An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. (Q52511681)

2 May 2018

title

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice. (English)

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2 May 2018

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5

Tonegawa S

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2 May 2018

author name string

Mombaerts P

1

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2 May 2018

Anderson SJ

2

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2 May 2018

Perlmutter RM

3

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2 May 2018

Mak TW

4

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2 May 2018

language of work or name

English

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publication date

1 July 1994

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2 May 2018

published in

Immunity

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2 May 2018

volume

1

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2 May 2018

issue

4

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2 May 2018

page(s)

261-267

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2 May 2018

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

cites work

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

A role for a pre-T-cell receptor in T-cell development

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11 October 2022

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Control points in early T-cell development

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11 October 2022

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A novel disulfide-linked heterodimer on pre-T cells consists of the T cell receptor beta chain and a 33 kd glycoprotein

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Profound block in thymocyte development in mice lacking p56lck

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

The protein tyrosine kinase p56lck regulates thymocyte development independently of its interaction with CD4 and CD8 coreceptors [corrected]

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

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11 October 2022

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Protein tyrosine kinase p56 lck controls allelic exclusion of T-cell receptor β-chain genes

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11 October 2022

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In transgenic mice the introduced functional T cell receptor beta gene prevents expression of endogenous beta genes.

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11 October 2022

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Surface expression of a T cell receptor beta (TCR-beta) chain in the absence of TCR-alpha, -delta, and -gamma proteins

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11 October 2022

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The SCID mouse mutant: definition, characterization, and potential uses

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Regulation of lymphocyte function by protein phosphorylation

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11 October 2022

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Alloreactive cytotoxic T cells can develop and function in mice lacking both CD4 and CD8.

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11 October 2022

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T-cell differentiation under control

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11 October 2022

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Inhibition of T-cell receptor beta-chain gene rearrangement by overexpression of the non-receptor protein tyrosine kinase p56lck

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11 October 2022

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T cell receptor beta chain dimers on immature thymocytes from normal mice

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11 October 2022

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T cell depletion in transgenic mice carrying a mutant gene for TCR-β

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11 October 2022

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Lymphoid development in mice congenitally lacking T cell receptor alpha beta-expressing cells

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11 October 2022

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Dismantling the immune system

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11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Somatic generation of antibody diversity

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

T-cell antigen receptor genes and T-cell recognition

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Involvement of the protein tyrosine kinase p56lck in T cell signaling and thymocyte development.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

The V(D)J recombination activating gene, RAG-1.

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1016/1074-7613(94)90077-9

Identifiers

DOI

10.1016/1074-7613(94)90077-9

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2 May 2018

PubMed ID

7889413

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2 May 2018