2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization. (Q52664543)

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scientific article published on 9 March 2018

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English	2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization.	scientific article published on 9 March 2018

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scholarly article

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19 March 2020

2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization (English)

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19 March 2020

Mycobacterium tuberculosis

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Clifton E Barry

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Valerie Mizrahi

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Dirk A. Lamprecht

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Helena I M Boshoff

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Kyu Y Rhee

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Thomas R Ioerger

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Thomas R Ioerger

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Maria Osuna-Cabello

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Maria Osuna-Cabello

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Jennifer Riley

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19 March 2020

author name string

Dinakaran Murugesan

1

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19 March 2020

Peter C Ray

2

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19 March 2020

Tracy Bayliss

3

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19 March 2020

Gareth A Prosser

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19 March 2020

Justin R Harrison

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19 March 2020

Kirsteen Green

6

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19 March 2020

Candice Soares de Melo

7

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19 March 2020

Tzu-Shean Feng

8

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Leslie J Street

9

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19 March 2020

Ola Epemolu

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19 March 2020

Paul Scullion

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19 March 2020

Lucy Ellis

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19 March 2020

Yoko Shishikura

17

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19 March 2020

Liam Ferguson

18

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19 March 2020

Kevin D Read

20

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19 March 2020

Simon R Green

21

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19 March 2020

Peter M Finin

23

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19 March 2020

Jim Sacchettini

26

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Kriti Arora

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publication date

26 March 2018

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19 March 2020

ACS Infectious Diseases

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19 March 2020

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19 March 2020

954-969

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19 March 2020

6

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19 March 2020

Susceptibility of Mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c.

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3 July 2018

Rational Design, Synthesis, and Biological Evaluation of Heterocyclic Quinolones Targeting the Respiratory Chain of Mycobacterium tuberculosis

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Mycobacterium tuberculosis type II NADH-menaquinone oxidoreductase catalyzes electron transfer through a two-site ping-pong mechanism and has two quinone-binding sites

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Identifiers

10.1021/ACSINFECDIS.7B00275

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19 March 2020

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