Inhibition, activation, destruction, and induction of drug-metabolizing enzymes by trichloroethylene (Q52702252)

6 May 2018

title

Inhibition, activation, destruction, and induction of drug-metabolizing enzymes by trichloroethylene (English)

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6 July 2022

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10 June 2023

author name string

D. Pessayre

1

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6 July 2022

H. Allemand

2

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6 July 2022

J. C. Wandscheer

3

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6 July 2022

V. Descatoire

4

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6 July 2022

J. Y. Artigou

5

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6 July 2022

J. P. Benhamou

6

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6 July 2022

language of work or name

English

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National Center for Biotechnology Information

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6 July 2022

publication date

1 June 1979

1 reference

6 May 2018

30 June 1979

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National Center for Biotechnology Information

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full work available at URL

6 July 2022

https://api.elsevier.com/content/article/PII:0041008X79902606?httpAccept=text/xml

1 reference

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https://api.elsevier.com/content/article/PII:0041008X79902606?httpAccept=text/plain

10 June 2023

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Toxicology and Applied Pharmacology

10 June 2023

published in

1 reference

6 May 2018

volume

49

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6 May 2018

issue

2

1 reference

6 May 2018

page(s)

355-363

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6 May 2018

Metabolic activation of trichloroethylene into a chemically reactive metabolite toxic to the liver

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10 June 2023

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Incubation of 14C-trichloroethylene vapor with rat liver microsomes: uptake of radioactivity and covalent protein binding of metabolites

10 June 2023

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Irreversible binding of chlorinated ethylenes to macromolecules

10 June 2023

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Chemical reactivity, metabolic oxirane formation and biological reactivity of chlorinated ethylenes in the isolated perfused rat liver preparation

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Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation

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Relative effects of various chlorinated hydrocarbons on liver and kidney function in dogs

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A sensitive radioactive assay for hexobarbital hydroxylase in hepatic microsomes

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Trichloroethylene-induced deactivation of cytochrome P-450 and loss of liver glutathione in vivo

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Enhancement of the metabolism and hepatotoxicity of trichloroethylene and perchloroethylene

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Induction and inhibition of hepatic drug metabolizing enzymes by rifampin

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Activation of hepatic microsomal glucuronyl transferase by bilirubin.

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Trichloroethylene and 1,1,1-trichloroethane: effects on brain and liver after five days intermittent inhalation

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Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro

10 June 2023

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Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation

10 June 2023

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Covalent interaction of metabolites of the carcinogen trichloroethylene in rat hepatic microsomes

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Studies on the activation in vitro of glucuronyltranferase

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10 June 2023

Identifiers

1 reference

6 May 2018

1 reference

6 May 2018