Transcriptional regulation and biological significance of the insulin like growth factor II gene. (Q52180058)

PubMed ID

9925986

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9925986%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

review article

1 reference

title

Transcriptional regulation and biological significance of the insulin like growth factor II gene (English)

1 reference

PubMed ID

9925986

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9925986%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

8

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15 May 2020

Andrew Ward

9

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15 May 2020

author name string

W Engström

1

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15 May 2020

A Shokrai

2

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15 May 2020

K Otte

3

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15 May 2020

M Granérus

4

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15 May 2020

A Gessbo

5

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15 May 2020

P Bierke

6

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15 May 2020

A Madej

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15 May 2020

publication date

1 October 1998

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PubMed ID

9925986

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9925986%20AND%20SRC:MED&resulttype=core&format=json

9 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6647699&resulttype=core&format=json

15 May 2020

volume

31

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15 May 2020

page(s)

173-189

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15 May 2020

issue

5-6

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Role of insulin-like growth factors in embryonic and postnatal growth

15 May 2020

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Insulin-like growth factor II in the mink (Mustela vison): determination of a cDNA nucleotide sequence and developmental regulation of its expression.

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Chromatin structure and imprinting: developmental control of DNase-I sensitivity in the mouse insulin-like growth factor 2 gene.

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Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and trans

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Insulin-like growth factors and ovarian follicular development

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Genomic imprinting of Mash2, a mouse gene required for trophoblast development

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Genomic imprinting and the strange case of the insulin-like growth factor II receptor

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Genomic imprinting of p57KIP2, a cyclin-dependent kinase inhibitor, in mouse

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Developmental regulation of insulin like growth factor II gene expression in the pig.

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The primary structure of the rat insulin-like growth factor II gene region

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Identification of a novel transcription unit in the human insulin-like growth factor-II gene

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Insulin-like growth factor II receptor as a multifunctional binding protein

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Insulin-like growth factor II stimulates cell proliferation through the insulin receptor

21 January 2018

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21 January 2018

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Nucleotide sequence of an ovine insulin-like growth factor-II cDNA.

21 January 2018

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Developmental and tissue-specific regulation of ovine insulin-like growth factor II (IGF-II) mRNA expression.

21 January 2018

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Epigenetic changes at the insulin-like growth factor II/H19 locus in developing kidney is an early event in Wilms tumorigenesis.

21 January 2018

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A conserved structural element in horse and mouse IGF2 genes binds a methylation sensitive factor

21 January 2018

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Insulin-like growth factor II in the horse: determination of a cDNA nucleotide sequence and expression in fetal and adult tissue.

21 January 2018

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21 January 2018

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The human insulin-like growth factor II gene contains two development-specific promoters

21 January 2018

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Differential expression of the human insulin-like growth factor II gene. Characterization of the IGF-II mRNAs and an mRNA encoding a putative IGF-II-associated protein

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Primary structure of human insulin-like growth factor II.

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The liver-specific promoter of the human insulin-like growth factor-II gene contains two negative regulatory elements.

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21 January 2018

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Nucleotide sequence of a 28-kb mouse genomic region comprising the imprinted Igf2 gene.

21 January 2018

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The cis-acting elements involved in endonucleolytic cleavage of the 3' UTR of human IGF-II mRNAs bind a 50 kDa protein

21 January 2018

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Growth-condition-dependent regulation of insulin-like growth factor II mRNA stability

21 January 2018

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Analysis of gene dosage on chromosome 11 in children suffering from Beckwith-Wiedemann syndrome.

21 January 2018

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21 January 2018

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Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)

21 January 2018

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Developmental and tissue-specific expression of a family of transcripts related to rat insulin-like growth factor II mRNA

21 January 2018

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Rat insulin-like growth factor II gene. A single gene with two promoters expressing a multitranscript family.

21 January 2018

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Insulin-like growth factor 2 gene imprinting in clear cell sarcoma of the kidney.

21 January 2018

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Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal.

21 January 2018

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Transactivation of Igf2 in a mouse model of Beckwith-Wiedemann syndrome.

21 January 2018

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The human insulin-like growth factor II leader 1 contains an internal ribosomal entry site

21 January 2018

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A paternal-specific methylation imprint marks the alleles of the mouse H19 gene.

21 January 2018

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A new leader exon identified in the rat insulin-like growth factor II gene

21 January 2018

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Transcriptional deviation of the rat insulin-like growth factor II gene initiated at three alternative leader-exons between neonatal tissues and ascites hepatomas.

21 January 2018

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Genomic imprinting--defusing the ovarian time bomb.

21 January 2018

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Promoter-specific imprinting of the human insulin-like growth factor-II gene

21 January 2018

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Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene

21 January 2018

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Beck-Wiedemann syndrome and Wilms' tumour.

21 January 2018

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Height depends on month of birth.

