Metabolism of [14C]trichloroethylene to 14CO2 and interaction of a metabolite with liver DNA in rats and mice. (Q51861574)

14 April 2018

title

Metabolism of [14C]trichloroethylene to 14CO2 and interaction of a metabolite with liver DNA in rats and mice. (English)

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author name string

Parchman LG

series ordinal

1

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Magee PN

series ordinal

2

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publication date

1 May 1982

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Journal of Toxicology and Environmental Health

published in

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volume

9

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page(s)

797-813

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issue

5-6

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Incubation of 14C-trichloroethylene vapor with rat liver microsomes: uptake of radioactivity and covalent protein binding of metabolites

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1 reference

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Mutagenicity in vitro and potential carcinogenicity of chlorinated ethylenes as a function of metabolic oxirane formation

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Consideration of the evidence for mechanisms of 1,1,2-trichloroethylene metabolism, including new identification of its dichloroacetic acid and trichloroacetic acid metabolites in mice

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Reaction of DNA with alkylating agents. Quantitation of alkylation by ethylnitrosourea of oxygen and nitrogen sites on poly[dA-dT] including phosphotriester formation

21 January 2018

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The in vitro methylation of DNA by microsomally-activated dimethylnitrosamine and its correlation with formaldehyde production.

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In vivo covalent binding of organic chemicals to DNA as a quantitative indicator in the process of chemical carcinogenesis

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Range-Finding Toxicity Data: List VII

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Irreversible binding of 14C-labelled trichloroethylene to mice liver constituents in vivo and in vitro

21 January 2018

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Spectral evidence for 2,2,3-trichloro-oxirane formation during microsomal trichloroethylene oxidation

21 January 2018

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On the possible mechanism of carcinogenic action of vinyl chloride

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Identifiers

DOI

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14 April 2018

PubMed ID

6811765

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14 April 2018