Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure. (Q52319052)

29 April 2018

title

Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure. (English)

1 reference

29 April 2018

Collaborative Research Centre (CRC) 1002: "Modulatory Units in Heart Failure"

sponsor

0 references

author name string

Björn Tampe

1

1 reference

29 April 2018

Désirée Tampe

2

1 reference

29 April 2018

Gunsmaa Nyamsuren

3

1 reference

29 April 2018

Friederike Klöpper

4

1 reference

29 April 2018

Gregor Rapp

5

1 reference

29 April 2018

Anne Kauffels

6

1 reference

29 April 2018

Thomas Lorf

7

1 reference

29 April 2018

Elisabeth M Zeisberg

8

1 reference

29 April 2018

Gerhard A Müller

9

1 reference

29 April 2018

Raghu Kalluri

10

1 reference

29 April 2018

Samy Hakroush

11

1 reference

29 April 2018

Michael Zeisberg

12

1 reference

29 April 2018

language of work or name

English

0 references

publication date

17 April 2018

1 reference

29 April 2018

Journal of Clinical Investigation

published in

1 reference

29 April 2018

Pretreatment Combination Reduces Remote Organ Damage Secondary to Intestinal Reperfusion Injury in Mice: Follow-up Study.

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Tissue transcriptome-driven identification of epidermal growth factor as a chronic kidney disease biomarker

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Morpholinos: Antisense and Sensibility

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Molecular Markers of Tubulointerstitial Fibrosis and Tubular Cell Damage in Patients with Chronic Kidney Disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Molecular mechanisms of ischemic preconditioning in the kidney

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Transgenic over-expression of YY1 induces pathologic cardiac hypertrophy in a sex-specific manner

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

STRING v10: protein-protein interaction networks, integrated over the tree of life

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Cytosine methylation changes in enhancer regions of core pro-fibrotic genes characterize kidney fibrosis development

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Ischemic preconditioning and tacrolimus pretreatment as strategies to attenuate intestinal ischemia-reperfusion injury in mice.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

FK506 activates BMPR2, rescues endothelial dysfunction, and reverses pulmonary hypertension.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Novel mechanism of regulation of fibrosis in kidney tumor with tuberous sclerosis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Bone morphogenetic protein-7 inhibits silica-induced pulmonary fibrosis in rats

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Angiotensin II-induced cardiac hypertrophy and fibrosis are promoted in mice lacking Fgf16.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

YY1TargetDB: an integral information resource for Yin Yang 1 target loci

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Yin Yang 1 promotes hepatic steatosis through repression of farnesoid X receptor in obese mice.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Transcriptome analysis of human diabetic kidney disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Protective effect of FK506 on myocardial ischemia/reperfusion injury by suppression of CaN and ASK1 signaling circuitry.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

A molecular signature of proteinuria in glomerulonephritis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Genome-wide analysis of YY2 versus YY1 target genes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Graft preconditioning with low-dose tacrolimus (FK506) and nitric oxide inhibitor aminoguanidine (AGH) reduces ischemia/reperfusion injury after liver transplantation in the rat.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Pharmacological preconditioning of random-pattern skin flaps with local FK506 in nicotine-treated rats: interaction with nitric oxide system.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Reduced exposure to calcineurin inhibitors in renal transplantation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Endothelial-to-mesenchymal transition contributes to cardiac fibrosis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Predicting transcription factor affinities to DNA from a biophysical model.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Gene expression analyses reveal molecular relationships among 20 regions of the human CNS.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Kidney transplant rejection and tissue injury by gene profiling of biopsies and peripheral blood lymphocytes

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Comparison of the pharmacokinetics of tacrolimus and cyclosporine at equivalent molecular doses

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Multiple mechanisms of transcriptional repression by YY1.

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

DNA binding specificities and pairing rules of the Ah receptor, ARNT, and SIM proteins

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Characterization of a renal tubular epithelial cell line which secretes the autologous target antigen of autoimmune experimental interstitial nephritis

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

The protective effect of FK506 pretreatment against renal ischemia/reperfusion injury in rats

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

The mechanism of action of cyclosporin A and FK506

25 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6025987

Immunophilins mediate the neuroprotective effects of FK506 in focal cerebral ischaemia

25 August 2018

1 reference

12 December 2020

Constitutive function of the basic helix-loop-helix/PAS factor Arnt. Regulation of target promoters via the E box motif

1 reference

12 December 2020

Distinct patterns of cytokine gene suppression by the equivalent effective doses of cyclosporine and tacrolimus in rat heart allografts

1 reference

12 December 2020

Ischemic preconditioning provides both acute and delayed protection against renal ischemia and reperfusion injury in mice

1 reference

12 December 2020

Modular activation of nuclear factor-kappaB transcriptional programs in human diabetic nephropathy

1 reference

12 December 2020

[Protective effect of tacrolimus postconditioning on oxidative stress injury provoked by spinal cord ischemia-reperfusion in rats]

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI89632

1 reference

29 April 2018

0 references

1 reference

29 April 2018