Destruxins, cyclodepsipeptides, block the formation of actin rings and prominent clear zones and ruffled borders in osteoclasts. (Q52551920)

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16 December 2019

title

Destruxins, cyclodepsipeptides, block the formation of actin rings and prominent clear zones and ruffled borders in osteoclasts (English)

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16 December 2019

2

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Masaaki Wachi

8

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16 December 2019

author name string

H Nakagawa

1

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16 December 2019

N Udagawa

3

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16 December 2019

Y Sawae

4

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16 December 2019

K Suda

5

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16 December 2019

T Sasaki

6

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16 December 2019

N Takahashi

7

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K Nagai

9

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J T Woo

10

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16 December 2019

publication date

1 September 2003

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16 December 2019

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16 December 2019

volume

33

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16 December 2019

issue

3

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page(s)

443-455

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Modulation of osteoclast differentiation

16 December 2019

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Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts

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Osteoblastic cells induce fusion and activation of osteoclasts through a mechanism independent of macrophage-colony-stimulating factor production

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omega-Conotoxin GVIA and nifedipine inhibit the depolarizing action of the fungal metabolite, destruxin B on muscle from the tobacco budworm (Heliothis virescens).

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Comparison of the phytotoxic activity of the phytotoxin destruxin B and four natural analogs

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In vitro effect of fungal cyclodepsipeptides on leukemic cells: study of destruxins A, B and E

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Suppressive effects of destruxin B on hepatitis B virus surface antigen gene expression in human hepatoma cells

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Study of structure-activity correlation in destruxins, a class of cyclodepsipeptides possessing suppressive effect on the generation of hepatitis B virus surface antigen in human hepatoma cells

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Suppressive effects of metabolites from Alternaria brassicaea on the hepatitis B surface antigen

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Phosphatidylinositol-3 kinase is involved in ruffled border formation in osteoclasts

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7 January 2021

Wortmannin, a specific inhibitor of phosphatidylinositol-3 kinase, blocks osteoclastic bone resorption.

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7 January 2021

Compactin suppresses bone resorption by inhibiting the fusion of prefusion osteoclasts and disrupting the actin ring in osteoclasts.

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Rho-A is critical for osteoclast podosome organization, motility, and bone resorption

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7 January 2021

Destruxin B, a specific and readily reversible inhibitor of vacuolar-type H(+)-translocating ATPase

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7 January 2021

Effects of efrapeptin and destruxin, metabolites of entomogenous fungi, on the hydrolytic activity of a vacuolar type ATPase identified on the brush border membrane vesicles of Galleria mellonella midgut and on plant membrane bound hydrolytic enzyme

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Characterization of a series of vacuolar type H(+)-ATPase inhibitors on CTL-mediated cytotoxicity

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Inhibition of the accumulation of lipid droplets in macrophage J774 by bafilomycin B1 and destruxin E.

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Destruxin-A4 chlorohydrin, a novel destruxin from fungus OS-F68576: isolation, structure determination, and biological activity as an inducer of erythropoietin

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Identifiers

DOI

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16 December 2019

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