal antibodies.

13 August 2018

1 reference

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A comparison of protein A chromatographic stationary phases: performance characteristics for monoclonal antibody purification.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Antibody-drug conjugates.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Continuous purification of antibodies from cell culture supernatant with aqueous two-phase systems: from concept to process.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Periodic counter-current chromatography -- design and operational considerations for integrated and continuous purification of proteins.

13 August 2018

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Integrated continuous production of recombinant therapeutic proteins.

13 August 2018

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Therapeutic Fc-fusion proteins and peptides as successful alternatives to antibodies

13 August 2018

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Integrated single-cell analysis shows Pichia pastoris secretes protein stochastically.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Design of a filter train for precipitate removal in monoclonal antibody downstream processing.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Host cell protein clearance during protein A chromatography: development of an improved column wash step.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Selective antibody precipitation using polyelectrolytes: a novel approach to the purification of monoclonal antibodies.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Weak partitioning chromatography for anion exchange purification of monoclonal antibodies.

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

Demonstration of robust host cell protein clearance in biopharmaceutical downstream processes

13 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5689530

The impact of Fc engineering on an anti-CD19 antibody: increased Fcgamma receptor affinity enhances B-cell clearing in nonhuman primates

13 August 2018

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12 December 2020

Application of a PEG/salt aqueous two-phase partition system for the recovery of monoclonal antibodies from unclarified transgenic tobacco extract

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12 December 2020

Caprylic acid precipitation method for impurity reduction: an alternative to conventional chromatography for monoclonal antibody purification

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12 December 2020

The need for innovation in biomanufacturing

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12 December 2020

Multimodal chromatography: Characterization of protein binding and selectivity enhancement through mobile phase modulators

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12 December 2020

Progress and Hurdles for Follow-on Biologics

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12 December 2020

The business impact of an integrated continuous biomanufacturing platform for recombinant protein production

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12 December 2020

Identifiers

DOI

10.1002/BTM2.10061

1 reference

6 May 2018

PMCID

5689530

1 reference

6 May 2018

PubMed ID

29313024

1 reference

6 May 2018