Points of convergence between Ca2+ and Ras signalling pathways. (Q52035629)

20 April 2018

review article

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title

Points of convergence between Ca2+ and Ras signalling pathways. (English)

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20 April 2018

author name string

D J Gawler

series ordinal

1

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20 April 2018

publication date

1 December 1998

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20 April 2018

Biochimica et Biophysica Acta

published in

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20 April 2018

volume

1448

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20 April 2018

issue

2

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20 April 2018

page(s)

171-182

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20 April 2018

https://api.crossref.org/works/10.1016%2FS0167-4889%2898%2900141-4

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7 January 2021

The p21 ras C-terminus is required for transformation and membrane association

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Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein

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Function and regulation of ras.

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

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Identification of small clusters of divergent amino acids that mediate the opposing effects of ras and Krev-1.

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Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells

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Proteins regulating Ras and its relatives

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Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2

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Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras

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Molecular cloning of cDNAs encoding a guanine-nucleotide-releasing factor for Ras p21

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Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

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Ras1 and a putative guanine nucleotide exchange factor perform crucial steps in signaling by the sevenless protein tyrosine kinase.

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Interactions between Src homology (SH) 2/SH3 adapter proteins and the guanylnucleotide exchange factor SOS are differentially regulated by insulin and epidermal growth factor

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Epidermal growth factor regulates p21ras through the formation of a complex of receptor, Grb2 adapter protein, and Sos nucleotide exchange factor

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In vivo functional analysis of the Ras exchange factor son of sevenless

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Functional roles for the pleckstrin and Dbl homology regions in the Ras exchange factor Son-of-sevenless

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Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1.

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The Ras Guanine nucleotide Exchange Factor CDC25Mm is present at the synaptic junction.

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Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

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The N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calcium

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Heterotrimeric G proteins: organizers of transmembrane signals

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7 January 2021

Activation of the exchange factor Ras-GRF by calcium requires an intact Dbl homology domain

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7 January 2021

Activation of R-Ras by Ras-guanine nucleotide-releasing factor

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7 January 2021

A role for the Ras signalling pathway in synaptic transmission and long-term memory

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Cloning of bovine GAP and its interaction with oncogenic ras p21.

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A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions

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Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

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GapIII, a new brain-enriched member of the GTPase-activating protein family

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A novel GTPase-activating protein for R-Ras

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cDNA cloning of the type 1 neurofibromatosis gene: complete sequence of the NF1 gene product

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A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II

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The catalytic domain of the neurofibromatosis type 1 gene product stimulates ras GTPase and complements ira mutants of S. cerevisiae

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Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

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Identification of the SH3 domain of GAP as an essential sequence for Ras-GAP-mediated signaling

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A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP

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Mutation-deletion analysis of a Ca(2+)-dependent phospholipid binding (CaLB) domain within p120 GAP, a GTPase-activating protein for p21 ras.

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The Ca2+-dependent lipid binding domain of P120GAP mediates protein-protein interactions with Ca2+-dependent membrane-binding proteins. Evidence for a direct interaction between annexin VI and P120GAP

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Inositol 1,3,4,5-tetrakisphosphate binding activities of neuronal and non-neuronal synaptotagmins. Identification of conserved amino acid substitutions that abolish inositol 1,3,4,5-tetrakisphosphate binding to synaptotagmins III, V, and X.

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Purification and characterization of an Ins(1,3,4,5)P4 binding protein from pig platelets: possible identification of a novel non-neuronal Ins(1,3,4,5)P4 receptor

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Structure-function relationships of the mouse Gap1m. Determination of the inositol 1,3,4,5-tetrakisphosphate-binding domain.

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Inositol 1,3,4,5-tetrakisphosphate and inositol 1,4,5-trisphosphate act by different mechanisms when controlling Ca2+ in mouse lacrimal acinar cells

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Regulation of rat neuronal voltage-dependent calcium channels by endogenous p21-ras

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Dimerization of cell surface receptors in signal transduction

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SH2 domains recognize specific phosphopeptide sequences

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PDGF stimulation of inositol phospholipid hydrolysis requires PLC-gamma 1 phosphorylation on tyrosine residues 783 and 1254.

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Pertussis toxin-sensitive activation of p21ras by G protein-coupled receptor agonists in fibroblasts

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RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts

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A role for Pyk2 and Src in linking G-protein-coupled receptors with MAP kinase activation

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SH2/SH3 signaling proteins

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Protein tyrosine kinase PYK2 involved in Ca(2+)-induced regulation of ion channel and MAP kinase functions

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Differential regulation of proline-rich tyrosine kinase 2/cell adhesion kinase beta (PYK2/CAKbeta) and pp125(FAK) by glutamate and depolarization in rat hippocampus.

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Activation of protein tyrosine kinase PYK2 by the m1 muscarinic acetylcholine receptor

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Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling

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Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase

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Role of transactivation of the EGF receptor in signalling by G-protein-coupled receptors

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Gi-mediated activation of the Ras/MAP kinase pathway involves a 100 kDa tyrosine-phosphorylated Grb2 SH3 binding protein, but not Src nor Shc

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Inhibition of tyrosine phosphorylation prevents T-cell receptor-mediated signal transduction

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Rapid activation of the T-cell tyrosine protein kinase pp56lck by the CD45 phosphotyrosine phosphatase

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T cell antigen receptor-mediated activation of phospholipase C requires tyrosine phosphorylation

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Ca2+ channel activation by platelet-derived growth factor-induced tyrosine phosphorylation and Ras guanine triphosphate-binding proteins in rat glomerular mesangial cells

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Modulation of voltage-dependent Ca2+ channels in rabbit colonic smooth muscle cells by c-Src and focal adhesion kinase.

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Identifiers

DOI

1 reference

20 April 2018

PubMed ID

9920408

1 reference

20 April 2018