A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila. (Q52199100)

26 April 2018

title

A gradient of cytoplasmic Cactus degradation establishes the nuclear localization gradient of the dorsal morphogen in Drosophila. (English)

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26 April 2018

main subject

Cactus Dmel_CG5848

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Pelle Dmel_CG5974

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Dorsal Dmel_CG6667

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Toll Dmel_CG5490

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Christiane Nüsslein-Volhard

author

8

object named as

Nüsslein-Volhard C

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26 April 2018

author name string

Bergmann A

1

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26 April 2018

Stein D

2

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26 April 2018

Geisler R

3

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26 April 2018

Hagenmaier S

4

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26 April 2018

Schmid B

5

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26 April 2018

Fernandez N

6

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26 April 2018

Schnell B

7

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26 April 2018

publication date

1 November 1996

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26 April 2018

Mechanisms of Development

published in

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26 April 2018

volume

60

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26 April 2018

page(s)

109-123

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26 April 2018

issue

1

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26 April 2018

I kappa B: a specific inhibitor of the NF-kappa B transcription factor

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Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation

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7 January 2021

Cactus protein degradation mediates Drosophila dorsal-ventral signaling

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7 January 2021

Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation

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Functional cDNA libraries from Drosophila embryos

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Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation

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Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway

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7 January 2021

Distinct molecular mechanism regulate cell cycle timing at successive stages of Drosophila embryogenesis

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7 January 2021

Drosophila Toll and IL-1 receptor

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7 January 2021

cactus, a gene involved in dorsoventral pattern formation of Drosophila, is related to the I kappa B gene family of vertebrates

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7 January 2021

Dorsal, a Drosophila Rel-like protein, is phosphorylated upon activation of the transmembrane protein Toll

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7 January 2021

Activation of the kinase Pelle by Tube in the dorsoventral signal transduction pathway of Drosophila embryo.

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7 January 2021

Common structural constituents confer I kappa B activity to NF-kappa B p105 and I kappa B/MAD-3.

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7 January 2021

Rapid proteolysis of I kappa B-alpha is necessary for activation of transcription factor NF-kappa B

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7 January 2021

The torso receptor tyrosine kinase can activate Raf in a Ras-independent pathway.

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7 January 2021

Characterization of the Drosophila cactus locus and analysis of interactions between cactus and dorsal proteins

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7 January 2021

The dorsal protein enhances the biosynthesis and stability of the Drosophila I kappa B homologue cactus

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7 January 2021

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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7 January 2021

Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.

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7 January 2021

Signaling pathways that establish the dorsal-ventral pattern of the Drosophila embryo

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7 January 2021

Selective nuclear transport of the Drosophila morphogen dorsal can be established by a signaling pathway involving the transmembrane protein Toll and protein kinase A

1 reference

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7 January 2021

Functional interactions between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal.

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7 January 2021

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

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7 January 2021

Amino acid sequences common to rapidly degraded proteins: the PEST hypothesis

1 reference

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7 January 2021

A gradient of nuclear localization of the dorsal protein determines dorsoventral pattern in the Drosophila embryo.

1 reference

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7 January 2021

cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila.

1 reference

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7 January 2021

The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila.

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7 January 2021

Partial rescue of dorsal, a maternal effect mutation affecting the dorso-ventral pattern of the Drosophila embryo, by the injection of wild-type cytoplasm.

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7 January 2021

Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo

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7 January 2021

The p65 subunit of NF-kappa B regulates I kappa B by two distinct mechanisms

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7 January 2021

pelle encodes a protein kinase required to establish dorsoventral polarity in the Drosophila embryo.

1 reference

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7 January 2021

Dorsal, an embryonic polarity gene in Drosophila, is homologous to the vertebrate proto-oncogene, c-rel.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2896%2900607-7

7 January 2021

Relocalization of the dorsal protein from the cytoplasm to the nucleus correlates with its function.

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2896%2900607-7

7 January 2021

NF-kappa B controls expression of inhibitor I kappa B alpha: evidence for an inducible autoregulatory pathway

1 reference

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7 January 2021

I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa B

1 reference

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7 January 2021

A proteasome inhibitor prevents activation of NF-kappa B and stabilizes a newly phosphorylated form of I kappa B-alpha that is still bound to NF-kappa B

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2896%2900607-7

7 January 2021

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation

1 reference

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7 January 2021

Dissociation of the dorsal-cactus complex and phosphorylation of the dorsal protein correlate with the nuclear localization of dorsal

1 reference

https://api.crossref.org/works/10.1016%2FS0925-4773%2896%2900607-7

7 January 2021

10.1016/S0925-4773(96)00607-7

Identifiers

DOI

1 reference

26 April 2018

PubMed ID

9025065

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26 April 2018