An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development. (Q52125462)

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5 December 2019

title

An allelic series at the PDGFalphaR locus indicates unequal contributions of distinct signaling pathways during development (English)

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5 December 2019

3

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5 December 2019

Philippe Soriano

series ordinal

4

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5 December 2019

author name string

Richard A Klinghoffer

series ordinal

1

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5 December 2019

T Guy Hamilton

series ordinal

2

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5 December 2019

language of work or name

English

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publication date

1 January 2002

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5 December 2019

number of pages

11

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inferred from page(s)

published in

Developmental Cell

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5 December 2019

volume

2

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5 December 2019

page(s)

103-113

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5 December 2019

issue

1

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Type 1 astrocytes and oligodendrocyte-type 2 astrocyte glial progenitors migrate toward distinct molecules

5 December 2019

cites work

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Cell death and control of cell survival in the oligodendrocyte lineage

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Developmental roles of platelet-derived growth factors

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Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3'-kinase is essential for male fertility

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PDGF-A Signaling Is a Critical Event in Lung Alveolar Myofibroblast Development and Alveogenesis

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Oligodendrocyte population dynamics and the role of PDGF in vivo.

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Oncogenes and signal transduction

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Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src

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Platelet-derived growth factor receptor is expressed by cells in the early oligodendrocyte lineage.

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Diverse signaling pathways activated by growth factor receptors induce broadly overlapping, rather than independent, sets of genes

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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A role for Src in signal relay by the platelet-derived growth factor alpha receptor

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Platelet-derived growth factor beta receptor regulates interstitial fluid homeostasis through phosphatidylinositol-3' kinase signaling

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7 January 2021

Signaling--2000 and beyond

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7 January 2021

Functions of the major tyrosine phosphorylation site of the PDGF receptor beta subunit

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7 January 2021

GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit

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7 January 2021

Point mutation in kit receptor tyrosine kinase reveals essential roles for kit signaling in spermatogenesis and oogenesis without affecting other kit responses

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7 January 2021

Src family kinases are required for integrin but not PDGFR signal transduction.

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7 January 2021

The two PDGF receptors maintain conserved signaling in vivo despite divergent embryological functions

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7 January 2021

Reduction of caveolin and caveolae in oncogenically transformed cells

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7 January 2021

Regulation of chemotaxis by the platelet-derived growth factor receptor-beta

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7 January 2021

Mice deficient for PDGF B show renal, cardiovascular, and hematological abnormalities

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7 January 2021

Pericyte loss and microaneurysm formation in PDGF-B-deficient mice

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7 January 2021

Localization of platelet-derived growth factor-stimulated phosphorylation cascade to caveolae

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7 January 2021

Uncoupling of Grb2 from the Met receptor in vivo reveals complex roles in muscle development

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7 January 2021

Coupling Met to specific pathways results in distinct developmental outcomes

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7 January 2021

Oligodendrocyte origins

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7 January 2021

Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses.

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7 January 2021

Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain

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7 January 2021

Platelet-derived growth factor promotes division and motility and inhibits premature differentiation of the oligodendrocyte/type-2 astrocyte progenitor ceil

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7 January 2021

Opposite phenotypes of hypomorphic and Y766 phosphorylation site mutations reveal a function for Fgfr1 in anteroposterior patterning of mouse embryos

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7 January 2021

Protein modules and signalling networks

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7 January 2021

Signaling through scaffold, anchoring, and adaptor proteins

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7 January 2021

Platelet-derived growth factor from astrocytes drives the clock that times oligodendrocyte development in culture.

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7 January 2021

A role for platelet-derived growth factor in normal gliogenesis in the central nervous system.

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Origins of spinal cord oligodendrocytes: possible developmental and evolutionary relationships with motor neurons.

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Identification of the receptor-associated signaling enzymes that are required for platelet-derived growth factor-AA-dependent chemotaxis and DNA synthesis

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7 January 2021

Evidence for distinct signaling properties and biological responses induced by the PDGF receptor alpha and beta subtypes

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7 January 2021

Caveolins in cholesterol trafficking and signal transduction: implications for human disease.

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Cell signaling by receptor tyrosine kinases

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SH2 domains recognize specific phosphopeptide sequences

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Abnormal kidney development and hematological disorders in PDGF beta-receptor mutant mice.

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

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7 January 2021

Epiblast-restricted Cre expression in MORE mice: a tool to distinguish embryonic vs. extra-embryonic gene function.

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7 January 2021

Retention of PDGFR-beta function in mice in the absence of phosphatidylinositol 3'-kinase and phospholipase Cgamma signaling pathways

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7 January 2021

Initial events of myelination involve Fyn tyrosine kinase signalling

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7 January 2021

Phospholipase C-gamma 1 and phosphatidylinositol 3 kinase are the downstream mediators of the PDGF receptor's mitogenic signal

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7 January 2021

PDGF A-chain gene is expressed by mammalian neurons during development and in maturity

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7 January 2021

Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins

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7 January 2021

Tyrosine mutations within the alpha platelet-derived growth factor receptor kinase insert domain abrogate receptor-associated phosphatidylinositol-3 kinase activity without affecting mitogenic or chemotactic signal transduction

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7 January 2021

Biological function of PDGF-induced PI-3 kinase activity: its role in alpha PDGF receptor-mediated mitogenic signaling.

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7 January 2021

Embryonic expression of myelin genes: evidence for a focal source of oligodendrocyte precursors in the ventricular zone of the neural tube

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7 January 2021

10.1016/S1534-5807(01)00103-4

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11782318%20AND%20SRC:MED&resulttype=core&format=json

5 December 2019

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