21 January 2018

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The relative effects of different types of growth factors on DNA replication, mitosis, and cellular enlargement

21 January 2018

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Insulin-like growth factor II signaling through the insulin-like growth factor II/mannose-6-phosphate receptor promotes exocytosis in insulin-secreting cells

21 January 2018

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Generation and Characterization of an IGFBP-7 Antibody: Identification of 31kD IGFBP-7 in Human Biological Fluids and Hs578T Human Breast Cancer Conditioned Media

21 January 2018

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Parent-Specific Gene Expression and the Triploid Endosperm

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An Ordered NotI Fragment Map of Human Chromosome Band 11p15

21 January 2018

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Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway

21 January 2018

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Insulin-like growth factor binding proteins.

21 January 2018

1 reference

12 December 2020

Genomic imprinting: review and relevance to human diseases.

1 reference

12 December 2020

Repression of promoters for the mouse insulin-like growth factor II-encoding gene (Igf-2) by products of the Wilms' tumour suppressor gene wt1

1 reference

12 December 2020

Stimulatory effects of basic fibroblast growth factor on DNA synthesis in the human embryonic cornea

1 reference

12 December 2020

Growth enhancement of transgenic mice expressing human insulin-like growth factor I

1 reference

12 December 2020

Relaxation of insulin-like growth factor-II gene imprinting in human gynecologic tumors

1 reference

12 December 2020

Reactivation of the maternally imprinted IGF2 allele in TGFalpha induced hepatocellular carcinomas in mice

1 reference

12 December 2020

Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes

1 reference

12 December 2020

Overexpression of human insulin-like growth factor-II in transgenic mice causes increased growth of the thymus

1 reference

12 December 2020

Insulin-like growth factors and the multiplication of Tera-2, a human teratoma-derived cell line.

1 reference

12 December 2020

Tissue distribution of insulin-like growth factor I and II messenger ribonucleic acid in the adult rat

1 reference

12 December 2020

Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis.

1 reference

12 December 2020

Transcriptional and post-transcriptional regulation of the human IGF-II gene expression.

1 reference

12 December 2020

Regulation of insulin-like growth factor I receptor gene expression in normal and pathological states.

1 reference

12 December 2020

Stimulatory effect of insulin like growth factor II on DNA synthesis in the human embryonic cornea

1 reference

12 December 2020

Parental genomic imprinting of the human IGF2 gene

1 reference

12 December 2020

A chromatin model of IGF2/H19 imprinting

1 reference

12 December 2020

Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice.

1 reference

12 December 2020

A hormonally controlled serum factor which stimulates sulfate incorporation by cartilage in vitro.

1 reference

12 December 2020

Insulin-like growth factors: growth, transgenes and imprinting

1 reference

12 December 2020

Growth at the Cellular Level

1 reference

12 December 2020

Ancient divergence of insulin and insulin-like growth factor

1 reference

12 December 2020

Characterization of the linked ovine insulin and insulin-like growth factor-II genes

1 reference

12 December 2020

Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice

1 reference

12 December 2020

Developmental regulation of bovine insulin-like growth factor-II (IGF-II) gene expression: homology between bovine transcripts and human IGF-II exons.

1 reference

12 December 2020

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin

1 reference

12 December 2020

Mannose 6-phosphate/insulin-like growth factor II receptor: distinct binding sites for mannose 6-phosphate and insulin-like growth factor II

1 reference

12 December 2020

The insulin-like growth factor II (IGF-II)/mannose 6-phosphate receptor mediates IGF-II-induced motility in human rhabdomyosarcoma cells

1 reference

12 December 2020

A promoter of the rat insulin-like growth factor II gene consists of minimal control elements

1 reference

12 December 2020

Histochemical localization of IGF-I and -II mRNA in the developing rat embryo

1 reference

12 December 2020

Stimulatory effects of insulin-like growth factors on DNA synthesis in the human embryonic cornea.

1 reference

12 December 2020

The human insulin-like growth factor-II promoter P1 is not restricted to liver: evidence for expression of P1 in other tissues and for a homologous promoter in baboon liver

1 reference

12 December 2020

Role of protein phosphatases in insulin-like growth factor II (IGF II)-stimulated mannose 6-phosphate/IGF II receptor redistribution

1 reference

12 December 2020

Solution structure of human insulin-like growth factor II; recognition sites for receptors and binding proteins.

1 reference

12 December 2020

KVLQT1, the rhythm of imprinting

1 reference

12 December 2020

Developmental control of allelic methylation in the imprinted mouse Igf2 and H19 genes.

