LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. (Q52309452)

29 April 2018

title

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. (English)

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29 April 2018

0 references

1 reference

Elodie Lafont

12

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Silvia Alvarez-Díaz

Silvia Alvarez-Diaz

18

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Philippe Bouillet

Philippe Bouillet

26

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Andreas Strasser

Andreas Strasser

24

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Peter Draber

Peter Draber

4

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Tariq Enver

21

Tariq Enver

1 reference

29 April 2018

Nieves Peltzer

1

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29 April 2018

Maurice Darding

2

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29 April 2018

Antonella Montinaro

3

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Helena Draberova

5

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29 April 2018

Sebastian Kupka

6

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29 April 2018

Eva Rieser

7

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29 April 2018

Amanda Fisher

8

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29 April 2018

Ciaran Hutchinson

9

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29 April 2018

Lucia Taraborrelli

10

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29 April 2018

Torsten Hartwig

11

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29 April 2018

Tobias L Haas

13

1 reference

29 April 2018

Yutaka Shimizu

14

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29 April 2018

Charlotta Böiers

15

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29 April 2018

Aida Sarr

16

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29 April 2018

James Rickard

17

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29 April 2018

Michael T Ashworth

19

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29 April 2018

Allison Beal

20

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29 April 2018

John Bertin

22

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29 April 2018

William Kaiser

23

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29 April 2018

John Silke

25

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29 April 2018

Henning Walczak

27

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29 April 2018

language of work or name

English

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publication date

25 April 2018

1 reference

29 April 2018

published in

Nature

1 reference

29 April 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5947819/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/s41586-018-0064-8

0 references

cites work

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Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases.

29 September 2018

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Stress and Non-Stress Roles of Inflammatory Signals during HSC Emergence and Maintenance

29 September 2018

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The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

29 September 2018

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Holding RIPK1 on the Ubiquitin Leash in TNFR1 Signaling

29 September 2018

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Linear ubiquitination in immunity

29 September 2018

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Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia

29 September 2018

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TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice.

29 September 2018

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Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

29 September 2018

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HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.

29 September 2018

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Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis

29 September 2018

1 reference

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Cutting Edge: RIP1 kinase activity is dispensable for normal development but is a key regulator of inflammation in SHARPIN-deficient mice.

29 September 2018

1 reference

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RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.

29 September 2018

1 reference

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The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism

29 September 2018

1 reference

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Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5947819

Defective immune responses in mice lacking LUBAC-mediated linear ubiquitination in B cells.

29 September 2018

1 reference

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Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency

29 September 2018

1 reference

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LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

29 September 2018

1 reference

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Survival function of the FADD-CASPASE-8-cFLIP(L) complex

29 September 2018

1 reference

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Specific recognition of linear ubiquitin chains by the Npl4 zinc finger (NZF) domain of the HOIL-1L subunit of the linear ubiquitin chain assembly complex

29 September 2018

1 reference

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Linear ubiquitination prevents inflammation and regulates immune signalling

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5947819

Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis

29 September 2018

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RIP3 mediates the embryonic lethality of caspase-8-deficient mice

29 September 2018

1 reference

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Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5947819

Involvement of linear polyubiquitylation of NEMO in NF-kappaB activation

29 September 2018

1 reference

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Kinase RIP3 is dispensable for normal NF-kappa Bs, signaling by the B-cell and T-cell receptors, tumor necrosis factor receptor 1, and Toll-like receptors 2 and 4.

29 September 2018

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Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity

29 September 2018

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Tie-1-directed expression of Cre recombinase in endothelial cells of embryoid bodies and transgenic mice

29 September 2018

1 reference

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

29 September 2018

1 reference

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Checkpoints in TNF-Induced Cell Death: Implications in Inflammation and Cancer

29 September 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FS41586-018-0064-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/S41586-018-0064-8

1 reference

29 April 2018

0 references

1 reference

29 April 2018