Emerging high-throughput drug target validation technologies. (Q52023842)

20 April 2018

title

Emerging high-throughput drug target validation technologies. (English)

1 reference

20 April 2018

author name string

Leodevico L Ilag

1

1 reference

20 April 2018

Jocelyn H Ng

2

1 reference

20 April 2018

Gerald Beste

3

1 reference

20 April 2018

Stefan W Henning

4

1 reference

20 April 2018

publication date

1 September 2002

1 reference

20 April 2018

published in

Drug Discovery Today

1 reference

20 April 2018

volume

7

1 reference

20 April 2018

issue

18 Suppl

1 reference

20 April 2018

page(s)

S136-42

1 reference

20 April 2018

cites work

Moonlighting proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Genetic approaches to the analysis of microbial development

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Identification of Id4 as a regulator of BRCA1 expression by using a ribozyme-library-based inverse genomics approach

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

The use of retroviruses as pharmaceutical tools for target discovery and validation in the field of functional genomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Functional cloning of Src-like adapter protein-2 (SLAP-2), a novel inhibitor of antigen receptor signaling

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

A high-throughput alphavirus-based expression cloning system for mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Multiple immediate-early gene-deficient herpes simplex virus vectors allowing efficient gene delivery to neurons in culture and widespread gene delivery to the central nervous system in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Robotic high-throughput assay for isolating apoptosis-inducing genes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Identification and validation of a gene involved in anchorage-independent cell growth control using a library of randomized hairpin ribozymes

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

A novel functional genomics approach identifies mTERT as a suppressor of fibroblast transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Functional genomics and target validation approaches using antisense oligonucleotide technology

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Morpholino oligos: making sense of antisense?

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Photo-mediated gene activation using caged RNA/DNA in zebrafish embryos

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

RNA interference: mechanisms and applications

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Double-stranded RNA injection produces nonspecific defects in zebrafish.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

A system for stable expression of short interfering RNAs in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Effective expression of small interfering RNA in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Antisense and sensibility

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

A peptide carrier for the delivery of biologically active proteins into mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Antigen-independent selection of stable intracellular single-chain antibodies

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Molecular inactivation. Spatially and temporally defined molecular knockouts

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Automated RNA selection.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

RNA aptamers as effective protein antagonists in a multicellular organism

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Intramers as promising new tools in functional proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Transdominant genetic analysis of a growth control pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Dominant effector genetics in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Target-oriented and diversity-oriented organic synthesis in drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Chemical ligands, genomics and drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

FLEXGene repository: from sequenced genomes to gene repositories for high-throughput functional biology and proteomics

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Proteome-scale purification of human proteins from bacteria

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

A biochemical genomics approach for identifying genes by the activity of their products.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Global analysis of protein activities using proteome chips

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Membrane protein microarrays.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Fluorophore-assisted light inactivation: a high-throughput tool for direct target validation of proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

Functional proteomics using chromophore-assisted laser inactivation

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2802%2902429-7

7 January 2021

10.1016/S1359-6446(02)02429-7

Identifiers

DOI

1 reference

20 April 2018

1 reference

20 April 2018