1 reference

12 December 2020

IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndrome

1 reference

12 December 2020

Parental imprinting of rat insulin-like growth factor II gene promoters is coordinately regulated

1 reference

12 December 2020

Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1

1 reference

12 December 2020

Somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II mRNAs in rat fetal and adult tissues

1 reference

12 December 2020

Expression and characterization of a functional human insulin-like growth factor I receptor

1 reference

12 December 2020

Translational discrimination of mRNAs coding for human insulin-like growth factor II

1 reference

12 December 2020

Loss of imprinting of igf2 in renal-cell carcinomas

1 reference

12 December 2020

Concordant loss of imprinting of the human insulin-like growth factor II gene promoters in cancer

1 reference

12 December 2020

1H-NMR Assignment and Secondary Structure of Human Insulin-Like Growth Factor-I(IGF-I) in Solution

1 reference

12 December 2020

Molecular analysis of patients with Wiedemann-Beckwith syndrome. I. Gene dosage on the short arm of chromosome 11

1 reference

12 December 2020

IGF2 but not H19 shows loss of imprinting in human glioma.

1 reference

12 December 2020

Insulin-like growth factor II prevents apoptosis in a human teratoma derived cell line

1 reference

12 December 2020

Structure and expression of the rat insulin-like growth factor II (rIGF-II) gene. rIGF-II RNAs are transcribed from two promoters

1 reference

12 December 2020

Growth factors and apoptosis

1 reference

12 December 2020

Modulation of human basophil histamine release by insulin-like growth factors

1 reference

12 December 2020

Generation and characterization of an IGFBP-7 antibody: identification of 31kD IGFBP-7 in human biological fluids and Hs578T human breast cancer conditioned media

1 reference

12 December 2020

"Spontaneous" differentiation of skeletal myoblasts is dependent upon autocrine secretion of insulin-like growth factor-II

1 reference

12 December 2020

The insulin-like growth factor-I receptor. Structure, ligand-binding mechanism and signal transduction.

1 reference

12 December 2020

Pattern of the insulin-like growth factor II gene expression during early mouse embryogenesis

1 reference

12 December 2020

Solution structure of human insulin-like growth factor II. Relationship to receptor and binding protein interactions

1 reference

12 December 2020

Location of enhancers is essential for the imprinting of H19 and Igf2 genes

1 reference

12 December 2020

Rescue of the T-associated maternal effect in mice carrying null mutations in Igf-2 and Igf2r, two reciprocally imprinted genes

1 reference

12 December 2020

The ontogeny of allele-specific methylation associated with imprinted genes in the mouse.

1 reference

12 December 2020

Developmental regulation of insulin-like growth factor II mRNA in different rat tissues.

1 reference

12 December 2020

Purification and characterization of a unique high molecular weight form of insulin-like growth factor II.

1 reference

12 December 2020

Loss of imprinting of the IGF2 gene in a Wilms' tumor in an adult

1 reference

12 December 2020

Regulation of human IGF-II transcription in fetal and adult tissues

1 reference

12 December 2020

Expression of the insulin-like growth factor II gene in polychlorinated biphenyl exposed female mink (Mustela vison) and their fetuses

1 reference

12 December 2020

Altered imprinting of the H19 and insulin-like growth factor II genes in testicular tumors

1 reference

12 December 2020

Loss of imprinting of IGF2 in Ewing's sarcoma

1 reference

12 December 2020

p53 Regulates Human Insulin-Like Growth Factor II Gene Expression through Active P4 Promoter in Rhabdomyosarcoma Cells

1 reference

12 December 2020

The conformation of insulin-like growth factors: relationships with insulins

1 reference

12 December 2020

The biological effects of a high molecular weight form of IGF II in a pluripotential human teratocarcinoma cell line.

1 reference

12 December 2020

Hepatic overexpression of insulin-like growth factor-II in adulthood increases basal and insulin-stimulated glucose disposal in conscious mice

1 reference

12 December 2020

Molecular analysis of patients with Wiedemann-Beckwith syndrome. II. Paternally derived disomies of chromosome 11

1 reference

12 December 2020

Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry

1 reference

12 December 2020

Differential imprinting and expression of maternal and paternal genomes

1 reference

12 December 2020

Characterization of rat serum insulin-like growth factor-binding proteins by two-dimensional gel electrophoresis: identification of a potentially novel form

1 reference

12 December 2020

Control of cell proliferation in the human embryonic cornea: an autoradiographic analysis of the effect of growth factors on DNA synthesis in endothelial and stromal cells in organ culture and after explantation in vitro

1 reference

12 December 2020

Report of the Second Chromosome 11 Workshop

1 reference

12 December 2020

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene

1 reference

12 December 2020

Evolution of Insulin-Like Growth Factor II: Characterization of the Mouse IGF-II Gene and Identification of Two Pseudo-Exons

1 reference

12 December 2020

Tissue-specific and developmentally regulated transcription of the insulin-like growth factor 2 gene

1 reference

12 December 2020

10.1111/J.1365-2184.1998.TB01196.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6647699&resulttype=core&format=json

15 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6647699&resulttype=core&format=json

15 May 2020

1 reference