Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation. (Q52431415)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29632189%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

title

Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation (English)

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22 March 2020

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3

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22 March 2020

Lai Wei

12

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22 March 2020

13

Arthur Weiss

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22 March 2020

11

Michael T McManus

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22 March 2020

author name string

Wanjing Shang

1

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22 March 2020

Yong Jiang

2

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22 March 2020

Kang Ding

4

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22 March 2020

Marianne Mollenauer

5

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22 March 2020

Zhongyi Liu

6

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22 March 2020

Xiaofeng Wen

7

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22 March 2020

Chang Liu

8

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22 March 2020

Piliang Hao

9

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22 March 2020

Suwen Zhao

10

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22 March 2020

Haopeng Wang

14

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22 March 2020

language of work or name

English

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publication date

9 April 2018

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Proceedings of the National Academy of Sciences of the United States of America

22 March 2020

published in

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22 March 2020

volume

115

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22 March 2020

page(s)

E4051-E4060

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22 March 2020

issue

17

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TCR Signaling: Mechanisms of Initiation and Propagation.

22 March 2020

cites work

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25 August 2018

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Key elements for designing and performing a CRISPR/Cas9-based genetic screen.

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25 August 2018

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25 August 2018

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25 August 2018

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25 August 2018

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25 August 2018

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25 August 2018

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25 August 2018

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DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

25 August 2018

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25 August 2018

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25 August 2018

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25 August 2018

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T cell receptor signalling

25 August 2018

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Rac is involved in early TCR signaling

25 August 2018

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A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK

25 August 2018

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The crystal structure of human rac1, a member of the rho-family complexed with a GTP analogue

25 August 2018

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Sustained signaling leading to T cell activation results from prolonged T cell receptor occupancy. Role of T cell actin cytoskeleton

25 August 2018

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25 August 2018

Identifiers

DOI

10.1073/PNAS.1801340115

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29632189%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29632189%20AND%20SRC:MED&resulttype=core&format=json

22 March 2020

1 reference