Involvement of multidrug resistance-associated protein 1 in intestinal toxicity of methotrexate. (Q51767832)

11 April 2018

title

Involvement of multidrug resistance-associated protein 1 in intestinal toxicity of methotrexate. (English)

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11 April 2018

main subject

multiple drug resistance

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5

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11 April 2018

author name string

Sayaka Kato

1

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11 April 2018

Katsuaki Ito

2

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11 April 2018

Yukio Kato

3

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11 April 2018

Tomohiko Wakayama

4

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11 April 2018

Shoichi Iseki

6

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11 April 2018

Akira Tsuji

7

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11 April 2018

publication date

14 March 2009

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11 April 2018

published in

Pharmaceutical Research

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11 April 2018

volume

26

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11 April 2018

issue

6

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page(s)

1467-1476

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11 April 2018

Sequence, tissue distribution and developmental changes in rat intestinal oligopeptide transporter

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The predominant contribution of oligopeptide transporter PepT1 to intestinal absorption of beta-lactam antibiotics in the rat small intestine.

21 January 2018

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Polarized trafficking of E-cadherin is regulated by Rac1 and Cdc42 in Madin-Darby canine kidney cells.

21 January 2018

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Active secretion of drugs from the small intestinal epithelium in rats by P-glycoprotein functioning as an absorption barrier

21 January 2018

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https://api.crossref.org/works/10.1007%2FS11095-009-9858-6

Tissue and cell distribution of the multidrug resistance-associated protein (MRP) in mouse intestine and kidney

21 January 2018

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Contributions of mucosal immune cells to methotrexate-induced mucositis.

21 January 2018

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12 December 2020

Protection of the Peyer's patch-associated crypt and villus epithelium against methotrexate-induced damage is based on its distinct regulation of proliferation

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12 December 2020

Oxidative stress contributes to methotrexate-induced small intestinal toxicity in rats

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12 December 2020

Methotrexate-induced mucositis in mucin 2-deficient mice.

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12 December 2020

Cell turnover in the rat small intestinal mucosa: an appraisal of cell loss

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12 December 2020

Involvement of multidrug resistance-associated protein 2 in intestinal secretion of grepafloxacin in rats

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12 December 2020

Expression and localization of the multidrug resistance-associated protein 3 in rat small and large intestine.

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12 December 2020

Identification of an intestinal heme transporter

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12 December 2020

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12 December 2020

Altered expression of sulfotransferases, glucuronosyltransferases and mrp transporters in FVB/mrp1-/- mice

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12 December 2020

Characterization of methotrexate transport and its drug interactions with human organic anion transporters

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12 December 2020

CPT-11 in gastrointestinal cancer

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12 December 2020

Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption

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12 December 2020

Inhibition of biliary excretion of methotrexate by probenecid in rats: quantitative prediction of interaction from in vitro data

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12 December 2020

Modified irinotecan hydrochloride (CPT-11) administration schedule improves induction of delayed-onset diarrhea in rats

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12 December 2020

Preservation of folate transport activity with a low-pH optimum in rat IEC-6 intestinal epithelial cell lines that lack reduced folate carrier function

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12 December 2020

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. V. Unitarian Theory of the origin of the four epithelial cell types

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12 December 2020

Transport of methotrexate (MTX) and folates by multidrug resistance protein (MRP) 3 and MRP1: effect of polyglutamylation on MTX transport.

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12 December 2020

Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione.

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12 December 2020

ATP-Dependent efflux of CPT-11 and SN-38 by the multidrug resistance protein (MRP) and its inhibition by PAK-104P

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12 December 2020

Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein

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12 December 2020

Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage.

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12 December 2020

The enterohepatic circulation of methotrexate in vivo: inhibition by bile salt

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12 December 2020

Camptothecin and podophyllotoxin derivatives: inhibitors of topoisomerase I and II - mechanisms of action, pharmacokinetics and toxicity profile

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12 December 2020

Enterohepatic circulation of methotrexate in rats in vivo

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12 December 2020

Recombinant human granulocyte colony-stimulating factor. Effects on hematopoiesis in normal and cyclophosphamide-treated primates

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12 December 2020

Intestinal epithelial cell surface membrane glycoprotein synthesis. I. An indicator of cellular differentiation.

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12 December 2020

Methotrexate is excreted into the bile by canalicular multispecific organic anion transporter in rats

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12 December 2020

Mechanism of the pharmacokinetic interaction between methotrexate and benzimidazoles: potential role for breast cancer resistance protein in clinical drug-drug interactions

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12 December 2020

The metabolic fate of tritiated methotrexate. I. Absorption, excretion, and distribution in mice, rats, dogs and monkeys

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12 December 2020

Multidrug resistance protein 1 protects the oropharyngeal mucosal layer and the testicular tubules against drug-induced damage

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12 December 2020

The role of P-glycoprotein in intestinal tumorigenesis: disruption of mdr1a suppresses polyp formation in Apc(Min/+) mice

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12 December 2020

Expression of the breast cancer resistance protein (Bcrp1/Abcg2) in tissues from pregnant mice: effects of pregnancy and correlations with nuclear receptors

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12 December 2020

Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11.

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12 December 2020

Localization of the murine reduced folate carrier as assessed by immunohistochemical analysis

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12 December 2020

10.1007/S11095-009-9858-6

Identifiers

DOI

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11 April 2018

PubMed ID

19288182

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11 April 2018