Ganglioside GD1a is an essential coreceptor for Toll-like receptor 2 signaling in response to the B subunit of type IIb enterotoxin. (Q51800575)

12 April 2018

title

Ganglioside GD1a is an essential coreceptor for Toll-like receptor 2 signaling in response to the B subunit of type IIb enterotoxin. (English)

1 reference

12 April 2018

main subject

toll-like receptor

0 references

author

George Hajishengallis

9

1 reference

12 April 2018

author name string

Shuang Liang

1

1 reference

12 April 2018

Min Wang

2

1 reference

12 April 2018

Richard I Tapping

3

1 reference

12 April 2018

Vitaly Stepensky

4

1 reference

12 April 2018

Hesham F Nawar

5

1 reference

12 April 2018

Martha Triantafilou

6

1 reference

12 April 2018

Kathy Triantafilou

7

1 reference

12 April 2018

Terry D Connell

8

1 reference

12 April 2018

language of work or name

English

0 references

publication date

16 January 2007

1 reference

12 April 2018

Journal of Biological Chemistry

published in

1 reference

12 April 2018

volume

282

1 reference

12 April 2018

page(s)

7532-7542

1 reference

12 April 2018

issue

10

1 reference

12 April 2018

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Lipopolysaccharide recognition: CD14, TLRs and the LPS-activation cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Differential interactions of fimbriae and lipopolysaccharide from Porphyromonas gingivalis with the Toll-like receptor 2-centred pattern recognition apparatus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

A CD14-independent LPS receptor cluster

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Lipopolysaccharide rapidly traffics to and from the Golgi apparatus with the toll-like receptor 4-MD-2-CD14 complex in a process that is distinct from the initiation of signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Toll-like receptor 2 mediates cellular activation by the B subunits of type II heat-labile enterotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

The Type II heat-labile enterotoxins LT-IIa and LT-IIb and their respective B pentamers differentially induce and regulate cytokine production in human monocytic cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

TLR2 transmodulates monocyte adhesion and transmigration via Rac1- and PI3K-mediated inside-out signaling in response to Porphyromonas gingivalis fimbriae

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Peptide mapping of bacterial fimbrial epitopes interacting with pattern recognition receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Chinese hamster ovary cells lacking GM1 and GD1a synthesize gangliosides upon transfection with human GM2 synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Toll-like receptor 4 and Toll-IL-1 receptor domain-containing adapter protein (TIRAP)/myeloid differentiation protein 88 adapter-like (Mal) contribute to maximal IL-6 expression in macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

TLR4, but not TLR2, mediates IFN-beta-induced STAT1alpha/beta-dependent gene expression in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

TIRAP: an adapter molecule in the Toll signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Ability of blood group A-active glycosphingolipids to act as Escherichia coli heat-labile enterotoxin receptors in HT-29 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Integrin activation by bacterial fimbriae through a pathway involving CD14, Toll-like receptor 2, and phosphatidylinositol-3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Meningococcal porin PorB binds to TLR2 and requires TLR1 for signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Real-time analysis of the effects of cholesterol on lipid raft behavior using atomic force microscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Combinational clustering of receptors following stimulation by bacterial products determines lipopolysaccharide responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Novel engagement of CD14 and multiple toll-like receptors by group B streptococci.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

TLR2 is mobilized into an apical lipid raft receptor complex to signal infection in airway epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

The adaptor molecule TIRAP provides signalling specificity for Toll-like receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Phosphoinositide-mediated adaptor recruitment controls Toll-like receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

CD36 is a sensor of diacylglycerides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Pneumocystis-mediated IL-8 release by macrophages requires coexpression of mannose receptors and TLR2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Domain exchange between human toll-like receptors 1 and 6 reveals a region required for lipopeptide discrimination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Toll-like receptor-2 mediates Treponema glycolipid and lipoteichoic acid-induced NF-kappaB translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Sigma-1 receptors potentiate epidermal growth factor signaling towards neuritogenesis in PC12 cells: potential relation to lipid raft reconstitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Cholera holotoxin assembly requires a hydrophobic domain at the A-B5 interface: mutational analysis and development of an in vitro assembly system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Crystal structure of a new heat-labile enterotoxin, LT-IIb

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Relationship between structures and biological activities of mycoplasmal diacylated lipopeptides and their recognition by toll-like receptors 2 and 6

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Mycoplasma fermentans lipoprotein M161Ag-induced cell activation is mediated by Toll-like receptor 2: role of N-terminal hydrophobic portion in its multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Hydrophobicity: an ancient damage-associated molecular pattern that initiates innate immune responses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

AsialoGM1-mediated IL-8 release by human corneal epithelial cells requires coexpression of TLR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Gangliosides are receptors for murine polyoma virus and SV40

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Pseudomonas aeruginosa Flagella Activate Airway Epithelial Cells through asialoGM1 and Toll-Like Receptor 2 as well as Toll-Like Receptor 5

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Gangliosides act as co-receptors for Salmonella enteritidis FliC and promote FliC induction of human beta-defensin-2 expression in Caco-2 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Polyoma virus-like particles elicit polarized cytokine responses in APCs from tumor-susceptible and -resistant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Cell membrane GM1 ganglioside is a functional coreceptor for fibroblast growth factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Immunomodulation with enterotoxins for the generation of secretory immunity or tolerance: applications for oral infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Mutant Escherichia coli heat-labile toxin B subunit that separates toxoid-mediated signaling and immunomodulatory action from trafficking and delivery functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

Toll-like receptor control of the adaptive immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M611722200

21 January 2018

Identifiers

DOI

10.1074/JBC.M611722200

1 reference

12 April 2018

PubMed ID

17227759

1 reference

12 April 2018